The Transplant Centers belonging to Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO) conducted a survey with the aim of evaluating the effect of SARS-CoV2 pandemic on the allogeneic transplant activity in Italy. The pandemic period from 1/3/2020 to 31/7/2020 was compared with the same period in 2019. Overall, in 2020 there was a 2.4% reduction in the number of allo-HCT cases compared to 2019. Interestingly, this deflection did not affect the acute leukemia cases (+5.7% in 2020). The use of peripheral blood-derived stem cells (+10.7%) and cryopreservation (97.4% of the centers) was highly adopted in 2020. Despite the sanitary emergency, almost all of the surveyed centers declared no impact of SARS-CoV2 pandemic on the transplant timing and outcomes, and the sanitary policy was positively evaluated by the majority of centers. The emergency measures ensured that only a minority of the allo-HCT patients had been infected by SARS-CoV2; however, a mortality of 42.1% among the allo-HCT patients hospitalized for COVID-19 was recorded. This survey gives us the information that the GITMO Group reacted positively to the pandemic. Thanks to the emergency strategies, the Italian allo-HCT activity continued safely, showing only a minor deflection and offering the same probability of cure to the transplanted patients.

Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)

Maffeis M.;Caravelli D.;Faraci M.;Federico V.;Piemontese S.;Picardi A.;De Gobbi M.;Tringali S.;Sica S.;Dellacasa C. M.;Fagioli F.;
2021

Abstract

The Transplant Centers belonging to Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO) conducted a survey with the aim of evaluating the effect of SARS-CoV2 pandemic on the allogeneic transplant activity in Italy. The pandemic period from 1/3/2020 to 31/7/2020 was compared with the same period in 2019. Overall, in 2020 there was a 2.4% reduction in the number of allo-HCT cases compared to 2019. Interestingly, this deflection did not affect the acute leukemia cases (+5.7% in 2020). The use of peripheral blood-derived stem cells (+10.7%) and cryopreservation (97.4% of the centers) was highly adopted in 2020. Despite the sanitary emergency, almost all of the surveyed centers declared no impact of SARS-CoV2 pandemic on the transplant timing and outcomes, and the sanitary policy was positively evaluated by the majority of centers. The emergency measures ensured that only a minority of the allo-HCT patients had been infected by SARS-CoV2; however, a mortality of 42.1% among the allo-HCT patients hospitalized for COVID-19 was recorded. This survey gives us the information that the GITMO Group reacted positively to the pandemic. Thanks to the emergency strategies, the Italian allo-HCT activity continued safely, showing only a minor deflection and offering the same probability of cure to the transplanted patients.
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Humans; Italy; Pandemics; RNA, Viral; SARS-CoV-2; Stem Cell Transplantation; Transplantation, Homologous; COVID-19; Hematopoietic Stem Cell Transplantation; Leukemia, Myeloid, Acute
Russo D.; Polverelli N.; Malagola M.; Farina M.; Leoni A.; Bernardi S.; Mammoliti S.; Sacchi N.; Martino M.; Ciceri F.; Zallio F.; Olivieri A.; Falcioni S.; Storti G.; Michieli M.; Carluccio P.; Grassi A.; Oldani E.; Bonifazi F.; Prete A.; Cavattoni I.M.; Maffeis M.; Pastore D.; Vacca A.; Caravelli D.; Mirabile M.; Mordini N.; Nozzoli C.; Faraci M.; Federico V.; Ronconi S.; Skert C.; Onida F.; Marcatti M.; Piemontese S.; Narni F.; Balduzzi A.; De Simone G.; Picardi A.; De Gobbi M.; Calore E.; Tringali S.; Zecca M.; Secondino S.; Guiducci B.; Pelosini M.; Zuffa E.; Facchini L.; Imola M.; Iori A.P.; Proia A.; Sica S.; Armiento D.; Carella A.M.; Dellacasa C.M.; Fagioli F.; Rabusin M.; Ferrario A.; Elice F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1822994
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