Social Compliance With NPIs, Mobility Patterns, and Reproduction Number: Lessons From COVID-19 in Europe

Non-pharmaceutical interventions (NPIs), such as lockdowns, travel restrictions, and social distancing mandates, play a critical role in controlling the spread of infectious diseases by shaping human mobility patterns. Using COVID-19 as a case study, this research investigates the relationships between NPIs, mobility, and the effective reproduction number (Rt) across 13 European countries. We employ XGBoost regression models to estimate missing mobility data from NPIs and missing Rt values from mobility, achieving high accuracy. Additionally, using clustering techniques, we uncover national distinctions in social compliance. Northern European countries demonstrate higher adherence to NPIs than Southern Europe, which exhibits more variability in response to restrictions. These differences highlight the influence of cultural and social norms on public health outcomes. In general, our analysis reveals a strong correlation between NPIs and mobility reductions, highlighting the immediate impact of restrictions on population movement. However, the relationship between mobility and Rt is weaker and more nuanced, reflecting the time delays involved, as changes in mobility take time to influence transmission rates. These results underscore the interdependence of restrictions, mobility, and disease spread while demonstrating the potential for data-driven approaches to guide policy decisions. Our approach offers valuable insights for optimizing public health strategies and tailoring interventions to diverse cultural contexts during future health crises.