The Transplant Centers belonging to Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO) conducted a survey with the aim of evaluating the effect of SARS-CoV2 pandemic on the allogeneic transplant activity in Italy. The pandemic period from 1/3/2020 to 31/7/2020 was compared with the same period in 2019. Overall, in 2020 there was a 2.4% reduction in the number of allo-HCT cases compared to 2019. Interestingly, this deflection did not affect the acute leukemia cases (+5.7% in 2020). The use of peripheral blood-derived stem cells (+10.7%) and cryopreservation (97.4% of the centers) was highly adopted in 2020. Despite the sanitary emergency, almost all of the surveyed centers declared no impact of SARS-CoV2 pandemic on the transplant timing and outcomes, and the sanitary policy was positively evaluated by the majority of centers. The emergency measures ensured that only a minority of the allo-HCT patients had been infected by SARS-CoV2; however, a mortality of 42.1% among the allo-HCT patients hospitalized for COVID-19 was recorded. This survey gives us the information that the GITMO Group reacted positively to the pandemic. Thanks to the emergency strategies, the Italian allo-HCT activity continued safely, showing only a minor deflection and offering the same probability of cure to the transplanted patients.

Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)

Federico V.
Membro del Collaboration Group
;
Piemontese S.
Membro del Collaboration Group
;
Picardi A.
Membro del Collaboration Group
;
De Gobbi M.
Membro del Collaboration Group
;
Fagioli F.
Membro del Collaboration Group
;
2021-01-01

Abstract

The Transplant Centers belonging to Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO) conducted a survey with the aim of evaluating the effect of SARS-CoV2 pandemic on the allogeneic transplant activity in Italy. The pandemic period from 1/3/2020 to 31/7/2020 was compared with the same period in 2019. Overall, in 2020 there was a 2.4% reduction in the number of allo-HCT cases compared to 2019. Interestingly, this deflection did not affect the acute leukemia cases (+5.7% in 2020). The use of peripheral blood-derived stem cells (+10.7%) and cryopreservation (97.4% of the centers) was highly adopted in 2020. Despite the sanitary emergency, almost all of the surveyed centers declared no impact of SARS-CoV2 pandemic on the transplant timing and outcomes, and the sanitary policy was positively evaluated by the majority of centers. The emergency measures ensured that only a minority of the allo-HCT patients had been infected by SARS-CoV2; however, a mortality of 42.1% among the allo-HCT patients hospitalized for COVID-19 was recorded. This survey gives us the information that the GITMO Group reacted positively to the pandemic. Thanks to the emergency strategies, the Italian allo-HCT activity continued safely, showing only a minor deflection and offering the same probability of cure to the transplanted patients.
2021
56
9
2272
2275
Humans; Italy; Pandemics; RNA, Viral; SARS-CoV-2; Stem Cell Transplantation; Transplantation, Homologous; COVID-19; Hematopoietic Stem Cell Transplantation; Leukemia, Myeloid, Acute
Russo D.; Polverelli N.; Malagola M.; Farina M.; Leoni A.; Bernardi S.; Mammoliti S.; Sacchi N.; Martino M.; Ciceri F.; Zallio F.; Olivieri A.; Falcioni S.; Storti G.; Michieli M.; Carluccio P.; Grassi A.; Oldani E.; Bonifazi F.; Prete A.; Cavattoni I.M.; Maffeis M.; Pastore D.; Vacca A.; Caravelli D.; Mirabile M.; Mordini N.; Nozzoli C.; Faraci M.; Federico V.; Ronconi S.; Skert C.; Onida F.; Marcatti M.; Piemontese S.; Narni F.; Balduzzi A.; De Simone G.; Picardi A.; De Gobbi M.; Calore E.; Tringali S.; Zecca M.; Secondino S.; Guiducci B.; Pelosini M.; Zuffa E.; Facchini L.; Imola M.; Iori A.P.; Proia A.; Sica S.; Armiento D.; Carella A.M.; Dellacasa C.M.; Fagioli F.; Rabusin M.; Ferrario A.; Elice F.
File in questo prodotto:
File Dimensione Formato  
41409_2021_Article_1287.pdf

Accesso aperto

Tipo di file: PDF EDITORIALE
Dimensione 414.1 kB
Formato Adobe PDF
414.1 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1822994
Citazioni
  • ???jsp.display-item.citation.pmc??? 8
  • Scopus 13
  • ???jsp.display-item.citation.isi??? 12
social impact