We report the case of a 63-year-old man with a clearly established diagnosis of hairy cell leukemia, treated with multiple lines of chemotherapy, who complained of localized pain in the left humerus. Radiological findings showed a dystrophic-blastic area within the humeral head. Fine-needle biopsy confirmed the hypothesis of bone involvement of hairy cell leukemia. The patient underwent radiotherapy at a dose of 25 Gy, obtaining a complete clinical response with resolution of pain and a partial recovery of the normal radiological structure of the humerus after 2 months. In addition to the case report, we present a short review of the literature focusing on the role of radiotherapy in this subset of patients.

A case of bone involvement in hairy cell leukemia successfully treated with radiation therapy

FRANCO, Pierfrancesco;FILIPPI, Andrea Riccardo;RICARDI, Umberto
2006

Abstract

We report the case of a 63-year-old man with a clearly established diagnosis of hairy cell leukemia, treated with multiple lines of chemotherapy, who complained of localized pain in the left humerus. Radiological findings showed a dystrophic-blastic area within the humeral head. Fine-needle biopsy confirmed the hypothesis of bone involvement of hairy cell leukemia. The patient underwent radiotherapy at a dose of 25 Gy, obtaining a complete clinical response with resolution of pain and a partial recovery of the normal radiological structure of the humerus after 2 months. In addition to the case report, we present a short review of the literature focusing on the role of radiotherapy in this subset of patients.
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Hairy cell leukemia; Bone involvement; Radiotherapy
Franco, Pierfrancesco; Filippi, Andrea Riccardo; Fornari, A; Marinone, C; Ricardi, Umberto
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/41526
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