We used Y(1)R/LacZ transgenic mice to investigate the interaction between NPY, GABA and Y(1) receptors in the amygdala. Immunolabeling of GABA and NPY positive neurons and histochemical staining of beta-galactosidase revealed NPY and GABA colocalization and close contacts of NPY-positive fibers with GABAergic neurons also expressing the Y(1)R/LacZ transgene.
GABAergic and NPY-Y(1) network in the medial amygdala: a neuroanatomical basis for their functional interaction
OBERTO, Alessandra;PANZICA, Giancarlo;ALTRUDA, Fiorella;EVA, Carola Eugenia
2001-01-01
Abstract
We used Y(1)R/LacZ transgenic mice to investigate the interaction between NPY, GABA and Y(1) receptors in the amygdala. Immunolabeling of GABA and NPY positive neurons and histochemical staining of beta-galactosidase revealed NPY and GABA colocalization and close contacts of NPY-positive fibers with GABAergic neurons also expressing the Y(1)R/LacZ transgene.
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