Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, Olea europaea L. extract, and fructooligosaccharides, in dogs in advanced CKD stage. Thirty dogs were enrolled in the study; half were administered the new dietary supplementation for 90 days, while the others were used as controls. Hematologic, biochemical, and urinalysis were performed. This novel dietary supplement mainly reported a good control of uremia, phosphate, acid-base balance, blood pressure, inflammation, and oxidative stress in dogs with advanced stages of CKD.

Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress

Martello, Elisa
;
Bisanzio, Donal;Meineri, Giorgia;
2021-01-01

Abstract

Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, Olea europaea L. extract, and fructooligosaccharides, in dogs in advanced CKD stage. Thirty dogs were enrolled in the study; half were administered the new dietary supplementation for 90 days, while the others were used as controls. Hematologic, biochemical, and urinalysis were performed. This novel dietary supplement mainly reported a good control of uremia, phosphate, acid-base balance, blood pressure, inflammation, and oxidative stress in dogs with advanced stages of CKD.
2021
8
11
277
288
https://www.mdpi.com/2306-7381/8/11/277
CKD; ROS; SDMA; diet supplement; dog; serum phosphorus
Martello, Elisa; Perondi, Francesca; Bruni, Natascia; Bisanzio, Donal; Meineri, Giorgia; Lippi, Ilaria
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1894998
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