BACKGROUND: Composite hemangioendothelioma is a rare histopathologic feature, which is part of the hemangioendothelioma family. This is a heterogeneous group of vascular neoplasia with a high tendency to local relapse but a rare predisposition to metastatic spread. Composite hemangioendothelioma mainly affects adults and is usually localized in the distal extremity of the limbs. To date, only 1 case has been detected in the oral cavity. METHODS: A case of composite hemangioendothelioma in a 38-year-old man is reported. The lesion was localized in the left cheek vestibular mucosa. It was surgically excised with a 1-cm safety margin. Reconstruction was performed with a platysma myocutaneous flap. RESULTS: At present, the patient is free from recurrence. The aesthetic and functional outcomes are satisfactory. CONCLUSION: This case demonstrates how a composite hemangioendothelioma histological diagnosis can be difficult to achieve. Furthermore, therapy must be surgical and excision should be wide.

Composite hemangioendothelioma of the oral cavity: case report and review of the literature

FASOLIS, Massimo;GARZINO DEMO, Paolo;BERRONE, Sid
2008-01-01

Abstract

BACKGROUND: Composite hemangioendothelioma is a rare histopathologic feature, which is part of the hemangioendothelioma family. This is a heterogeneous group of vascular neoplasia with a high tendency to local relapse but a rare predisposition to metastatic spread. Composite hemangioendothelioma mainly affects adults and is usually localized in the distal extremity of the limbs. To date, only 1 case has been detected in the oral cavity. METHODS: A case of composite hemangioendothelioma in a 38-year-old man is reported. The lesion was localized in the left cheek vestibular mucosa. It was surgically excised with a 1-cm safety margin. Reconstruction was performed with a platysma myocutaneous flap. RESULTS: At present, the patient is free from recurrence. The aesthetic and functional outcomes are satisfactory. CONCLUSION: This case demonstrates how a composite hemangioendothelioma histological diagnosis can be difficult to achieve. Furthermore, therapy must be surgical and excision should be wide.
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Fasolis M; Iaquinta C; Montesco MC; P. Garzino-Demo; Tosco P; Tanteri G; Bonandini E; Ninfo V; Berrone S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/70109
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