Antibodies against human prealbumin (HPA) give a strong immunoperoxidase staining of the A (glucagon) pancreatic cells and of glucagon-, insulin- and gastrin-producing pancreatic tumours. The majority of intestinal and bronchial carcinoids are also reactive. The staining may be related to presence in the C-terminal sequence of HPA of determinants in common with polypeptide (pro-) hormones.
Binding of antibodies against human prealbumin to intestinal and bronchial carcinoids and to pancreatic endocrine tumours. / BUSSOLATI G ;PAPOTTI M ;SAPINO A. - In: VIRCHOWS ARCHIV. B, CELL PATHOLOGY. - ISSN 0340-6075. - 45(1984), pp. 15-22.