To determine diagnostic accuracy of HLA-B*57:01 testing for prediction of abacavir-induced hypersensitivity and to quantify the clinical benefit of pretreatment screening through a meta-analytic review of published studies.

Diagnostic accuracy of HLA-B*57:01 screening for the prediction of abacavir hypersensitivity and clinical utility of the test: a meta-analytic review

CANONICO, Pier Luigi;GENAZZANI, Armando;
2014-01-01

Abstract

To determine diagnostic accuracy of HLA-B*57:01 testing for prediction of abacavir-induced hypersensitivity and to quantify the clinical benefit of pretreatment screening through a meta-analytic review of published studies.
2014
15
7
963
976
HLA-B*57:01; abacavir hypersensitivity; clinical utility; diagnostic accuracy; meta-analysis; Anti-HIV Agents; Dideoxynucleosides; Drug Hypersensitivity; Genetic Testing; HIV Infections; HLA-B Antigens; Humans; Pharmacogenetics
CARGNIN, Sarah; JOMMI, CLAUDIO; CANONICO, Pier Luigi; GENAZZANI, Armando; TERRAZZINO, SALVATORE
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1953138
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