CINECA IRIS Institutional Research Information System

Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance.

Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models

Foglietta, Federica;
2018-01-01

Abstract

Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance.
2018
13
4847
4867
breast cancer; keratin; nanoparticles; paclitaxel; perfused three-dimensional models; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Survival; Drug Liberation; Female; Gene Expression Regulation, Neoplastic; Humans; Keratins; MCF-7 Cells; Nanoparticles; Paclitaxel; Models, Biological
Foglietta, Federica; Spagnoli, Giulio C; Muraro, Manuele Giuseppe; Ballestri, Marco; Guerrini, Andrea; Ferroni, Claudia; Aluigi, Annalisa; Sotgiu, Gio...espandi
03A-Articolo su Rivista
File in questo prodotto:
File Dimensione Formato  
Foglietta F. 2018.pdf

Accesso aperto

Tipo di file: PDF EDITORIALE
Dimensione 8.72 MB
Formato Adobe PDF
Visualizza/Apri
8.72 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1869099
Citazioni
  • ???jsp.display-item.citation.pmc??? 7
  • Scopus 31
  • ???jsp.display-item.citation.isi??? 31
social impact