Aldosterone is produced not only in the adrenal gland but also in other tissues, including the brain, where it plays an important role in the control of blood pressure and water and electrolyte homeostasis. Aldosterone has also been demonstrated to be a major factor in target organ damage independent of its effects on blood pressure. Herein we review the pathophysiology of aldosterone action in the brain and the clinical and experimental studies on the detrimental effects of aldosterone in the brain

Aldosterone as an independent factor in cerebrovascular damage

MULATERO, Paolo;Morello F;VEGLIO, Franco
2008

Abstract

Aldosterone is produced not only in the adrenal gland but also in other tissues, including the brain, where it plays an important role in the control of blood pressure and water and electrolyte homeostasis. Aldosterone has also been demonstrated to be a major factor in target organ damage independent of its effects on blood pressure. Herein we review the pathophysiology of aldosterone action in the brain and the clinical and experimental studies on the detrimental effects of aldosterone in the brain
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Aldosterone; Blood pressure; Brain; End organ damage; Aldosterone; Animals; Blood Pressure; Cerebrovascular Disorders; Disease Models, Animal; Humans; Hypertension; Risk Factors; Stroke; Internal Medicine; Physiology
Mulatero P; Caserta M; Bertello C; Schiavone D; Verhovez A; Giraudo G; Morello F; Veglio F
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/58137
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