Bioactive glasses are used in medical field as bone regenerative materials. They promote the growth of bone tissue on their surface, and establish interconnections in order to form a continuum with the tissue. The bioactivity of this class of materials, immersed in a real or simulated biological medium, is monitored by the ability to form at its surface a layer of Ca-phosphate, which ought to crystallize in the form of either hydroxy-apatite (HA) or hydroxy-carbonate-apatite (HCA). The present contribution deals with the activity/reactivity of some oxidic materials (to be possibly used as bio-active glasses) that: i) have been produced through the conventional elt-quench-grind method; ii) belong to the family of Hench’s Bioglass (H-glass); iii) have been modified, in respect of H-glass composition, by the introduction of variable amounts of Ca-fluoride. In assessing the bioactivity of two families of F-modified glasses, it is herewith shown that the use of some physico-chemical methods, typical of surface chemistry (e.g., surface area determination, IR and Raman vibrational spectroscopic analysis), gives indeed access to what happens at the interface between a complex oxidic material and the surrounding biological medium.
Fluoride-containing bioactive glasses: Some aspects of the reactivity in simulated body solutions
AINA, VALENTINA;MAGNACCA, Giuliana;CERRATO, Giuseppina;BONINO, Francesca Carla;MORTERRA, Claudio
2008-01-01
Abstract
Bioactive glasses are used in medical field as bone regenerative materials. They promote the growth of bone tissue on their surface, and establish interconnections in order to form a continuum with the tissue. The bioactivity of this class of materials, immersed in a real or simulated biological medium, is monitored by the ability to form at its surface a layer of Ca-phosphate, which ought to crystallize in the form of either hydroxy-apatite (HA) or hydroxy-carbonate-apatite (HCA). The present contribution deals with the activity/reactivity of some oxidic materials (to be possibly used as bio-active glasses) that: i) have been produced through the conventional elt-quench-grind method; ii) belong to the family of Hench’s Bioglass (H-glass); iii) have been modified, in respect of H-glass composition, by the introduction of variable amounts of Ca-fluoride. In assessing the bioactivity of two families of F-modified glasses, it is herewith shown that the use of some physico-chemical methods, typical of surface chemistry (e.g., surface area determination, IR and Raman vibrational spectroscopic analysis), gives indeed access to what happens at the interface between a complex oxidic material and the surrounding biological medium.File | Dimensione | Formato | |
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