Green synthesis of scalable non-soluble hydrogels: rapid transesterification of maltodextrin with dimethylcarbonate using DABCO/DMSO

This study presents novel synthetic approaches and catalysts to improve selectivity and energy efficiency, leveraging renewable feedstocks. Hydrogels, valued for their dynamic composition and versatile three-dimensional structure, hold significant promise in controlled release systems. Our investigation focuses on the synthesis of water-insoluble crosslinked hydrogels, particularly maltodextrin-based polymers, guided by green chemistry principles. Utilizing organocatalysis, notably 1,4-diazabicyclo[2.2.2]octane, and dimethylcarbonate as environmentally friendly alternatives, we demonstrate a synthesis pathway that minimizes waste and hazardous byproducts. This work aligns with the tenets of green chemistry, promoting sustainable chemistry practices while mitigating environmental impact.