α-Fluoromethyl amides were prepared through the chemoselective nucleophilic addition of fluoromethyl-lithium to isocyanates.
Chemoselective synthesis of α-fluoromethyl amides via the controlled addition of LiCH2F to N-aryl and N-alkyl isocyanates
Nardi, Alberto;Miele, Margherita;Pace, Vittorio
2026-01-01
Abstract
α-Fluoromethyl amides were prepared through the chemoselective nucleophilic addition of fluoromethyl-lithium to isocyanates.
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