A chiral sodium glycerophosphate is successfully exploited as a catalyst in the Michael Abstract: A chiral sodium glycerophosphate is successfully exploited as a catalyst in the Michael addition of methyl malonate to a number of chalcones. The reactions supplied the target adducts in satisfactory yields and good enantiomeric excesses. A tentative computational study is presented, aiming to understand the reaction mechanism.

Chiral Sodium Glycerophosphate Catalyst for Enantioselective Michael Reactions of Chalcones

Giovanni Ghigo
First
;
Stefano Dughera
Last
2024-01-01

Abstract

A chiral sodium glycerophosphate is successfully exploited as a catalyst in the Michael Abstract: A chiral sodium glycerophosphate is successfully exploited as a catalyst in the Michael addition of methyl malonate to a number of chalcones. The reactions supplied the target adducts in satisfactory yields and good enantiomeric excesses. A tentative computational study is presented, aiming to understand the reaction mechanism.
2024
29
19
4763
4767
https://www.mdpi.com/1420-3049/29/19/4763
conjugate addition; organocatalyst; chiral catalyst
Giovanni Ghigo, Julia Rivella, Alessio Robiolio Bose, Stefano Dughera
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/2028783
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