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Human cytomegalovirus infection triggers a paracrine senescence loop in renal epithelial cells 2024 Raviola, Stefano; Griffante, Gloria; Iannucci, Andrea; Chandel, Shikha; Lo Cigno, Irene; Lacarbonara, Davide; Caneparo, Valeria; Pasquero, Selina; Favero, Francesco; Corà, Davide; Trisolini, Elena; Boldorini, Renzo; Cantaluppi, Vincenzo; Landolfo, Santo; Gariglio, Marisa; De Andrea, Marco
PAD-mediated citrullination is a novel candidate diagnostic marker and druggable target for HPV-associated cervical cancer 2024 Camilla Albano, Matteo Biolatti, Jasenka Mazibrada, Selina Pasquero, Francesca Gugliesi, Irene Lo Cigno, Federica Calati, Greta Bajetto, Giuseppe Riva , Gloria Griffante, Santo Landolfo, Marisa Gariglio, Marco De Andrea, Valentina Dell'Oste
Exploiting lipid metabolism by HSV-1: a challenge to rethink new therapies for Alzheimer's disease. 2023 Camilla Albano, Selina Pasquero, Linda Trifirò, Francesca Gugliesi, Gloria Griffante, Greta Bajetto, Weronika Hewelt-Belka, Erika Mina, Paolo Porporato, Dana M. Cairns, David L. Kaplan, Adam Mullis, Santo Landolfo, Marco De Andrea, Valentina Dell’Oste, Matteo Biolatti
IL-6-mediated paracrine senescence drives the intercellular communication within the HCMV microenvironment in renal epithelial cells 2023 Raviola S, Iannucci A, Caneparo V, Lacarbonara D, Castiglioni F, Lo Cigno I, Favero F, Corà D, Cantaluppi V, Landolfo S, Gariglio M, De Andrea M.
Exploiting lipid metabolism by HSV-1 – a challenge to rethink new therapies for Alzheimer's disease 2023 L. Trifirò, C. Albano, S. Pasquero, F. Gugliesi, G. Griffante, G. Bajetto, W. Hewelt-Belka, E. Mina, P. Porporato, D. Cairns, D. Kaplan, A. Mullis, S. Landolfo, M. De Andrea, Valentina Dell’Oste, M. Biolatti
Herpesvirus-mediated protein citrullination as a new target for antiviral therapy 2023 Selina Pasquero, Francesca Gugliesi, Gloria Griffante, Valentina Dell’Oste, Matteo Biolatti, Camilla Albano, Greta Bajetto, Paul R. Thompson, Sen Sudeshna, Santo Landolfo, Marco De Andrea
Exploiting lipid metabolism by HSV-1: a challenge to rethink new therapies for Alzheimer’s disease 2023 L. Trifirò, C. Albano, S. Pasquero, F. Gugliesi, G. Bajetto, W. Hewelt-Belka, E. Mina, P. Porporato, D. Cairns, D. Kaplan, A. Mullis, S. Landolfo, M. De Andrea, V. Dell’Oste, M. Biolatti
Exploiting Lipid Metabolism by HSV-1: a Challenge to Rethink New Therapies for Alzheimer’s Disease 2023 Camilla Albano, Selina Pasquero, Linda Trifirò, Gloria Griffante, Francesca Gugliesi, Greta Bajetto, Weronika Hewelt- Belka, Erica Mina, Paolo Porporato, Adam Mullis, Dana Cairns, David Kaplan, Santo Landolfo, Marco De Andrea, Valentina Dell’Oste, Matteo Biolatti
Exploiting lipid metabolism by HSV-1: a challenge to rethink new therapies for Alzheimer’s disease. 2023 LINDA TRIFIRÒ, CAMILLA ALBANO, SELINA PASQUERO, FRANCESCA GUGLIESI, GRETA BAJETTO, WERONIKA HEWELT-BELKA, ERICA MINA, PAOLO PORPORATO, DANA CAIRNS, DAVID KAPLAN, ADAM MULLIS, SANTO LANDOLFO, MARCO DE ANDREA, VALENTINA DELL’OSTE, MATTEO BIOLATTI
HSV-1-induced PAD-mediated Citrullination as a New Target for Antiviral Therapy 2023 Camilla Albano, Selina Pasquero, Francesca Gugliesi, Gloria Griffante, Qiao Yang, Valentina Dell’Oste, Matteo Biolatti, Greta Bajetto, Linda Trifirò, Bianca Brugo, Paul R. Thompson, Sen Sudeshna, Santo Landolfo, Marco De Andrea
HSV-1-induced PAD-mediated Citrullination as a New Target for Antiviral Therapy 2023 Camilla Albano, Selina Pasquero, Francesca Gugliesi, Gloria Griffante, Qiao Yang, Valentina Dell’Oste, Matteo Biolatti, Greta Bajetto, Linda Trifirò, Bianca Brugo, Paul Thompson, Sen Sudeshna, Santo Landolfo, Marco De Andrea
Novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2 2023 S. Pasquero, F. Gugliesi, G. Griffante, Valentina Dell’Oste, M. Biolatti, C. Albano, G. Bajetto, S. Delbue, L. Signorini, M. Dolci, S. Landolfo, M. De Andrea
Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors 2023 Pasquero, Selina; Gugliesi, Francesca; Biolatti, Matteo; Dell'Oste, Valentina; Albano, Camilla; Bajetto, Greta; Griffante, Gloria; Trifirò, Linda; Brugo, Bianca; Raviola, Stefano; Lacarbonara, Davide; Yang, Qiao; Sudeshna, Sen; Barasa, Leonard; Haniff, Hafeez; Thompson, Paul R; Landolfo, Santo; De Andrea, Marco
NOVEL ANTIVIRAL ACTIVITY OF PADS INHIBITORS AGAINST HUMAN BETA-CORONAVIRUSES SARS-COV-2 AND HCOV-OC43 2022 Selina Pasquero, Gloria Griffante, Francesca Gugliesi, Matteo Biolatti, Camilla Albano, Sergio Fernando Castillo Pacheco, Greta Bajetto, Valentina Dell’Oste, Serena Delbue, Silvia Parapini, Santo Landolfo, Marco De Andrea
Citrullination upon viral infection: a new strategy for host-targeting antivirals drugs 2022 Selina Pasquero, Gloria Griffante, Francesca Gugliesi, Matteo Biolatti, Camilla Albano, Greta Bajetto, Valentina Dell’Oste, Paul R. Thompson, Sudeshna Sen, Serena Delbue, Silvia Parapini, Maria Dolci, Santo Landolfo, Marco De Andrea
IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection [*Valentina Dell'Oste, *Matteo Biolatti, co-corresponding authors] 2022 Gloria Griffante, Weronika Hewelt-Belka, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Sergio Fernando Castillo Pacheco, Greta Bajetto, Paolo Ettore Porporato, Erica Mina, Marta Vallino, Christian Krapp , Martin Roelsgaard Jakobsen , John Purdy , Jens von Einem, Santo Landolfo, Valentina Dell'Oste, Matteo Biolatti
IFI16 Impacts Metabolic Reprogramming During Human Cytomegalovirus Infection 2022 Matteo Biolatti, Gloria Griffante, Weronika Hewelt-Belka, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Sergio Fernando Castillo Pacheco, Greta Bajetto, Paolo Ettore Porporato, Erica Mina, Marta Vallino, Christian Krapp, Martin Jakobsen, John Purdy, Jens von Einem, Santo Landolfo, Valentina Dell’Oste
IFI16 impacts metabolic reprogramming during human cytomegalovirus infection 2022 Griffante Gloria, Hewelt-Belka Weronika, Albano Camilla, Gugliesi Francesca, Pasquero Selina, Castillo Pacheco Sergio F., Bajetto Greta, Trifiro' Linda, Porporato Paolo E., Mina Erica, Vallino Marta, Krapp Christian, Jakobsen Martin R., Purdy John, Von Einem Jens, Landolfo Santo, Dell'oste Valentina, Biolatti Matteo
IFI16 IMPACTS METABOLIC REPROGRAMMING DURING HUMAN CYTOMEGALOVIRUS INFECTION 2022 Gloria Griffante, Weronika Hewelt-Belka, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Greta Bajetto, Paolo Ettore Porporato, Erica Mina, Marta Vallino, Martin Jakobsen, John Purdy, Jens von Einem, Santo Landolfo, Matteo Biolatti, Valentina Dell’Oste
Characterization of citrullination during infection with DNA and RNA viruses: a new strategy for host-targeting antivirals drugs 2022 Selina Pasquero, Gloria Griffante, Francesca Gugliesi, Matteo Biolatti, Camilla Albano, Greta Bajetto, Valentina Dell'Oste, Paul R Thompson, Sudeshna Sen, Serena Delbue, Silvia Parapini, Maria Dolci, Santo Landolfo, Marco De Andrea
Novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2 2022 Pasquero, Selina; Gugliesi, Francesca; Griffante, Gloria; Dell’Oste, Valentina; Biolatti, Matteo; Albano, Camilla; Bajetto, Greta; Delbue, Serena; Signorini, Lucia; Dolci, Maria; Landolfo, Santo; De Andrea, Marco
50° Congresso Nazionale della Società Italiana di Microbiologia 2022 Albano Camilla, Biolatti Matteo, Mazibrada Jasenka, Pasquero Selina, Gugliesi Francesca, Griffante Gloria, Lo Cigno Irene, Cat Genova Elena, Bajetto Greta, Landolfo Santo, Gariglio Marisa, De Andrea Marco, Dell'Oste Valentina
Strigolactone analogs are promising antiviral agents against Herpesviruses 2021 Matteo Biolatti, Marco Blangetti, Giulia D’Arrigo, Francesca Spyrakis, Paola Cappello, Camilla Albano, Sergio Fernando Castillo Pacheco, Santo Landolfo, Cristina Prandi, Marco De Andrea, Valentina Dell’Oste
Targeting PAD-mediated citrullination to treat human papillomavirus infections 2021 Camilla Albano, Matteo Biolatti, Selina Pasquero, Francesca Gugliesi, Sergio Fernando Castillo Pacheco, Gloria Griffante, Irene Lo Cigno, Marisa Gariglio, Marco De Andrea, Santo Landolfo, Jasenka Mazibrada, Valentina Dell’Oste
NOVEL ANTIVIRAL ACTIVITY OF PADs INHIBITORS AGAINST BETA-CORONAVIRUSES SARS-CoV-2 AND HCoV-OC43 2021 Selina pasquero, Gloria Griffante, Francesca Gugliesi, Matteo Biolatti, Camilla Albano, Sergio Fernando Castillo Pacheco, Greta Bajetto, Valentina Dell’Oste, Serena Del Bue, Silvia Parapini, Santo Landolfo, Marco De Andrea.
HPV meets APOBEC: New players in head and neck cancer [*Biolatti M, Dell'Oste V* co-last authors]. 2021 Riva G.; Albano C.; Gugliesi F.; Pasquero S.; Pacheco S.F.C.; Pecorari G.; Landolfo S.; Biolatti M.; Dell'Oste V.
Targeting PAD-mediated citrullination to treat human papillomavirus infections 2021 CAMILLA ALBANO, MATTEO BIOLATTI, SELINA PASQUERO, FRANCESCA GUGLIESI, SERGIO F. CASTILLO PACHECO, GLORIA GRIFFANTE, ELENA CAT GENOVA, IRENE LO CIGNO, MARISA GARIGLIO, MARCO DE ANDREA, SANTO LANDOLFO, JASENKA MAZIBRADA, VALENTINA DELL’OSTE
IFI16 is a Negative Regulator of Glucose and Cellular Lipid Metabolism during Human Cytomegalovirus Infection 2021 Matteo Biolatti, Gloria Griffante, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Sergio Castillo Pacheco, Paolo Porporato, Erica Mina, Weronika Hewelt-Belka, Marta Vallino, Christian Krapp, Martin Jakobsen, John Purdy, Santo Landolfo, Valentina Dell’Oste
Human cytomegalovirus-induced host protein citrullination is crucial for viral replication 2021 Griffante G.; Gugliesi F.; Pasquero S.; Dell'Oste V.; Biolatti M.; Salinger A.J.; Mondal S.; Thompson P.R.; Weerapana E.; Lebbink R.J.; Soppe J.A.; Stamminger T.; Girault V.; Pichlmair A.; Oroszlan G.; Coen D.M.; De Andrea M.; Landolfo S.
IFI16 impacts metabolic reprogramming during human cytomegalovirus infection 2021 GLORIA GRIFFANTE, WERONIKA HEWELT-BELKA, CAMILLA ALBANO, FRANCESCA GUGLIESI, SELINA PASQUERO, SERGIO F. CASTILLO PACHECO, GRETA BAJETTO, PAOLO E. PORPORATO, ERICA MINA, MARTA VALLINO, CHRISTIAN KRAPP, MARTIN JAKOBSEN, JOHN PURDY, SANTO LANDOLFO, VALENTINA DELL’OSTE, MATTEO BIOLATTI
45th International Herpesvirus Workshop 2021 SELINA PASQUERO, GLORIA GRIFFANTE, FRANCESCA GUGLIESI, MATTEO BIOLATTI, CAMILLA ALBANO, SERGIO FERNANDO CASTILLO PACHECO, MARCO DE ANDREA, VALENTINA DELL’OSTE, SANTO LANDOLFO.
Strigolactone analogs are promising antiviral agents for the treatment of human cytomegalovirus infection 2021 MATTEO BIOLATTI , MARCO BLANGETTI , GIULIA D’ARRIGO, FRANCESCA SPYRAKIS, PAOLA CAPPELLO, CAMILLA ALBANO, SERGIO FERNANDO CASTILLO PACHECO, LINDA TRIFIRO’ , PAOLO RAVANINI , SANTO LANDOLFO, MARCO DE ANDREA, CRISTINA PRANDI , VALENTINA DELL’OSTE
Genetic Variability of Human Cytomegalovirus Clinical Isolates Correlates With Altered Expression of Natural Killer Cell-Activating Ligands and IFN-γ 2021 Galitska G.; Coscia A.; Forni D.; Steinbrueck L.; De Meo S.; Biolatti M.; De Andrea M.; Cagliani R.; Leone A.; Bertino E.; Schulz T.; Santoni A.; Landolfo S.; Sironi M.; Cerboni C.; Dell'Oste V.
Novel antiviral activity of PADs inhibitors against human beta-coronaviruses SARS-CoV-2 and HCoV-OC43 2021 SELINA PASQUERO, GLORIA GRIFFANTE, FRANCESCA GUGLIESI, MATTEO BIOLATTI, CAMILLA ALBANO, SERGIO FERNANDO CASTILLO PACHECO, GRETA BAJETTO, VALENTINA DELL’OSTE, SERENA DELBUE, SILVIA PARAPINI, SANTO LANDOLFO, MARCO DE ANDREA.
Herpes simplex virus type 1 induced citrullination in neuronal cells suggests new therapeutic options for the treatment of virus-associated neurodegenerative disorders 2021 SELINA PASQUERO, GLORIA GRIFFANTE, FRANCESCA GUGLIESI, MATTEO BIOLATTI, CAMILLA ALBANO, SERGIO FERNANDO CASTILLO PACHECO, GRETA BAJETTO, VALENTINA DELL’OSTE, SANTO LANDOLFO, MARCO DE ANDREA
PAD2 FOR USE IN DIAGNOSING INFECTIONS CAUSED BY VIRUSES OF THE HERPESVIRIDAE FAMILY AND INHIBITORS OR ANTAGONISTS OF PAD2 FOR USE AS ANTI-VIRAL AGENTS AGAINST VIRUSES OF THE HERPESVIRIDAE FAMILY 2020 LANDOLFO SANTO, GUGLIESI FRANCESCA, DELL'OSTE VALENTINA, PAUTASSO SARA, DE ANDREA MARCO, GRIFFANTE GLORIA, BIOLATTI MATTEO
Past and ongoing adaptation of human cytomegalovirus to its host. 2020 Alessandra Mozzi,Matteo Biolatti ,Rachele Cagliani ,Diego Forni ,Valentina Dell'Oste,Chiara Pontremoli,Chiara Vantaggiato,Uberto Pozzoli,Mario Clerici,Santo Landolfo,Manuela Sironi
Strigolactone Analogs Are Promising Antiviral Agents for the Treatment of Human Cytomegalovirus Infection 2020 CAMILLA ALBANO, MATTEO BIOLATTI, MARCO BLANGETTI, GIULIA D’ARRIGO, FRANCESCA SPYRAKIS, PAOLA CAPPELLO, PAOLO RAVANINI, SELINA PASQUERO, FRANCESCA GUGLIESI, SERGIO F. CASTILLO PACHECO, SANTO LANDOLFO, MARCO DE ANDREA, CRISTINA PRANDI, VALENTINA DELL’OSTE
Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding 2020 A Iannucci, V Caneparo, S Raviola, I Debernardi, D Colangelo, R Miggiano, G Griffante, S Landolfo, M Gariglio, De Andrea Marco
Strigolactone Analogs Are Promising Antiviral Agents for the Treatment of Human Cytomegalovirus Infection. 2020 Matteo Biolatti, Marco Blangetti, Giulia D’Arrigo, Francesca Spyrakis, Paola Cappello, Camilla Albano, Paolo Ravanini, Santo Landolfo, Marco De Andrea, Cristina Prandi, Valentina Dell’Oste
SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity 2020 Simone De Meo , Valentina Dell'Oste, Rosa Molfetta , Valentina Tassinari , Lavinia Vittoria Lotti , Simone Vespa , Benedetta Pignoloni , Daniela Angela Covino , Laura Fantuzzi , Roberta Bona , Alessandra Zingoni , Ilaria Nardone , Matteo Biolatti , Alessandra Coscia , Rossella Paolini , Monsef Benkirane , Fredrik Edfors , Tatyana Sandalova , Adnane Achour , John Hiscott , Santo Landolfo , Angela Santoni , Cristina Cerboni
Metabolic games: IFI16-driven regulation of cellular metabolism upon HCMV infection 2019 MATTEO BIOLATTI, GLORIA GRIFFANTE, VALENTINA DELL’OSTE, FRANCESCA GUGLIESI, GANNA GALITSKA, SELINA PASQUERO, CAMILLA ALBANO, MARTA VALLINO, PAOLO ETTORE PORPORATO, MARTIN R. JAKOBSEN, MARCO DE ANDREA, SANTO LANDOLFO
PYHIN genes as potential biomarkers for prognosis of human papillomavirus-positive or -negative head and neck squamous cell carcinomas. 2019 Giuseppe Riva, · Giancarlo Pecorari, · Matteo Biolatti, · Sara Pautasso, · Irene Lo Cigno, · Massimiliano Garzaro, · Valentina Dell’Oste, · Santo Landolfo
Strigolactones as antiviral drugs to inhibit Herpesvirus replication 2019 SELINA PASQUERO, GLORIA GRIFFANTE, FRANCESCA GUGLIESI, VALENTINA DELL’OSTE, MATTEO BIOLATTI, GANNA GALITSKA, MARCO BLANGETTI, CRISTINA PRANDI, PAOLA CAPPELLO, FRANCESCA SPYRAKIS, GIULIA D’ARRIGO, MARCO DE ANDREA, SANTO LANDOLFO
A leopard can change its spots: how HCMV genetic variability impacts viral fitness and NK ligands immunomodulation 2019 VALENTINA DELL’OSTE, GANNA GALITSKA, MATTEO BIOLATTI, SIMONE DE MEO, AGATA LEONE, ENRICO BERTINO, RACHELE CAGLIANI, DIEGO FORNI, MANUELA SIRONI, LARS STEINBRUECK, THOMAS SCHULZ, MARCO DE ANDREA, ANGELA SANTONI, CRISTINA CERBONI, SANTO LANDOLFO
PYHIN Proteins and HPV: Role in the Pathogenesis of Head and Neck Squamous Cell Carcinoma 2019 Riva Giuseppe, Biolatti Matteo, Pecorari Giancarlo, Dell'Oste Valentina, Landolfo Santo
STRIGOLACTONES FOR USE IN PREVENTING AND/OR TREATING INFECTIONS CAUSED BY VIRUSES OF THE HERPESVIRIDAE FAMILY 2019 LANDOLFO SANTO, DE ANDREA MARCO, DELL'OSTE VALENTINA, BIOLATTI MATTEO, PRANDI CRISTINA, BLANGETTI MARCO, ARTUSO EMMA, LOMBARDI CHIARA
Peptidyl Arginine Deiminases: a Novel Antiviral Target against Human Cytomegalovirus 2019 Gloria Griffante , Francesca Gugliesi , Selina Pasquero , Valentina Dell’Oste , Matteo Biolatti , Camilla Albano , Sergio F. Castillo Pacheco , Ari Salinger , Paul R. Thompson , Eranthie Weerapana , Robert J. Lebbink , Jasper A. Soppe , Marco De Andrea , Santo Landolfo
Interferon gamma inducible protein 16 (IFI16) expression is reduced in mantle cell lymphoma 2019 Pier Paolo Piccaluga, Mohsen Navari, Axel Visani, Flavia Rigotti, Claudio Agostinelli, Simona Righi, Erica Diani, Marco Ligozzi, Maria Carelli, Cristina Ponti, Isabella Bon,iDonato Zipeto, Santo Landolfo, Davide Gibellinig
HPV E7 Oncoprotein Subverts Host Innate Immunity Via SUV39H1-Mediated Epigenetic Silencing of Immune Sensor Genes 2019 Lo Cigno, Irene; Calati, Federica; Borgogna, Cinzia; Zevini, Alessandra; Albertini, Silvia; Martuscelli, Licia; De Andrea, Marco; Hiscott, John; Landolfo, Santo; Gariglio, Marisa
Metabolic Games: IFI16-Driven Regulation of Cellular Metabolism upon HCMV Infection 2019 Matteo Biolatti, Gloria Griffante, Valentina Dell’Oste, Francesca Gugliesi, Ganna Galitska, Selina Pasquero, Camilla Albano, Sergio Fernando Castillo Pacheco, Paolo Ettore Porporato, Marta Vallino, Martin Roelsgaard Jakobsen, Marco De Andrea, Santo Landolfo
Catch me if you can: the arms race between human cytomegalovirus and the innate immune system [Ganna Galitska*, Matteo Biolatti*, equal contribution) 2019 Ganna Galitska‡, Matteo Biolatti‡, Gloria Griffante, Francesca Gugliesi, Selina Pasquero, Valentina Dell'Oste, Santo Landolfo
Citrullination during Human Cytomegalovirus infection: implications for autoimmune diseases 2018 SELINA PASQUERO, GLORIA GRIFFANTE, FRANCESCA GUGLIESI, SARA PAUTASSO, VALENTINA DELL’OSTE, MATTEO BIOLATTI, GANNA GALITSKA, MARCO DE ANDREA, SANTO LANDOLFO
HPV18 Persistence Impairs Basal and DNA Ligand-Mediated IFN-β and IFN-λ1 Production through Transcriptional Repression of Multiple Downstream Effectors of Pattern Recognition Receptor Signaling. 2018 Silvia Albertini, Irene Lo Cigno, Federica Calati, Marco De Andrea, Cinzia Borgogna, Valentina Dell’Oste, Santo Landolfo, Marisa Gariglio
Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity 2018 Pautasso S, Galitska G, Dell'Oste V, Biolatti M, Cagliani R, Forni D, De Andrea M, Gariglio M, Sironi M, Landolfo S.
Biological relevance of Cytomegalovirus genetic variability in congenitally and postnatally infected children. [*Dell'Oste V, *Landolfo S, co-corresponding authors] 2018 Ganna Galitska, Matteo Biolatti, Marco De Andrea, Agata Leone, Alessandra Coscia, Luigi Bertolotti, Ugo Ala, Enrico Bertino, Valentina Dell’Oste, Santo Landolfo
The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1β by Human Cytomegalovirus through Inhibition of NF-kB Activity 2018 Matteo Biolatti, Valentina Dell’Oste, Sara Scutera, Francesca Gugliesi, Gloria Griffante , Marco De Andrea , Tiziana Musso, Santo Landolfo
Modulation of the innate immune response by human cytomegalovirus. [*Dell'Oste V., Landolfo S. co-corresponding authors] 2018 Biolatti Matteo, Gugliesi Francesca, Dell'Oste Valentina, Landolfo Santo,
The human cytomegalovirus tegument protein pp65 (pUL83): a key player in innate immune evasion 2018 Biolatti, Matteo; Dell'Oste, Valentina; De Andrea, Marco; Landolfo, Santo
Evasion strategy of Human Cytomegalovirus from the antiviral activities of APOBEC3G 2018 Matteo Biolatti, Sara Pautasso, Ganna Galitska, Valentina Dell Oste, Rachele Cagliani, Diego Forni, Marco De Andrea, Marisa Gariglio, Manuela Sironi, Santo Landolfo
Evasion Strategy of Human Cytomegalovirus to Escape Interferon-β-Induced APOBEC3G Editing Activity 2018 Sara Pautasso, Ganna Galitska, Valentina Dell’Oste, Matteo Biolatti, Rachele Cagliani, Diego Forni, Marco De Andrea, Marisa Gariglio, Manuela Sironi, Santo Landolfo
A Leopard Can Change Its Spots: How HCMV Genetic Variability Impacts Viral Fitness and NK Ligands Immunomodulation 2018 Ganna Galitska, Valentina Dell’Oste, Matteo Biolatti, Simone De Meo, Agata Leone, Enrico Bertino, Rachele Cagliani, Diego Forni, Manuela Sironi, Marco De Andrea, Angela Santoni, Cristina Cerboni, Santo Landolfo
The absent in melanoma 2-like receptor IFN-inducible protein 16 as an inflammasome regulator in systemic lupus erythematosus: The dark side of sensing microbes 2018 Caneparo, Valeria; Landolfo, Santo; Gariglio, Marisa; De Andrea, Marco
The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1β by Human Cytomegalovirus through Inhibition of NF-kB Activity. [*Biolatti M, *Dell'Oste V, co-first authors] 2018 Matteo Biolatti , Valentina Dell’Oste, Sara Scutera , Francesca Gugliesi , Gloria Griffante , Marco De Andrea, Tiziana Musso , Santo Landolfo
P600 Clinical utility of anti-IFI16 seroreactivity in the response to anti-TNF therapy in IBD 2018 Caneparo, V; Verstockt, B; Vermeire, S; Landolfo, S; Gariglio, M; De Andrea, M
The Human Cytomegalovirus Tegument Protein pp65 (pUL83) Dampens Type I Interferon Production by Inactivating the DNA Sensor cGAS without Affecting STING [*Biolatti M, Dell'Oste V* co-first authors] 2018 Biolatti M, Dell'Oste V, Pautasso S, Gugliesi F, von Einem J, Krapp C, Jakobsen MR, Borgogna C, Gariglio M, De Andrea M, Landolfo S
CHARACTERIZATION OF POST-TRANSLATIONAL MODIFICATIONS DURING HUMAN CYTOMEGALOVIRUS INFECTION: IMPLICATIONS FOR NOVEL ANTIVIRALS 2018 Griffante Gloria, Gugliesi Francesca, Selina Pasquero ,Pautasso Sara, Valentina Dell’Oste, Matteo Biolatti, Ari Salinger, Paul R. Thompson, Marco De Andrea, Santo Landolfo
Prevalence of HPV infection in racial-ethnic subgroups of head and neck cancer patients 2017 Ragin, Camille ; C. Liu, Jeffrey; Jones, Gieira; Shoyele, Olubunmi; Sowunmi, Bukola; Kennett, Rachel; Gibbs, Denise; Blackman, Elizabeth; Esan, Michael; Brandwein, Margaret S.; Devarajan, Karthik; Bussu, Francesco ; Chernock, Rebecc; Chien, Chih-Yen; Cohen, Marc A.; El-Mofty, Samir; Suzuki, Mikio; D’Souza, Gypsyamber; Funchain, Pauline; Eng, Charis; Gollin, Susanne M.; Hong, Angela;Jung, Yuh-S; Krüger, Maximilian ;Lewis Jr, James ; Morbini, Patrizia ; Landolfo, Santo ; Rittà, Massimo ; Straetmans, Jos ; Szarka, Krisztina ; Tachezy, Ruth ; Worden, Francis P ; Nelson, Deborah; Gathere, Samuel ; Taioli, Emanuela
Genotypic analysis of HCMV polymorphism in congenital infections to predict the impact of HCMV disease severity in newborns/infants 2017 Galitska, Ganna; Dell'Oste, Valentina; Biolatti, Matteo; Marco, De Andrea; Leone, Agata; Enrico, Bertino; Landolfo, Santo
P178 Validation of the clinical utility of IFI16-based markers in IBD 2017 V. Caneparo, L. Pastorelli, E. Vanni, D. Roggenbuck, R. Boldorini, M. Astegiano, M. Vecchi, S. Landolfo, M. Gariglio, M. De Andrea
Relevance of Interferon-Inducible Protein-16 Rather than Anti-Interferon-Inducible Protein-16 Autoantibodies as a Clinical and Pathogenic Biomarker in Primary Sjögren's Syndrome: Comment on the Article by Baer et al. 2017 Alunno, A; Bartoloni, E; Bistoni, O; Gerli, R; Caneparo, V; Carubbi, F; Landolfo, S
IFI16 reduced expression is correlated with unfavorable outcome in chronic lymphocytic leukemia 2017 Piccaluga PP, Agostinelli C, Righi S, Ciccone M, Re MC, Musumeci G, Diani E, Signoretto C, Bon I, Piccin O, Cuneo A, Tripodo C, Ponti C, Zipeto D, Landolfo Santo, Gibellini D
THE ROLE OF ANTI-IFI16 ANTIBODIES IN THE MANAGEMENT OF INFLAMMATORY BOWEL DISEASES (IBD) 2017 Astegiano, M.; Vanni, E.; Finocchiaro, F.; Vernero, M.; Ribaldone, D.; Reggiani, S.; Caviglia, G.; De Andrea, M.; Caneparo, V.; Landolfo, S.; Gariglio, M.; Smedile, A.; Pellicano, R.
The human Cytomegalovirus tegument protein pp65 (pUL83) dampens interferon-type I production by inactivating the DNA sensor cGAS 2017 Dell’Oste, Valentina; Biolatti, Matteo; Pautasso, Sara; Gugliesi, Francesca; Andrea, Marco De; Einem, Jens Von; Gariglio, Marisa; Landolfo, Santo
The DNA Cytosine Deaminase APOBEC3G is upregulated during Human Cytomegalovirus infection 2017 Pautasso, Sara; Galitska, Ganna; Dell’Oste, Valentina; Biolatti, Matteo; Gugliesi, Francesca; Griffante, Gloria; Gariglio, Marisa; De Andrea, Marco; Landolfo, Santo
Regulatory Interaction between the Cellular Restriction Factor IFI16 and Viral pp65 (pUL83) Modulates Viral Gene Expression and IFI16 Protein Stability [*Biolatti M, *Dell'Oste V, co-first authors] 2016 Biolatti, Matteo; Dell'Oste, Valentina; Pautasso, Sara; von Einem, Jens; Marschall, Manfred; Plachter, Bodo; Gariglio, Marisa; De Andrea, Marco; Landolfo, Santo
Circulating Interferon-Inducible Protein IFI16 Correlates With Clinical and Serological Features in Rheumatoid Arthritis. 2016 Alunno, Alessia ; Caneparo, Valeria; Bistoni, Onelia; Caterbi, Sara; Terenzi, Riccardo; Gariglio, Marisa; Bartoloni, Elena; Manzo, Antonio; Landolfo, Santo; Gerli, Roberto
Regulatory Interaction between the Cellular Restriction Factor IFI16 and Viral pp65 (pUL83) Modulates Viral Gene Expression and IFI16 Protein Stability 2016 Biolatti, Matteo; Dell’Oste, Valentina; Pautasso, Sara; Einem, Jens von; Marschall, Manfred; Plachter, Bodo; Gariglio, Marisa; De Andrea, Marco; Landolfo, Santo
Regulatory interaction between the cellular restriction factor IFI16 and viral pp65 (pUL83) modulates viral gene expression and IFI16 protein stability 2016 Dell’Oste, Valentina; Biolatti, Matteo; Pautasso, Sara; Einem, Jens von; Marschall, Manfred; Plachte, Bodo; Gariglio, Marisa; De Andrea Marco; Landolfo, Santo
Interferon α/β 2016 Landolfo, Santo; De Andrea, Marco
Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the transcriptional regulation of MICA and PVR/CD155 expression. 2016 Pignoloni, Benedetta; Fionda, Cinzia; Dell’Oste, Valentina; Luganini, Anna; Cippitelli, Marco; Zingoni, Alessandra; Landolfo, Santo; Gribaudo, Giorgio; Santoni, Angela; Cerboni, Cristina
The interferon-inducible DNA-sensor protein IFI16: a key player in the antiviral response 2016 Sara, Pautasso; Matteo, Biolatti; Valentina, Dell’Oste; Francesca, Gugliesi; Marisa, Gariglio; Marco, De Andrea; Santo, Landolfo
Human Cytomegalovirus pp65 inhibits Interferon type I production through its interaction with the cGAS/STING axis 2016 Pautasso, Sara; Biolatti, Matteo; Dell’Oste, Valentina; Gugliesi, Francesca; Marco De Andrea, Gariglio, Marisa; Landolfo, Santo
INNATE NUCLEAR SENSOR IFI16 TRANSLOCATES INTO THE CYTOPLASM DURING EARLY STAGE OF IN VITRO HCMV INFECTION AND IS ENTRAPPED IN THE EGRESSING VIRIONS DURING LATE STAGE 2016 Dell’Oste, Valentina; Leone, Agata; Marco De Andrea; Marschall, Manfred; Gariglio, Marisa; Bertino, Enrico; Landolfo, Santo
Intrinsic host restriction factors of human cytomegalovirus replication and mechanisms of viral escape 2016 Landolfo, Santo; De Andrea, Marco; Dell'Oste, Valentina; Gugliesi, Francesca
Distinct Anti-IFI16 and Anti-GP2 Antibodies in Inflammatory Bowel Disease and Their Variation with Infliximab Therapy 2016 Caneparo, Valeria; Pastorelli, Luca; Pisani, Laura Francesca; Bruni, Barbara; Prodam, Flavia; Boldorini, Renzo; Roggenbuck, Dirk; Vecchi, Maurizio; Landolfo, Santo; Gariglio, Marisa; De Andrea, Marco
The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human Papillomavirus Replication through Epigenetic Modifications of the Viral Promoters 2015 Irene Lo Cigno, Cinzia Borgogna, Silvia Albertini, Manuela M. Landini, Alberto Peretti, Karen E. Johnson, Bala Chandran, Santo Landolfo, Marisa Gariglio, Marco De Andrea
The IFI16 restriction factor cooperates with HCMV pUL83 to down-regulate UL54 gene expression and viral DNA synthesis 2015 Matteo Biolatti, Sara Pautasso, Valentina Dell’Oste, Marco De Andrea, Jens von Einem, Bodo Plachter, Manfred Marschall, Marisa Gariglio, Santo Landolfo
Interferon-α Production by Plasmacytoid Dendritic Cells Is Dispensable for an Effective Anti-Cytomegalovirus Response in Adaptor Protein-3-Deficient Mice. [Del Prete A.*, Luganini A.* co-first author] 2015 Del Prete A*; Luganini A*; Scutera S; Rossi S; Anselmo A; Greco D; Landolfo S; Badolato R;Gribaudo G; Sozzani S; Musso T (* co-first author)
The nuclear Interferon-inducible IFI16 protein and the innate sensing to HPV18 replication 2015 Marco De Andrea, Irene Lo Cigno, Silvia Albertini, Cinzia Borgogna, Alberto Peretti, Karen Johnson, Bala Chandran, Santo Landolfo, Marisa Gariglio
Interferon gamma-inducible protein 16 in primary Sjögren's syndrome: a novel player in disease pathogenesis? 2015 Alunno, Alessia; Caneparo, Valeria; Carubbi, Francesco; Bistoni, Onelia; Caterbi, Sara; Bartoloni, Elena; Giacomelli, Roberto; Gariglio, Marisa; Landolfo, Santo; Gerli, Roberto
IFI16 expression is related to selected transcription factors during B-cell differentiation 2015 Piccaluga, Pier Paolo; Agostinelli, Claudio; Fuligni, Fabio; Righi, Simona; Tripodo, Claudio; Re, Maria Carla; Clò, Alberto; Miserocchi, Anna; Morini, Silvia; Gariglio, Marisa; Ferri, Gian Gaetano; Rinaldi-Ceroni, Alberto; Piccin, Ottavio; De Andrea, Marco; Pileri, Stefano A.; Landolfo, Santo; Gibellini, Davide
The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human Papillomavirus Replication through Epigenetic Modifications of the Viral Promoters. M. DE ANDREA CO-FIRST AUTHOR 2015 I. Lo Cigno; M. De Andrea; C. Borgogna; S. Albertini; M. Landini; A. Peretti; K. Johnson; B. Chandran; S. Landolfo; M. Gariglio
The interferon-inducible DNa-sensor protein IFI16: a key player in the antiviral response. 2015 Dell'Oste V; Gatti D; Giorgio AG; Gariglio M; Landolfo S; De Andrea M
Interferon gamma-inducible protein 16 (IFI16) and anti-IFI16 antibodies in primary Sjögren's syndrome: findings in serum and minor salivary glands. 2015 Alunno, Alessia; Caneparo, Valeria; Carubbi, A; Bistoni, O; Caterbi; Gariglio, M; Bartoloni, E; Landolfo, S; Gerli, R;
The IFI16 restriction factor cooperates with HCMV pUL83 to down-regulate UL54 gene expression and viral DNA synthesis. 2015 Sara Pautasso, Matteo Biolatti, Valentina Dell’Oste, Marco De Andrea, Jens von Einem, Bodo Plachter, Manfred Marschall, Marisa Gariglio, Santo Landolfo
Restriction of HPV18 Replication in the Nucleus by IFI16: what about Innate Sensing? 2015 M. De Andrea, S. Albertini, F. Calati, I. Lo Cigno, C. Borgogna, K. Johnson, B. Chandran, S. Landolfo, M. Gariglio
Restriction of HPV18 replication in the nucleus by IFI16: what about innate sensing? 2015 S. Albertini, I. Lo Cigno, M. De Andrea, C. Borgogna, A. Peretti, G. Gherardi , K.E. Johnson, B. Chandran, S. Landolfo, M. Gariglio
The Extracellular IFI16 Protein Propagates Inflammation in Endothelial Cells Via p38 MAPK and NF-κB p65 Activation 2015 Bawadekar M; De Andrea M; Lo Cigno I; Baldanzi G; Caneparo V; Graziani A; Landolfo S; Gariglio M.
The IFI16 restriction factor cooperates with HCMV pUL83 to down-regulate UL54 gene expression and viral DNA synthesis. 2015 Dell’Oste, Valentina; Biolatti, Matteo; Pautasso, Sara; Andrea, Marco De; Einem, Jens von; Plachter, Bodo; Marschall, Manfred; Gariglio, Marisa; Landolfo, Santo .
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