Highlights: - Immunologically mediated drug reactions are very heterogeneous clinical syndromes, associated with considerable morbidity and mortality and related to the withdrawal from the market of many pharmaceuticals products - Many studies shown a strong correlation between different HLA alleles and the development of immunoallergic adverse drug reactions - Pharmacogenetic analysis of different HLA alleles will be progressively exploited in everyday clinical activity in order to prevent adverse drug reactions
Pharmacogenetics of immunoallergic adverse drug reactions
Negrini S
2013-01-01
Abstract
Highlights: - Immunologically mediated drug reactions are very heterogeneous clinical syndromes, associated with considerable morbidity and mortality and related to the withdrawal from the market of many pharmaceuticals products - Many studies shown a strong correlation between different HLA alleles and the development of immunoallergic adverse drug reactions - Pharmacogenetic analysis of different HLA alleles will be progressively exploited in everyday clinical activity in order to prevent adverse drug reactions
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