Objective: To compare stent-related symptoms (SRS) of loop-tail (LT) and conventional double J (DJ) stents after uncomplicated flexible ureterorenoscopy (fURS), in a prospective randomised controlled single-blind parallel-group study. Patients and Methods: Patients undergoing fURS were randomised into two groups: the LT Group received LT stents (Polaris™ Loop) and the DJ Group received conventional DJ stents (Vortek®). The stent was removed after 4 weeks. The Ureteric Stent Symptom Questionnaire (USSQ) was administered at 2 days, 4 and 8 weeks (baseline evaluation) after stent insertion. The primary endpoint was to compare the Urinary Symptom Index Score of the LT vs DJ groups at 4 weeks after stent insertion. The secondary endpoints were to compare the USSQ domains’ subscores at 2 days and 4 weeks after stent insertion, USSQ single answers at 4 weeks, and the 4-week USSQ domains’ subscores adjusted for baseline. Results: A total of 68 patients were randomised (34 LT and 34 DJ). The answers given at 4 weeks were not significantly different between the two groups for the Urinary Symptom Index Score (P = 0.982), Pain Index Score (P = 0.169), visual analogue scale (P = 0.276), and all the other domains of the USSQ. At 4 weeks, the single-answer analysis did not find any differences between the groups; the urinary symptoms were all comparable, as was the requirement for pain painkillers (P = 0.684) and pain during sex (P = 0.496). There were also no significant differences for every single domain score for the responses given at 2 days. The same applied to USSQ subscores at 4 weeks adjusted for the 8-week baseline results, which were also comparable. Conclusions: The study found no differences in terms of SRS between the LT and DJ groups, either at 2 days or 4 weeks after stent insertion, with or without baseline correction.
Titolo: | Loop-tail stents fail in reducing stent-related symptoms: results of a prospective randomised controlled trial | |
Autori Riconosciuti: | ||
Autori: | Bosio A.; Alessandria E.; Agosti S.C.; Vitiello F.; Vercelli E.; Bisconti A.; Fop F.; Gontero P. | |
Data di pubblicazione: | 2022 | |
Abstract: | Objective: To compare stent-related symptoms (SRS) of loop-tail (LT) and conventional double J (DJ) stents after uncomplicated flexible ureterorenoscopy (fURS), in a prospective randomised controlled single-blind parallel-group study. Patients and Methods: Patients undergoing fURS were randomised into two groups: the LT Group received LT stents (Polaris™ Loop) and the DJ Group received conventional DJ stents (Vortek®). The stent was removed after 4 weeks. The Ureteric Stent Symptom Questionnaire (USSQ) was administered at 2 days, 4 and 8 weeks (baseline evaluation) after stent insertion. The primary endpoint was to compare the Urinary Symptom Index Score of the LT vs DJ groups at 4 weeks after stent insertion. The secondary endpoints were to compare the USSQ domains’ subscores at 2 days and 4 weeks after stent insertion, USSQ single answers at 4 weeks, and the 4-week USSQ domains’ subscores adjusted for baseline. Results: A total of 68 patients were randomised (34 LT and 34 DJ). The answers given at 4 weeks were not significantly different between the two groups for the Urinary Symptom Index Score (P = 0.982), Pain Index Score (P = 0.169), visual analogue scale (P = 0.276), and all the other domains of the USSQ. At 4 weeks, the single-answer analysis did not find any differences between the groups; the urinary symptoms were all comparable, as was the requirement for pain painkillers (P = 0.684) and pain during sex (P = 0.496). There were also no significant differences for every single domain score for the responses given at 2 days. The same applied to USSQ subscores at 4 weeks adjusted for the 8-week baseline results, which were also comparable. Conclusions: The study found no differences in terms of SRS between the LT and DJ groups, either at 2 days or 4 weeks after stent insertion, with or without baseline correction. | |
Volume: | 129 | |
Fascicolo: | 1 | |
Pagina iniziale: | 123 | |
Pagina finale: | 129 | |
Digital Object Identifier (DOI): | 10.1111/bju.15395 | |
Parole Chiave: | #EndoUrology; #Urology; LUTS; RIRS; URS; double J; loop-tail stents; pain; stent-related symptoms; stents; ureteroscopy; urinary calculi; Aged; Analgesics; Dyspareunia; Equipment Design; Female; Humans; Kidney Calculi; Male; Middle Aged; Pain; Prospective Studies; Sexual Behavior; Single-Blind Method; Stents; Surveys and Questionnaires; Symptom Assessment; Time Factors; Ureteroscopy | |
Rivista: | BJU INTERNATIONAL | |
Appare nelle tipologie: | 03A-Articolo su Rivista |
File in questo prodotto:
File | Descrizione | Tipologia | Licenza | |
---|---|---|---|---|
BJU International - 2021 - Bosio - Loop‐tail stents fail in reducing stent‐related symptoms results of a prospective.pdf | PDF EDITORIALE | Utenti riconosciuti Richiedi una copia |