Two steps is the rule: A concise synthesis of versatile α′-methoxy-γ-pyrones (see scheme) is described that uses an innovative desymmetrization of α,α′-dimethoxy-γ-pyrone, relying upon conjugate addition of nucleophiles. This new strategy is applied to the preparation of α-methyl- and α-carboxaldehyde-α′-methoxy-γ-pyrones and to a short synthesis of verticipyrone.
A Concise Route to alpha '-Methoxy-gamma-pyrones and Verticipyrone Based Upon the Desymmetrization of alpha,alpha '-Dimethoxy-gamma-pyrone
PRANDI, Cristina;
2010-01-01
Abstract
Two steps is the rule: A concise synthesis of versatile α′-methoxy-γ-pyrones (see scheme) is described that uses an innovative desymmetrization of α,α′-dimethoxy-γ-pyrone, relying upon conjugate addition of nucleophiles. This new strategy is applied to the preparation of α-methyl- and α-carboxaldehyde-α′-methoxy-γ-pyrones and to a short synthesis of verticipyrone.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
11229_ftp.pdf
Open Access dal 13/12/2012
Tipo di file:
POSTPRINT (VERSIONE FINALE DELL’AUTORE)
Dimensione
213.95 kB
Formato
Adobe PDF
|
213.95 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
