Primary murine mixed lymphocyte culture was used to examine the Lyt phenotype of T-lymphocytes producing migration inhibitory factor (MIF) against alloantigens. Experiments with anti-Lyt 1 and anti-Lyt 2 monoclonal antibodies in the presence of rabbit complement showed that both the Lyt 1+ (helper) and Lyt 2+3+ (cytotoxic/suppressor) T cell subpopulations produced MIF after allogeneic stimulation.
Lyt phenotype of T-lymphocytes producing migration inhibitory factor (MIF) in primary murine mixed lymphocyte culture.
GIOVARELLI, Mirella;CAVALLO, Giovanni;LANDOLFO, Santo Giuseppe
1981-01-01
Abstract
Primary murine mixed lymphocyte culture was used to examine the Lyt phenotype of T-lymphocytes producing migration inhibitory factor (MIF) against alloantigens. Experiments with anti-Lyt 1 and anti-Lyt 2 monoclonal antibodies in the presence of rabbit complement showed that both the Lyt 1+ (helper) and Lyt 2+3+ (cytotoxic/suppressor) T cell subpopulations produced MIF after allogeneic stimulation.File in questo prodotto:
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