Patients with post-transplant cytopenias due to poor graft function or primary engraftment failure show poor prognosis with a high mortality rate mainly because of graft versus host disease (GVHD), infection and/or bleeding. Treatment options are scarce and a CD34+ stem cell boost or a second bone marrow transplantation may be required to restore adequate haematopoiesis.
Rescue treatment with eltrombopag in refractory cytopenias after allogeneic stem cell transplantation
Aydin, Semra;Dellacasa, Chiara;Manetta, Sara;Giaccone, Luisa;Bruno, Benedetto;
2020-01-01
Abstract
Patients with post-transplant cytopenias due to poor graft function or primary engraftment failure show poor prognosis with a high mortality rate mainly because of graft versus host disease (GVHD), infection and/or bleeding. Treatment options are scarce and a CD34+ stem cell boost or a second bone marrow transplantation may be required to restore adequate haematopoiesis.
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