Sfoglia per Autore
DegraderTCM: A Computationally Sparing Approach for Predicting Ternary Degradation Complexes
2024-01-01 Rossetti P.; Apprato G.; Caron G.; Ermondi G.; Rossi Sebastiano M.
Exploring the chemical space of orally bioavailable PROTACs
2024-01-01 Apprato G.; Poongavanam V.; Garcia Jimenez D.; Atilaw Y.; Erdelyi M.; Ermondi G.; Caron G.; Kihlberg J.
Conformational Sampling Deciphers the Chameleonic Properties of a VHL-Based Degrader
2023-01-01 Ermondi, Giuseppe; Jimenez, Diego Garcia; Rossi Sebastiano, Matteo; Kihlberg, Jan; Caron, Giulia
Deleterious, protein-altering variants in the transcriptional coregulator ZMYM3 in 27 individuals with a neurodevelopmental delay phenotype
2023-01-01 Hiatt, Susan M; Trajkova, Slavica; Sebastiano, Matteo Rossi; Partridge, E Christopher; Abidi, Fatima E; Anderson, Ashlyn; Ansar, Muhammad; Antonarakis, Stylianos E; Azadi, Azadeh; Bachmann-Gagescu, Ruxandra; Bartuli, Andrea; Benech, Caroline; Berkowitz, Jennifer L; Betti, Michael J; Brusco, Alfredo; Cannon, Ashley; Caron, Giulia; Chen, Yanmin; Cochran, Meagan E; Coleman, Tanner F; Crenshaw, Molly M; Cuisset, Laurence; Curry, Cynthia J; Darvish, Hossein; Demirdas, Serwet; Descartes, Maria; Douglas, Jessica; Dyment, David A; Elloumi, Houda Zghal; Ermondi, Giuseppe; Faoucher, Marie; Farrow, Emily G; Felker, Stephanie A; Fisher, Heather; Hurst, Anna C E; Joset, Pascal; Kelly, Melissa A; Kmoch, Stanislav; Leadem, Benjamin R; Lyons, Michael J; Macchiaiolo, Marina; Magner, Martin; Mandrile, Giorgia; Mattioli, Francesca; McEown, Megan; Meadows, Sarah K; Medne, Livija; Meeks, Naomi J L; Montgomery, Sarah; Napier, Melanie P; Natowicz, Marvin; Newberry, Kimberly M; Niceta, Marcello; Noskova, Lenka; Nowak, Catherine B; Noyes, Amanda G; Osmond, Matthew; Prijoles, Eloise J; Pugh, Jada; Pullano, Verdiana; Quélin, Chloé; Rahimi-Aliabadi, Simin; Rauch, Anita; Redon, Sylvia; Reymond, Alexandre; Schwager, Caitlin R; Sellars, Elizabeth A; Scheuerle, Angela E; Shukarova-Angelovska, Elena; Skraban, Cara; Stolerman, Elliot; Sullivan, Bonnie R; Tartaglia, Marco; Thiffault, Isabelle; Uguen, Kevin; Umaña, Luis A; van Bever, Yolande; van der Crabben, Saskia N; van Slegtenhorst, Marjon A; Waisfisz, Quinten; Washington, Camerun; Rodan, Lance H; Myers, Richard M; Cooper, Gregory M
High-throughput and reliable assessments of the ionization constant of monoprotic organic acids through an arginine based mixed mode HPLC
2023-01-01 Russo G.; Kajtazi A.; Vallaro M.; Surmont P.; Ermondi G.; Anderson S.; Grumetto L.; Caron G.; Lynen F.
The Quest for Oral PROTAC drugs: Evaluating the Weaknesses of the Screening Pipeline
2023-01-01 Apprato, Giulia; Ermondi, Giuseppe; Caron, Giulia
Chamelogk: A Chromatographic Chameleonicity Quantifier to Design Orally Bioavailable Beyond-Rule-of-5 Drugs
2023-01-01 GARCÍA JIMÉNEZ DIEGO; Vallaro Maura; Rossi Sebastiano Matteo; Apprato Giulia; D'Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia
In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor
2023-01-01 Apprato Giulia; D’Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia
Ionization and lipophilicity in nonpolar media mimicking the cell membrane interior
2023-01-01 Vallaro, Maura; Ermondi, Giuseppe; Saame, Jaan; Leito, Ivo; Caron, Giulia
Front cover: "Cystic Fibrosis Mucus Model to Design More Efficient Drug Therapies" (Molecular Pharmaceutics 02/2022)
2022-01-01 Cosmin Butnarasu, Giulia Caron, Daniela Pacheco, Paola Petrini, Sonja Visentin
Application of the anthraquinone drug rhein as an axial ligand in bifunctional Pt(IV) complexes to obtain antiproliferative agents against human glioblastoma cells
2022-01-01 Gabano, Elisabetta; Gariboldi, Marzia Bruna; Caron, Giulia; Ermondi, Giuseppe; Marras, Emanuela; Vallaro, Maura; Ravera, Mauro
Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies
2022-01-01 Rossi Sebastiano, Matteo; Ermondi, Giuseppe; Sato, Kai; Otomo, Asako; Hadano, Shinji; Caron, Giulia
AI-based protein structure databases have the potential to accelerate rare diseases research: AlphaFoldDB and the case of IAHSP/Alsin
2022-01-01 Rossi Sebastiano M.; Ermondi G.; Hadano S.; Caron G.
Designing Soluble PROTACs: Strategies and Preliminary Guidelines
2022-01-01 Diego García Jiménez; Matteo Rossi Sebastiano; Maura Vallaro; Valentina Mileo; Daniela Pizzirani; Elisa Moretti; Giuseppe Ermondi; Giulia Caron
Refinement of Computational Access to Molecular Physicochemical Properties: From Ro5 to bRo5
2022-01-01 Rossi Sebastiano, Matteo; Garcia Jimenez, Diego; Vallaro, Maura; Caron, Giulia; Ermondi, Giuseppe
Dall’intelligenza artificiale nuove prospettive per la ricerca sulle malattie rare
2022-01-01 Matteo Rossi Sebastiano; Giuseppe Ermondi; Giulia Caron; Adriana Riccomagno
Managing Experimental 3D Structures in the Beyond-Rule-of-5 Chemical Space: The Case of Rifampicin
2021-01-01 Ermondi, Giuseppe; Lavore, Francesca; Vallaro, Maura; Tiana, Guido; Vasile, Francesca; Caron, Giulia
Permeability prediction in the beyond-Rule-of 5 chemical space: Focus on cyclic hexapeptides
2021-01-01 Digiesi, Vito; de la Oliva Roque, Víctor; Vallaro, Maura; Caron, Giulia; Ermondi, Giuseppe
Pt(iv) complexes based on cyclohexanediamines and the histone deacetylase inhibitor 2-(2-propynyl)octanoic acid: synthesis, characterization, cell penetration properties and antitumor activity
2021-01-01 Gabano E.; Rangone B.; Perin E.; Caron G.; Ermondi G.; Vallaro M.; Gandin V.; Marzano C.; Barbanente A.; Margiotta N.; Ravera M.
PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery
2021-01-01 Giuseppe Ermondi, Diego Garcia Jimenez, Giulia Caron
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| DegraderTCM: A Computationally Sparing Approach for Predicting Ternary Degradation Complexes | 2024 | Rossetti P.; Apprato G.; Caron G.; Ermondi G.; Rossi Sebastiano M. | |
| Exploring the chemical space of orally bioavailable PROTACs | 2024 | Apprato G.; Poongavanam V.; Garcia Jimenez D.; Atilaw Y.; Erdelyi M.; Ermondi G.; Caron G.; Kihlberg J. | |
| Conformational Sampling Deciphers the Chameleonic Properties of a VHL-Based Degrader | 2023 | Ermondi, Giuseppe; Jimenez, Diego Garcia; Rossi Sebastiano, Matteo; Kihlberg, Jan; Caron, Giulia | |
| Deleterious, protein-altering variants in the transcriptional coregulator ZMYM3 in 27 individuals with a neurodevelopmental delay phenotype | 2023 | Hiatt, Susan M; Trajkova, Slavica; Sebastiano, Matteo Rossi; Partridge, E Christopher; Abidi, Fatima E; Anderson, Ashlyn; Ansar, Muhammad; Antonarakis, Stylianos E; Azadi, Azadeh; Bachmann-Gagescu, Ruxandra; Bartuli, Andrea; Benech, Caroline; Berkowitz, Jennifer L; Betti, Michael J; Brusco, Alfredo; Cannon, Ashley; Caron, Giulia; Chen, Yanmin; Cochran, Meagan E; Coleman, Tanner F; Crenshaw, Molly M; Cuisset, Laurence; Curry, Cynthia J; Darvish, Hossein; Demirdas, Serwet; Descartes, Maria; Douglas, Jessica; Dyment, David A; Elloumi, Houda Zghal; Ermondi, Giuseppe; Faoucher, Marie; Farrow, Emily G; Felker, Stephanie A; Fisher, Heather; Hurst, Anna C E; Joset, Pascal; Kelly, Melissa A; Kmoch, Stanislav; Leadem, Benjamin R; Lyons, Michael J; Macchiaiolo, Marina; Magner, Martin; Mandrile, Giorgia; Mattioli, Francesca; McEown, Megan; Meadows, Sarah K; Medne, Livija; Meeks, Naomi J L; Montgomery, Sarah; Napier, Melanie P; Natowicz, Marvin; Newberry, Kimberly M; Niceta, Marcello; Noskova, Lenka; Nowak, Catherine B; Noyes, Amanda G; Osmond, Matthew; Prijoles, Eloise J; Pugh, Jada; Pullano, Verdiana; Quélin, Chloé; Rahimi-Aliabadi, Simin; Rauch, Anita; Redon, Sylvia; Reymond, Alexandre; Schwager, Caitlin R; Sellars, Elizabeth A; Scheuerle, Angela E; Shukarova-Angelovska, Elena; Skraban, Cara; Stolerman, Elliot; Sullivan, Bonnie R; Tartaglia, Marco; Thiffault, Isabelle; Uguen, Kevin; Umaña, Luis A; van Bever, Yolande; van der Crabben, Saskia N; van Slegtenhorst, Marjon A; Waisfisz, Quinten; Washington, Camerun; Rodan, Lance H; Myers, Richard M; Cooper, Gregory M | |
| High-throughput and reliable assessments of the ionization constant of monoprotic organic acids through an arginine based mixed mode HPLC | 2023 | Russo G.; Kajtazi A.; Vallaro M.; Surmont P.; Ermondi G.; Anderson S.; Grumetto L.; Caron G.; Lynen F. | |
| The Quest for Oral PROTAC drugs: Evaluating the Weaknesses of the Screening Pipeline | 2023 | Apprato, Giulia; Ermondi, Giuseppe; Caron, Giulia | |
| Chamelogk: A Chromatographic Chameleonicity Quantifier to Design Orally Bioavailable Beyond-Rule-of-5 Drugs | 2023 | GARCÍA JIMÉNEZ DIEGO; Vallaro Maura; Rossi Sebastiano Matteo; Apprato Giulia; D'Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia | |
| In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor | 2023 | Apprato Giulia; D’Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia | |
| Ionization and lipophilicity in nonpolar media mimicking the cell membrane interior | 2023 | Vallaro, Maura; Ermondi, Giuseppe; Saame, Jaan; Leito, Ivo; Caron, Giulia | |
| Front cover: "Cystic Fibrosis Mucus Model to Design More Efficient Drug Therapies" (Molecular Pharmaceutics 02/2022) | 2022 | Cosmin Butnarasu, Giulia Caron, Daniela Pacheco, Paola Petrini, Sonja Visentin | |
| Application of the anthraquinone drug rhein as an axial ligand in bifunctional Pt(IV) complexes to obtain antiproliferative agents against human glioblastoma cells | 2022 | Gabano, Elisabetta; Gariboldi, Marzia Bruna; Caron, Giulia; Ermondi, Giuseppe; Marras, Emanuela; Vallaro, Maura; Ravera, Mauro | |
| Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies | 2022 | Rossi Sebastiano, Matteo; Ermondi, Giuseppe; Sato, Kai; Otomo, Asako; Hadano, Shinji; Caron, Giulia | |
| AI-based protein structure databases have the potential to accelerate rare diseases research: AlphaFoldDB and the case of IAHSP/Alsin | 2022 | Rossi Sebastiano M.; Ermondi G.; Hadano S.; Caron G. | |
| Designing Soluble PROTACs: Strategies and Preliminary Guidelines | 2022 | Diego García Jiménez; Matteo Rossi Sebastiano; Maura Vallaro; Valentina Mileo; Daniela Pizzirani; Elisa Moretti; Giuseppe Ermondi; Giulia Caron | |
| Refinement of Computational Access to Molecular Physicochemical Properties: From Ro5 to bRo5 | 2022 | Rossi Sebastiano, Matteo; Garcia Jimenez, Diego; Vallaro, Maura; Caron, Giulia; Ermondi, Giuseppe | |
| Dall’intelligenza artificiale nuove prospettive per la ricerca sulle malattie rare | 2022 | Matteo Rossi Sebastiano; Giuseppe Ermondi; Giulia Caron; Adriana Riccomagno | |
| Managing Experimental 3D Structures in the Beyond-Rule-of-5 Chemical Space: The Case of Rifampicin | 2021 | Ermondi, Giuseppe; Lavore, Francesca; Vallaro, Maura; Tiana, Guido; Vasile, Francesca; Caron, Giulia | |
| Permeability prediction in the beyond-Rule-of 5 chemical space: Focus on cyclic hexapeptides | 2021 | Digiesi, Vito; de la Oliva Roque, Víctor; Vallaro, Maura; Caron, Giulia; Ermondi, Giuseppe | |
| Pt(iv) complexes based on cyclohexanediamines and the histone deacetylase inhibitor 2-(2-propynyl)octanoic acid: synthesis, characterization, cell penetration properties and antitumor activity | 2021 | Gabano E.; Rangone B.; Perin E.; Caron G.; Ermondi G.; Vallaro M.; Gandin V.; Marzano C.; Barbanente A.; Margiotta N.; Ravera M. | |
| PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery | 2021 | Giuseppe Ermondi, Diego Garcia Jimenez, Giulia Caron |
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