Hemopexin is the plasma protein with the highest affinity for heme. Seminal studies have highlighted its role in different kinds of heme‐associated disorders, but its implication in cancer has been neglected for a long time. Considering the emerging importance of heme in tumors, the present review proposes an update of the works investigating hemopexin involvement in cancer, with the attempt to stimulate further future studies on this topic.

Hemopexin and Cancer

Fiorito V.
;
Tolosano E.
2022-01-01

Abstract

Hemopexin is the plasma protein with the highest affinity for heme. Seminal studies have highlighted its role in different kinds of heme‐associated disorders, but its implication in cancer has been neglected for a long time. Considering the emerging importance of heme in tumors, the present review proposes an update of the works investigating hemopexin involvement in cancer, with the attempt to stimulate further future studies on this topic.
2022
23
997
1
7
Cancer; Heme; Hemopexin; Disease Progression; Hemopexin; Humans; Membrane Transport Proteins; Neoplasms; Receptors, Virus
Fiorito V.; Tolosano E.
File in questo prodotto:
File Dimensione Formato  
2022_ijms_Fiorito and Tolosano.pdf

Accesso aperto

Tipo di file: PDF EDITORIALE
Dimensione 501.28 kB
Formato Adobe PDF
501.28 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1843121
Citazioni
  • ???jsp.display-item.citation.pmc??? 5
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 7
social impact