Improving Quality of Life in Older Adults Living at Home by a Moderate Exercise Training

Background: Physical activity is associated with a higher quality of life (QoL) in older adults, but there is no evidence of whether its effects on healthy individuals or individuals with a mild disability performing a medium-intensity exercise program can be assessed. Objective: This randomized controlled trial aims to evaluate whether moderate exercise training can improve QoL, and whether this model is suitable for older adults with mild chronic diseases living in the community. Methods: 120 participants, randomized 1/1 to either perform a physical exercise protocol or to undergo a social program (control group), were recruited in a 12-week randomized controlled trial registered at ClinicalTrials.Gov (NCT03858114). QoL was measured through the Health-Related Quality of Life Survey Short Form - 12 items tool (SF-12). Results: The participants involved in the exercise-training program had a moderate QoL improvement, compared to those involved in cultural activities, who experienced no change or even a worsening of their QoL. However, the between-groups differences did not attain the statistically significant threshold, when globally assessed, F[1, 103] = 2.98, p = .087, nor when the analysis was restricted to the physical (F[1, 103] = 2.78, p = .099) or mental components (F[1, 103] = 3.83, p = .053). Conclusion: Data from this study are not conclusive, although suggestive of possible efficacy. An effort to collect a larger amount of evidence is advisable. Research published only as protocols, not providing final results, might be useful to demonstrate or reject the hypothesis that physical exercise improves QoL in older adults. On a heuristic level, the sum of results that are not conclusive individually might be decisive if meta-analyzed. (Randomized Controlled Blind trial NCT03858114).