Burden of primary influenza and respiratory syncytial virus pneumonia in hospitalized adults: insights from a two-year multi-centre cohort study (2017-2018)

This two-year (2017-2018) multi-centre study on 356 adults hospitalized for influenza A/B and RSV pneumonia analysed factors associated with non-invasive ventilation (NIV) failure and in-hospital death (IHD.) Patients with both obstructive sleep apnoea or obesity hypoventilation syndrome and influenza-A virus pneumonia showed a higher risk for NIV failure (OR 4.66; 95% CI 1.42-15.30). Patients submitted to NIV showed a higher risk for IHD, regardless of comorbidities (influenza-A OR 3.00; 95% CI 1.35-6.65, influenza-B OR 4.52; 95% CI 1.13-18.01, RSV OR 5.61; 95% CI 1.26-24.93). The increased knowledge of influenza-A/B and RSV pneumonia burden may contribute to a better management of patients with viral pneumonia. This article is protected by copyright. All rights reserved.