A new method for protecting alcohols as tert-butyl ethers is reported. The reaction is performed in tert-butyl acetate in the presence of a catalytic amount of HClO4. The process is extremely efficient and primary and secondary alcohols as well as diols are protected under very mild conditions. Remarkably, tert-butyl acetate can be easily recovered after the workup of the reaction and recycled.

A New Practical and Efficient Method for Protecting Alcohols as t-Butyl Ethers

BARGE, Alessandro;PRANDI, Cristina;TABASSO, Silvia;VENTURELLO, Paolo
2010

Abstract

A new method for protecting alcohols as tert-butyl ethers is reported. The reaction is performed in tert-butyl acetate in the presence of a catalytic amount of HClO4. The process is extremely efficient and primary and secondary alcohols as well as diols are protected under very mild conditions. Remarkably, tert-butyl acetate can be easily recovered after the workup of the reaction and recycled.
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812
816
Alessandro Barge; Ernesto G. Occhiato; Cristina Prandi; Dina Scarpi; Silvia Tabasso; Paolo Venturello
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/72746
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