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Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance.

Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models

Foglietta, Federica;
2018-01-01

Abstract

Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance.
2018
13
4847
4867
breast cancer; keratin; nanoparticles; paclitaxel; perfused three-dimensional models; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Survival; Drug Liberation; Female; Gene Expression Regulation, Neoplastic; Humans; Keratins; MCF-7 Cells; Nanoparticles; Paclitaxel; Models, Biological
Foglietta, Federica; Spagnoli, Giulio C; Muraro, Manuele Giuseppe; Ballestri, Marco; Guerrini, Andrea; Ferroni, Claudia; Aluigi, Annalisa; Sotgiu, Giovanna; Varchi, Greta
03A-Articolo su Rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1869099
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