Membranes of poly(acrylonitrile-co-acrylic acid) made by phase inversion technique in the presence of tetracycline hydrochloride showed molecular recognition behavior towards the template molecule. The interactions of the carboxylic groups of the polymer chain played an important role in the discrimination process. Prolonged washing with distilled water regenerated the membrane without any loss of binding capacity. Chloramphenicol, of similar polarity and fair solubility in water, is recognized less efficiently.

A Molecular imprinted membrane for molecular discrimination of tetracycline hydrochlorid

TROTTA, Francesco;BAGGIANI, Claudio;LUDA DI CORTEMIGLIA, Maria Paola;
2005-01-01

Abstract

Membranes of poly(acrylonitrile-co-acrylic acid) made by phase inversion technique in the presence of tetracycline hydrochloride showed molecular recognition behavior towards the template molecule. The interactions of the carboxylic groups of the polymer chain played an important role in the discrimination process. Prolonged washing with distilled water regenerated the membrane without any loss of binding capacity. Chloramphenicol, of similar polarity and fair solubility in water, is recognized less efficiently.
2005
254/1-2
13
19
Molecular imprinting; Molecular recognition; Tetracycline; Membrane; Antibiotic drugs
F. Trotta; C. Baggiani; M.P. Luda; E. Drioli ; T. Massari
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/30106
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