The association of human herpesvirus-7 with lung diseases is poorly known, although it has been suggested a role in causing interstitial pneumonia in non-transplant patients and bronchiolitis-obliterans-organizing-pneumonia in lung transplant. No case of acute respiratory distress syndrome associated to human herpesvirus-7 has been reported, while only one case associated with human herpesvirus-6 has been described in an immunocompetent patient. This report describes the identification of human herpesvirus-7 reactivation in an immunocompetent patient with acute respiratory distress syndrome, as evidenced by the increasing viral load in bronchoalveolar lavage, polyneuropathy, histopathological findings, and tissue positivity. Human herpesvirus-7 reactivation in this context could be a consequence of the tissue damage due to the underlying lung disease, rather than the cause, as suggested by the temporal profile of viral load on BAL.

Acute respiratory distress syndrome associated with HHV-7 infection in an immunocompetent patient: a case report

Costa C;BERGALLO, Massimiliano;Solidoro P;CAVALLO, Rossana
2009

Abstract

The association of human herpesvirus-7 with lung diseases is poorly known, although it has been suggested a role in causing interstitial pneumonia in non-transplant patients and bronchiolitis-obliterans-organizing-pneumonia in lung transplant. No case of acute respiratory distress syndrome associated to human herpesvirus-7 has been reported, while only one case associated with human herpesvirus-6 has been described in an immunocompetent patient. This report describes the identification of human herpesvirus-7 reactivation in an immunocompetent patient with acute respiratory distress syndrome, as evidenced by the increasing viral load in bronchoalveolar lavage, polyneuropathy, histopathological findings, and tissue positivity. Human herpesvirus-7 reactivation in this context could be a consequence of the tissue damage due to the underlying lung disease, rather than the cause, as suggested by the temporal profile of viral load on BAL.
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Acute respiratory distress syndrome; Bronchoalveolar lavage; Human herpesvirus-7; Transbronchial biospy
Costa C; Bergallo M; Delsedime L; Solidoro P; Donadio P; Cavallo R.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/65533
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