A new study in zebrafish shows that Birc2, a member of the inhibitor of apoptosis (IAP) family, is required for endothelial cell survival. This discovery highlights an important in vivo function of this molecule and suggests potential avenues for the development of new antiangiogenic therapies. © 2007 Nature Publishing Group.

Building in resistance to endothelial cell death

Mazzone M.;
2007-01-01

Abstract

A new study in zebrafish shows that Birc2, a member of the inhibitor of apoptosis (IAP) family, is required for endothelial cell survival. This discovery highlights an important in vivo function of this molecule and suggests potential avenues for the development of new antiangiogenic therapies. © 2007 Nature Publishing Group.
2007
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11
1308
1309
Angiogenesis Inhibitors; Animals; Cell Survival; Endothelium, Vascular; Inhibitor of Apoptosis Proteins; NF-kappa B; TNF Receptor-Associated Factor 2; Zebrafish; Zebrafish Proteins
Mazzone M.; De Almodovar C.R.; Carmeliet P.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1841074
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