Membranes of poly(acrylonitrile-co-acrylic acid) made by phase inversion technique in the presence of tetracycline hydrochloride showed molecular recognition behavior towards the template molecule. The interactions of the carboxylic groups of the polymer chain played an important role in the discrimination process. Prolonged washing with distilled water regenerated the membrane without any loss of binding capacity. Chloramphenicol, of similar polarity and fair solubility in water, is recognized less efficiently.

A Molecular imprinted membrane for molecular discrimination of tetracycline hydrochlorid

TROTTA, Francesco;BAGGIANI, Claudio;LUDA DI CORTEMIGLIA, Maria Paola;
2005

Abstract

Membranes of poly(acrylonitrile-co-acrylic acid) made by phase inversion technique in the presence of tetracycline hydrochloride showed molecular recognition behavior towards the template molecule. The interactions of the carboxylic groups of the polymer chain played an important role in the discrimination process. Prolonged washing with distilled water regenerated the membrane without any loss of binding capacity. Chloramphenicol, of similar polarity and fair solubility in water, is recognized less efficiently.
254/1-2
13
19
Molecular imprinting; Molecular recognition; Tetracycline; Membrane; Antibiotic drugs
F. Trotta; C. Baggiani; M.P. Luda; E. Drioli ; T. Massari
File in questo prodotto:
File Dimensione Formato  
JMS 05 13-19 N88.pdf

Accesso riservato

Tipo di file: POSTPRINT (VERSIONE FINALE DELL’AUTORE)
Dimensione 329.13 kB
Formato Adobe PDF
329.13 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/30106
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 73
  • ???jsp.display-item.citation.isi??? 65
social impact