Sfoglia per Autore
AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib
2022-01-01 Barbara Buccinnà; Cristina Ramondetti; Marco Piccinini.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety
2022-01-01 Sainas, Stefano; Giorgis, Marta; Circosta, Paola; Poli, Giulio; Alberti, Marta; Passoni, Alice; Gaidano, Valentina; Pippione, Agnese C; Vitale, Nicoletta; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ramondetti, Cristina; Lanno, Alessia; Ferraris, Davide M; Canepa, Barbara; Buccinnà, Barbara; Piccinini, Marco; Rizzi, Menico; Saglio, Giuseppe; Al-Karadaghi, Salam; Boschi, Donatella; Miggiano, Riccardo; Tuccinardi, Tiziano; Lolli, Marco L
Targeting Plasmodium falciparum dihydroorotate dehydrogenase: design, synthesis, co-crystallization and biological evaluation of new 3-hydroxypyrazole scaffold-based inhibitors
2022-01-01 Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Marta Giorgis, Giulio Poli, Tiziano Tuccinardi, Marta Alberti, Riccardo Miggiano, Davide Maria Ferraris, Luca Marchisio, Sandrine Cojean, Efrain Salamanca, Alberto Jose Gimenez, Barbara Buccinnà, Cristina Ramondetti, Marco Piccinini, Marco Lucio Lolli, Donatella Boschi
Targeting Plasmodium falciparum dihydroorotate dehydrogenase: design, synthesis, co-crystallization and biological evaluation of new 3-hydroxypyrazole scaffold-based inhibitors
2022-01-01 Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Marta Giorgis, Giulio Poli, Tiziano Tuccinardi, Marta Alberti, Riccardo Miggiano, Davide Maria Ferraris, Luca Marchisio, Sandrine Cojean, Alberto Gimenéz, Efrain Salamanca, Barbara Buccinnà, Cristina Ramondetti, Marco Piccinini, Marco Lucio Lolli, Donatella Boschi.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety
2021-01-01 Sainas S.; Giorgis M.; Circosta P.; Gaidano V.; Bonanni D.; Pippione A.C.; Bagnati R.; Passoni A.; Qiu Y.; Cojocaru C.F.; Canepa B.; Bona A.; Rolando B.; Mishina M.; Ramondetti C.; Buccinna B.; Piccinini M.; Houshmand M.; Cignetti A.; Giraudo E.; Al-Karadaghi S.; Boschi D.; Saglio G.; Lolli M.L.
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors
2018-01-01 Sainas, Stefano; Pippione, Agnese C; Lupino, Elisa; Giorgis, Marta; Circosta, Paola; Gaidano, Valentina; Goyal, Parveen; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ducime, Alex; Andersson, Mikael; Järvå, Michael; Friemann, Rosmarie; Piccinini, Marco; Ramondetti, Cristina; Buccinnà, Barbara; Al-Karadaghi, Salam; Boschi, Donatella; Saglio, Giuseppe; Lolli, Marco L
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds
2017-01-01 Sainas, Stefano; Pippione, Agnese C.; Giorgis, Marta; Lupino, Elisa; Goyal, Parveen; Ramondetti, Cristina; Buccinnà, Barbara; Piccinini, Marco; Braga, Rodolpho C.; Andrade, Carolina H.; Andersson, Mikael; Moritzer, Ann-Christin; Friemann, Rosmarie; Mensa, Stefano; Al-Kadaraghi, Salam; Boschi, Donatella; Lolli, Marco L
Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases.
2014-01-01 G. De Marco; A. Lomartire; G. Mandili; E. Lupino; B. Buccinnà; C. Ramondetti; C. Moglia; F. Novelli; M. Piccinini; M. Mostert; MT Rinaudo; A. Chiò; A. Calvo
Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27KIP1 as a consequence of c-Abl inhibition
2014-01-01 E. Lupino; C. Ramondetti; B. Buccinnà; M. Piccinini
IκB kinase β is required for activation of NF-κB and AP-1 in CD3/CD28-stimulated primary CD4(+) T cells.
2012-01-01 Lupino E; Ramondetti C; Piccinini M.
Increased cytoplasmic mislocalization of TAR DNA binding protein 43 (TDP-43) in circulating lymphomonocytes of ALS patients recapitulates the major dysfunction featuring motor neurons in the disease.
2011-01-01 De Marco G; Lupino E; Grifoni S; Calvo A; Moglia C; Buccinnà B; Ramondetti C; Lomartire A; Piccinini M; Rinaudo MT;Giordana MT; Chiò A.
Nitrooxyacyl Derivatives of Salicylic Acid: Aspirin-Like Molecules that Covalently Inactivate Cyclooxygenase-1
2011-01-01 C. Cena; P. Tosco; E. Marini; L. Lazzarato; M. Piccinini; C. Ramondetti; E. Lupino; R. Fruttero; A. Gasco.
Novel dysfunctions at the origin of hypomyelination, a feature of Niemann Pick type A
2011-01-01 Buccinnà B; Lomartire A; Ramondetti C; De Marco G; Rinaudo MT; Lupino E; Piccinini M
Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations
2011-01-01 De Marco G; Lupino E; Calvo A; Moglia C; Buccinnà B; Grifoni S; Ramondetti C; Lomartire A; Rinaudo MT; Piccinini M; Giordana MT; Chiò A.
In CD28-costimulated human naïve CD4(+) T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms
2010-01-01 Lupino E; Buccinnà B; Ramondetti C; Lomartire A; De Marco G; Ricotti E; Tovo PA; Rinaudo MT; Piccinini M
N-CAM Dysfunction and Unexpected Accumulation of PSA-NCAM in Brain of Adult-Onset Autosomal-Dominant Leukodystrophy.
2010-01-01 Piccinini Marco; Buccinnà Barbara; De Marco Giovanni; Lupino Elisa; Ramondetti Cristina; Grifoni Silvia; Votta Barbara; Giordana Maria Teresa; Rinaudo Maria Teresa
Dysfunctions in N_CAM and unexpected accumulation of PSA_NCAM in brain of Autosomal dominant adult onset leukodystrophy (ADLD)
2009-01-01 Buccinnà B; De Marco G; Piccinini M; Lupino E; Lomartire A; Ramondetti C; Grifoni S; Giordana MT; Rinaudo MT
The expression pattern of TAR DNA-binding protein 43 (TDP-43) in peripheral blood mononuclear cells (PBMC) in individuals affected by amyotrophific lateral sclerosis (ALS) and their healthy relatives
2009-01-01 De Marco G; Piccinini M; Lupino E; Lomartire A; Buccinnà B; Ramondetti C; Grifoni S; Giordana MT; Rinaudo MT
The molecular basis of the hypomyelination characterizing the brains of sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A
2009-01-01 Buccinnà B; Piccinini M; Prinetti A; Scandroglio F; Prioni S; Valsecchi M; Lupino E; Ramondetti C; De Marco G; Lomartire A; Giordana M T; Sonnino S; Rinaudo M T
Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of niemannpick disease type A
2009-01-01 Barbara Buccinnà; Marco Piccinini; Alessandro Prinetti; Federica Scandroglio; Simona Prioni; Manuela Valsecchi; Barbara Votta; Silvia Grifoni; Elisa Lupino; Cristina Ramondetti; Edward H. Schuchman; Maria Teresa Giordana; Sandro Sonnino; Maria Teresa Rinaudo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib | 2022 | Barbara Buccinnà; Cristina Ramondetti; Marco Piccinini. | |
| Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety | 2022 | Sainas, Stefano; Giorgis, Marta; Circosta, Paola; Poli, Giulio; Alberti, Marta; Passoni, Alice; Gaidano, Valentina; Pippione, Agnese C; Vitale, Nicoletta; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ramondetti, Cristina; Lanno, Alessia; Ferraris, Davide M; Canepa, Barbara; Buccinnà, Barbara; Piccinini, Marco; Rizzi, Menico; Saglio, Giuseppe; Al-Karadaghi, Salam; Boschi, Donatella; Miggiano, Riccardo; Tuccinardi, Tiziano; Lolli, Marco L | |
| Targeting Plasmodium falciparum dihydroorotate dehydrogenase: design, synthesis, co-crystallization and biological evaluation of new 3-hydroxypyrazole scaffold-based inhibitors | 2022 | Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Marta Giorgis, Giulio Poli, Tiziano Tuccinardi, Marta Alberti, Riccardo Miggiano, Davide Maria Ferraris, Luca Marchisio, Sandrine Cojean, Efrain Salamanca, Alberto Jose Gimenez, Barbara Buccinnà, Cristina Ramondetti, Marco Piccinini, Marco Lucio Lolli, Donatella Boschi | |
| Targeting Plasmodium falciparum dihydroorotate dehydrogenase: design, synthesis, co-crystallization and biological evaluation of new 3-hydroxypyrazole scaffold-based inhibitors | 2022 | Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Marta Giorgis, Giulio Poli, Tiziano Tuccinardi, Marta Alberti, Riccardo Miggiano, Davide Maria Ferraris, Luca Marchisio, Sandrine Cojean, Alberto Gimenéz, Efrain Salamanca, Barbara Buccinnà, Cristina Ramondetti, Marco Piccinini, Marco Lucio Lolli, Donatella Boschi. | |
| Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety | 2021 | Sainas S.; Giorgis M.; Circosta P.; Gaidano V.; Bonanni D.; Pippione A.C.; Bagnati R.; Passoni A.; Qiu Y.; Cojocaru C.F.; Canepa B.; Bona A.; Rolando B.; Mishina M.; Ramondetti C.; Buccinna B.; Piccinini M.; Houshmand M.; Cignetti A.; Giraudo E.; Al-Karadaghi S.; Boschi D.; Saglio G.; Lolli M.L. | |
| Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors | 2018 | Sainas, Stefano; Pippione, Agnese C; Lupino, Elisa; Giorgis, Marta; Circosta, Paola; Gaidano, Valentina; Goyal, Parveen; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ducime, Alex; Andersson, Mikael; Järvå, Michael; Friemann, Rosmarie; Piccinini, Marco; Ramondetti, Cristina; Buccinnà, Barbara; Al-Karadaghi, Salam; Boschi, Donatella; Saglio, Giuseppe; Lolli, Marco L | |
| Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds | 2017 | Sainas, Stefano; Pippione, Agnese C.; Giorgis, Marta; Lupino, Elisa; Goyal, Parveen; Ramondetti, Cristina; Buccinnà, Barbara; Piccinini, Marco; Braga, Rodolpho C.; Andrade, Carolina H.; Andersson, Mikael; Moritzer, Ann-Christin; Friemann, Rosmarie; Mensa, Stefano; Al-Kadaraghi, Salam; Boschi, Donatella; Lolli, Marco L | |
| Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases. | 2014 | G. De Marco; A. Lomartire; G. Mandili; E. Lupino; B. Buccinnà; C. Ramondetti; C. Moglia; F. Novelli; M. Piccinini; M. Mostert; MT Rinaudo; A. Chiò; A. Calvo | |
| Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27KIP1 as a consequence of c-Abl inhibition | 2014 | E. Lupino; C. Ramondetti; B. Buccinnà; M. Piccinini | |
| IκB kinase β is required for activation of NF-κB and AP-1 in CD3/CD28-stimulated primary CD4(+) T cells. | 2012 | Lupino E; Ramondetti C; Piccinini M. | |
| Increased cytoplasmic mislocalization of TAR DNA binding protein 43 (TDP-43) in circulating lymphomonocytes of ALS patients recapitulates the major dysfunction featuring motor neurons in the disease. | 2011 | De Marco G; Lupino E; Grifoni S; Calvo A; Moglia C; Buccinnà B; Ramondetti C; Lomartire A; Piccinini M; Rinaudo MT;Giordana MT; Chiò A. | |
| Nitrooxyacyl Derivatives of Salicylic Acid: Aspirin-Like Molecules that Covalently Inactivate Cyclooxygenase-1 | 2011 | C. Cena; P. Tosco; E. Marini; L. Lazzarato; M. Piccinini; C. Ramondetti; E. Lupino; R. Fruttero; A. Gasco. | |
| Novel dysfunctions at the origin of hypomyelination, a feature of Niemann Pick type A | 2011 | Buccinnà B; Lomartire A; Ramondetti C; De Marco G; Rinaudo MT; Lupino E; Piccinini M | |
| Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations | 2011 | De Marco G; Lupino E; Calvo A; Moglia C; Buccinnà B; Grifoni S; Ramondetti C; Lomartire A; Rinaudo MT; Piccinini M; Giordana MT; Chiò A. | |
| In CD28-costimulated human naïve CD4(+) T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms | 2010 | Lupino E; Buccinnà B; Ramondetti C; Lomartire A; De Marco G; Ricotti E; Tovo PA; Rinaudo MT; Piccinini M | |
| N-CAM Dysfunction and Unexpected Accumulation of PSA-NCAM in Brain of Adult-Onset Autosomal-Dominant Leukodystrophy. | 2010 | Piccinini Marco; Buccinnà Barbara; De Marco Giovanni; Lupino Elisa; Ramondetti Cristina; Grifoni Silvia; Votta Barbara; Giordana Maria Teresa; Rinaudo Maria Teresa | |
| Dysfunctions in N_CAM and unexpected accumulation of PSA_NCAM in brain of Autosomal dominant adult onset leukodystrophy (ADLD) | 2009 | Buccinnà B; De Marco G; Piccinini M; Lupino E; Lomartire A; Ramondetti C; Grifoni S; Giordana MT; Rinaudo MT | |
| The expression pattern of TAR DNA-binding protein 43 (TDP-43) in peripheral blood mononuclear cells (PBMC) in individuals affected by amyotrophific lateral sclerosis (ALS) and their healthy relatives | 2009 | De Marco G; Piccinini M; Lupino E; Lomartire A; Buccinnà B; Ramondetti C; Grifoni S; Giordana MT; Rinaudo MT | |
| The molecular basis of the hypomyelination characterizing the brains of sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A | 2009 | Buccinnà B; Piccinini M; Prinetti A; Scandroglio F; Prioni S; Valsecchi M; Lupino E; Ramondetti C; De Marco G; Lomartire A; Giordana M T; Sonnino S; Rinaudo M T | |
| Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of niemannpick disease type A | 2009 | Barbara Buccinnà; Marco Piccinini; Alessandro Prinetti; Federica Scandroglio; Simona Prioni; Manuela Valsecchi; Barbara Votta; Silvia Grifoni; Elisa Lupino; Cristina Ramondetti; Edward H. Schuchman; Maria Teresa Giordana; Sandro Sonnino; Maria Teresa Rinaudo |
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