A series of novel functionalized, water-soluble, pH-unsensitive, highly photostable heptamethine cyanine dyes (HCDs) has been synthesized. The aim of the synthesis was to obtain novel effective probes for fluorescence detection in the near infrared. Synthesis and characterization of a special HCD with large Stokes’ shift (>100 nm), bioconjugation to IgG and effect of pH upon the new structure are presented
Novel Heptametine Cyanine Dyes with Large Stokes' Shift for Biological Applications in the Near Infrared
CAPUTO, Giuseppe;BAROLO, CLAUDIA;VISCARDI, Guido;COLUCCIA, Salvatore
2006-01-01
Abstract
A series of novel functionalized, water-soluble, pH-unsensitive, highly photostable heptamethine cyanine dyes (HCDs) has been synthesized. The aim of the synthesis was to obtain novel effective probes for fluorescence detection in the near infrared. Synthesis and characterization of a special HCD with large Stokes’ shift (>100 nm), bioconjugation to IgG and effect of pH upon the new structure are presented
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J. Fluorescence 16 (2006) 221-225.pdf
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