MRI contrast agents are routinely used in clinical settings. Important advances in their design have been attained in the past few years to overcome sensitivity issues and to make possible molecular imaging applications by means of this modality. Besides the sensitivity enhancement of paramagnetic relaxation probes, outstanding results have been obtained in the development of novel classes of frequency-encoding agents such as chemical exchange saturation transfer and hyperpolarized 13C-enriched molecules. © 2011 Elsevier Ltd. All rights reserved.

Contrast agents and mechanisms

DASTRU', Walter;LONGO, DARIO LIVIO;AIME, Silvio
2011

Abstract

MRI contrast agents are routinely used in clinical settings. Important advances in their design have been attained in the past few years to overcome sensitivity issues and to make possible molecular imaging applications by means of this modality. Besides the sensitivity enhancement of paramagnetic relaxation probes, outstanding results have been obtained in the development of novel classes of frequency-encoding agents such as chemical exchange saturation transfer and hyperpolarized 13C-enriched molecules. © 2011 Elsevier Ltd. All rights reserved.
8(2-4)
e109
e115
http://www.sciencedirect.com/science/article/pii/S1740674911000333
Dastrù W; Longo D; Aime S
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/97208
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