La spasticità: il trattamento farmacologico. L'uso della tossina botulinica e trattamento specifico

Introduction. The spasticity is a complex movement disorders in which several neurophysiological circuits are involved. This complexity added to the rheological muscle’s modifications make it difficult to understand the functional meaning of the symptom. In cerebral palsy, in fact, spasticity can also be seen as positive factors and used in a functional manner. Before choosing a therapeutic strategy it is important to understand the functional meaning of spasticity for that child. Nowadays pharmacological treatments include systemic, intratecal and local approaches. Methods and materials. OUR experience is focused on the use of the botulin toxin. We explain clinical assessment on protocol for post-inoculation on rehabilitative treatment. Results. Results wary depending in the severity of the disability and on the age of patients, on a correct identification of muscles to inoculate, on an adequate dose of toxin and most of all on post-inoculation rehabilitative treatment. Conclusion. In our experience post-inoculation rehabilitative treatment can influence the outcome especially from a functional point of view. Nevertheless, there aren’t enough statistical evidence yet either t confirm or to refute advantage of using BT-A in a cerebral palsy.