The synthesis of quinolines via Friedländer annulation was carried out in the presence of catalytic amount of o-benzenedisulfonimide as Brønsted acid organocatalyst; the reaction conditions were mild and the yields of the target products were good. The organocatalyst was easily recovered and purified, ready to be used in further reactions
o-Benzenedisulfonimide as a reusable Brønsted acid catalyst for an efficient and facile synthesis of quinolines via Friedländer annulation
BARBERO, Margherita;BAZZI, STEFANO;CADAMURO, Silvano;DUGHERA, Stefano
2010-01-01
Abstract
The synthesis of quinolines via Friedländer annulation was carried out in the presence of catalytic amount of o-benzenedisulfonimide as Brønsted acid organocatalyst; the reaction conditions were mild and the yields of the target products were good. The organocatalyst was easily recovered and purified, ready to be used in further reactions
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