Wang and colleagues showed that ctDNA can be detected in plasma up to 3 years prior to clinical diagnosis. The study highlights the need for ultrasensitive and multimodal approaches that integrate the detection of mutations and copy-number changes with advanced computational platforms to deliver effective early-detection strategies.
Detecting Cancer Early with Ultrasensitive Multimodal Liquid Biopsy
Crisafulli, Giovanni;Patelli, Giorgio;Bardelli, AlbertoLast
2025-01-01
Abstract
Wang and colleagues showed that ctDNA can be detected in plasma up to 3 years prior to clinical diagnosis. The study highlights the need for ultrasensitive and multimodal approaches that integrate the detection of mutations and copy-number changes with advanced computational platforms to deliver effective early-detection strategies.
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