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To investigate changes in B cell subsets in relation to disease flares upon initiation of standard therapy (ST) plus belimumab or placebo in patients with systemic lupus erythematosus (SLE).

Early B Cell and Plasma Cell Kinetics Upon Treatment Initiation Portend Flares in Systemic Lupus Erythematosus: A Post-Hoc Analysis of Three Phase III Clinical Trials of Belimumab

Gatto M.
2022-01-01

Abstract

To investigate changes in B cell subsets in relation to disease flares upon initiation of standard therapy (ST) plus belimumab or placebo in patients with systemic lupus erythematosus (SLE).
2022
FRONTIERS IN IMMUNOLOGY
13
1
14
B cells; belimumab; biologics; biomarkers; flares; plasma cells; systemic lupus erythematosus; Antibodies; Monoclonal; Humanized; Complement System Proteins; Humans; Kinetics; Severity of Illness Index; Treatment Outcome; Lupus Erythematosus; Systemic; Plasma Cells
Parodis I.; Gomez A.; Chow J. W.; Borg A.; Lindblom J.; Gatto M.
03A-Articolo su Rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1939351
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