A general, one-step procedure for the synthesis of alkyl and aryl alkylcarbamates, by the direct reaction of S-methyl N-alkyl-thiocarbamates with alcohols or phenols in toluene at reflux in the presence of triethylamine, is reported. All the target products were obtained in high yield (15 examples, average yield 94%) and very high purity (>99.2%). The recovery of a co-product of industrial interest, metanethiol, in an amount of one mole for each mole of thiocarbamate, with complete exploitation of the reagent, should also be noted.

An Easy and Efficient One-Step Procedure for the Preparation of Alkyl and Aryl Alkylcarbamates from S-Methyl N-Alkylthiocarbamates

FOCHI, Rita;MAGISTRIS, CLAUDIO
2008

Abstract

A general, one-step procedure for the synthesis of alkyl and aryl alkylcarbamates, by the direct reaction of S-methyl N-alkyl-thiocarbamates with alcohols or phenols in toluene at reflux in the presence of triethylamine, is reported. All the target products were obtained in high yield (15 examples, average yield 94%) and very high purity (>99.2%). The recovery of a co-product of industrial interest, metanethiol, in an amount of one mole for each mole of thiocarbamate, with complete exploitation of the reagent, should also be noted.
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2919
2924
carbamates; thiocarbamates; S; S-dimethyl dithiocarbonate; green chemistry
Degani Iacopo; Fochi Rita; Magistris Claudio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/86632
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