In the KEYNOTE-010 study, pembrolizumab improved overall survival (OS) versus docetaxel in patients with previously treated, advanced non‒small-cell lung cancer (NSCLC) with PD-L1 tumor proportion score (TPS) ≥50% and ≥1%. We report 5-year efficacy/safety follow-up for the KEYNOTE-010 study.

Five Year Survival Update From KEYNOTE-010: Pembrolizumab Versus Docetaxel for Previously Treated, Programmed Death-Ligand 1–Positive Advanced NSCLC

Novello, Silvia;
2021-01-01

Abstract

In the KEYNOTE-010 study, pembrolizumab improved overall survival (OS) versus docetaxel in patients with previously treated, advanced non‒small-cell lung cancer (NSCLC) with PD-L1 tumor proportion score (TPS) ≥50% and ≥1%. We report 5-year efficacy/safety follow-up for the KEYNOTE-010 study.
2021
Oct 16
10
1718
1732
PD-L1; chemotherapy; non‒small-cell lung cancer; pembrolizumab
Herbst, Roy S; Garon, Edward B; Kim, Dong-Wan; Cho, Byoung Chul; Gervais, Radj; Perez-Gracia, Jose L; Han, Ji-Youn; Majem, Margarita; Forster, Martin D; Monnet, Isabelle; Novello, Silvia; Gubens, Matthew A; Boyer, Michael; Su, Wu-Chou; Samkari, Ayman; Jensen, Erin H; Kobie, Julie; Piperdi, Bilal; Baas, Paul
File in questo prodotto:
File Dimensione Formato  
PIIS1556086421021729.pdf

Accesso aperto

Tipo di file: PDF EDITORIALE
Dimensione 598.59 kB
Formato Adobe PDF
598.59 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1874424
Citazioni
  • ???jsp.display-item.citation.pmc??? 91
  • Scopus 142
  • ???jsp.display-item.citation.isi??? 125
social impact