Sfoglia per Autore
Do P2Y12 receptor antagonism and NLRP3 inhibition exert additive cardioprotective effects against ischemia/reperfusion injury?
2019-01-01 Fausto Chiazza, Saveria Femminò, Debora Collotta, Elisa Zicola, Manuela Aragno, Massimo Bertinaria, Pasquale Pagliaro, Claudia Penna, Massimo Collino
Targeting NLRP3 inflammasome: development of new covalent and non-covalent inhibitors of ATPase activity
2019-01-01 Elisabetta Marini, Simone Gastaldi, Marta Giorgis, Marco Marino, Valentina Boscaro, Margherita Gallicchio, Massimo Bertinaria
Pharmacological characterization of new NLRP3 inflammasome inhibitors.
2019-01-01 Valentina Boscaro, Simone Gastaldi, Marco Marino, Marta Giorgis, Elisabetta Marini, Massimo Bertinaria, Margherita Gallicchio
NEW NON-COVALENT INHIBITORS OF NLRP3 INFLAMMASOME ATPASE ACTIVITY
2019-01-01 Gastaldi, S; Marino, M.; Giorgis, M.; Marini, E.; Boscaro, V.; Gallicchio, M.; Bertinaria, M.
In silico study of NLRP3: towards selective inhibition with small molecules
2019-01-01 Alejandro Gómez García, Simone Gastaldi, Giulia Fumero, Massimo Bertinaria, José Luis Medina Franco
Inhibition of NLRP3 ATPase activity: a new strategy to fight chronic inflammatory diseases
2019-01-01 Simone Gastaldi, Federica Blua, Marta Giorgis, Elisabetta Marini, Massimo Bertinaria
Development of covalent NLRP3 inflammasome inhibitors: chemistry and biological activity
2019-01-01 Bertinaria Massimo, Gastaldi Simone, Marini Elisabetta, Giorgis Marta
New tools for the development of direct NLRP3 inflammasome inhibitors
2018-01-01 Elisabetta Marini, Marta Giorgis, Massimo Bertinaria
A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation
2018-01-01 Carolina Pellegrini, Matteo Fornai, Rocchina Colucci, Laura Benvenuti, Vanessa D’Antongiovanni, Gianfranco Natale, Federica Fulceri, Marta Giorgis, Elisabetta Marini, Simone Gastaldi, Massimo Bertinaria, Corrado Blandizzi, Luca Antonioli
Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells from Type2 Diabetes Patients: Rescue by alpha Ketoglutarate and TET-TDG Functional Reactivation
2018-01-01 Spallotta, Francesco; Cencioni, Chiara; Atlante, Sandra; Garella, Davide; Cocco, Mattia; Mori, Mattia; Mastrocola, Raffaella; Kuenne, Carsten; Guenther, Stefan; Nanni, Simona; Azzimato, Valerio; Zukunft, Sven; Kornberger, Angela; Sã¼rã¼n, Duran; Schnã¼tgen, Frank; Von Melchner, Harald; Di Stilo, Antonella; Aragno, Manuela; Braspenning, Maarten; Van Criekinge, Wim; De Blasio, Miles J.; Ritchie, Rebecca H.; Zaccagnini, Germana; Martelli, Fabio; Farsetti, Antonella; Fleming, Ingrid; Braun, Thomas; Beiras-Fernandez, Andres; Botta, Bruno; Collino, Massimo; Bertinaria, Massimo; Zeiher, Andreas M.; Gaetano, Carlo
α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis
2018-01-01 Atlante, Sandra; Visintin, Alessia; Marini, Elisabetta; Savoia, Matteo; Dianzani, Chiara; Giorgis, Marta; Sürün, Duran; Maione, Federica; Schnütgen, Frank; Farsetti, Antonella; Zeiher, Andreas M; Bertinaria, Massimo; Giraudo, Enrico; Spallotta, Francesco; Cencioni, Chiara; Gaetano, Carlo
Nonsteroidal anti-inflammatory drugs: Exploiting bivalent COXIB/TP antagonists for the control of cardiovascular risk
2017-01-01 Carnevali, Silvia; Buccellati, Carola; Bolego, Chiara; Bertinaria, Massimo; Rovati, G. Enrico*; Sala, Angelo
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
2017-01-01 Cocco, Mattia; Pellegrini, Carolina; Martínez-Banaclocha, Helios; Giorgis, Marta; Marini, Elisabetta; Costale, Annalisa; Miglio, Gianluca; Fornai, Matteo; Antonioli, Luca; López-Castejón, Gloria; Tapia-Abellán, Ana; Angosto, Diego; Hafner-Bratkovič, Iva; Regazzoni, Luca; Blandizzi, Corrado; Pelegrín, Pablo; Bertinaria, Massimo
Cardiac Epi-Metabolic Signature Revealed by Integrated Omics Approach in Diabetic Patients: Rescue by Active DNA Demethylation via TET-TDG Complex Reactivation
2016-01-01 Spallotta, F; Cencioni, C; Atlante, S; Garella, D; Cocco, M; Mori, M; Mastrocola, R; Kuenne, C; Guenther, S; Nanni, S; Azzimato, V; Zukunft, S; Kornberger, A; Di Stilo, A; Aragno, M; Martelli, F; Farsetti, A; Fleming, I; Braun, T; Beiras-Fernandez, A; Botta, B; Collino, M; Bertinaria, M; Zeiher, Am; Gaetano, C.
Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors
2016-01-01 Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández de Gortari, Eli; Medina Franco, José L.; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo
In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition
2016-01-01 Malvina Hoxha; Buccellati, Carola; Capra, Valérie; Garella, Davide; Cena, Clara; Rolando, Barbara; Fruttero, Roberta; Carnevali, Silvia; Sala, Angelo; Rovati, G.Enrico; Bertinaria, Massimo.
Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia/reperfusion injury by activation of RISK and mitochondrial pathways
2016-01-01 Mastrocola, Raffaella; Penna, Claudia; Tullio, Francesca; Femminò, Saveria; Nigro, Debora; Chiazza, Fausto; Serpe, Loredana; Collotta, Debora; Alloatti, Giuseppe; Cocco, Mattia; Bertinaria, Massimo; Pagliaro, Pasquale; Aragno, Manuela; Collino, Massimo
Targeting of NLRP3 Inflammasome With a Novel Selective Inhibitor as a Suitable Strategy for the Pharmacological Treatment of Bowel Inflammation
2016-01-01 Pellegrini C.; Fornai M.; Colucci R.; Lopez-Castejon G.; Cocco M.; Garella D.; Bertinaria M.; Blandizzi C.; Antonioli L
Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors
2016-01-01 Cocco, Mattia; Miglio, Gianluca; Giorgis, Marta; Garella, Davide; Marini, Elisabetta; Costale, Annalisa; Regazzoni, Luca; Vistoli, Giulio; Orioli, Marica; Massulaha-Ahmed, Raïhane; Détraz-Durieux, Isabelle; Groslambert, Marine; Py, Bénédicte F.; Bertinaria, Massimo
NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria
2015-01-01 Bertinaria, Massimo; Orjuela-Sanchez, Pamela; Marini, Elisabetta; Guglielmo, Stefano; Hofer, Anthony; Martins, Yuri C.; Zanini, Graziela M.; Frangos, John A.; Gasco, Alberto; Fruttero, Roberta; Carvalho, Leonardo J. M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Do P2Y12 receptor antagonism and NLRP3 inhibition exert additive cardioprotective effects against ischemia/reperfusion injury? | 2019 | Fausto Chiazza, Saveria Femminò, Debora Collotta, Elisa Zicola, Manuela Aragno, Massimo Bertinaria, Pasquale Pagliaro, Claudia Penna, Massimo Collino | |
| Targeting NLRP3 inflammasome: development of new covalent and non-covalent inhibitors of ATPase activity | 2019 | Elisabetta Marini, Simone Gastaldi, Marta Giorgis, Marco Marino, Valentina Boscaro, Margherita Gallicchio, Massimo Bertinaria | |
| Pharmacological characterization of new NLRP3 inflammasome inhibitors. | 2019 | Valentina Boscaro, Simone Gastaldi, Marco Marino, Marta Giorgis, Elisabetta Marini, Massimo Bertinaria, Margherita Gallicchio | |
| NEW NON-COVALENT INHIBITORS OF NLRP3 INFLAMMASOME ATPASE ACTIVITY | 2019 | Gastaldi, S; Marino, M.; Giorgis, M.; Marini, E.; Boscaro, V.; Gallicchio, M.; Bertinaria, M. | |
| In silico study of NLRP3: towards selective inhibition with small molecules | 2019 | Alejandro Gómez García, Simone Gastaldi, Giulia Fumero, Massimo Bertinaria, José Luis Medina Franco | |
| Inhibition of NLRP3 ATPase activity: a new strategy to fight chronic inflammatory diseases | 2019 | Simone Gastaldi, Federica Blua, Marta Giorgis, Elisabetta Marini, Massimo Bertinaria | |
| Development of covalent NLRP3 inflammasome inhibitors: chemistry and biological activity | 2019 | Bertinaria Massimo, Gastaldi Simone, Marini Elisabetta, Giorgis Marta | |
| New tools for the development of direct NLRP3 inflammasome inhibitors | 2018 | Elisabetta Marini, Marta Giorgis, Massimo Bertinaria | |
| A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation | 2018 | Carolina Pellegrini, Matteo Fornai, Rocchina Colucci, Laura Benvenuti, Vanessa D’Antongiovanni, Gianfranco Natale, Federica Fulceri, Marta Giorgis, Elisabetta Marini, Simone Gastaldi, Massimo Bertinaria, Corrado Blandizzi, Luca Antonioli | |
| Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells from Type2 Diabetes Patients: Rescue by alpha Ketoglutarate and TET-TDG Functional Reactivation | 2018 | Spallotta, Francesco; Cencioni, Chiara; Atlante, Sandra; Garella, Davide; Cocco, Mattia; Mori, Mattia; Mastrocola, Raffaella; Kuenne, Carsten; Guenther, Stefan; Nanni, Simona; Azzimato, Valerio; Zukunft, Sven; Kornberger, Angela; Sã¼rã¼n, Duran; Schnã¼tgen, Frank; Von Melchner, Harald; Di Stilo, Antonella; Aragno, Manuela; Braspenning, Maarten; Van Criekinge, Wim; De Blasio, Miles J.; Ritchie, Rebecca H.; Zaccagnini, Germana; Martelli, Fabio; Farsetti, Antonella; Fleming, Ingrid; Braun, Thomas; Beiras-Fernandez, Andres; Botta, Bruno; Collino, Massimo; Bertinaria, Massimo; Zeiher, Andreas M.; Gaetano, Carlo | |
| α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis | 2018 | Atlante, Sandra; Visintin, Alessia; Marini, Elisabetta; Savoia, Matteo; Dianzani, Chiara; Giorgis, Marta; Sürün, Duran; Maione, Federica; Schnütgen, Frank; Farsetti, Antonella; Zeiher, Andreas M; Bertinaria, Massimo; Giraudo, Enrico; Spallotta, Francesco; Cencioni, Chiara; Gaetano, Carlo | |
| Nonsteroidal anti-inflammatory drugs: Exploiting bivalent COXIB/TP antagonists for the control of cardiovascular risk | 2017 | Carnevali, Silvia; Buccellati, Carola; Bolego, Chiara; Bertinaria, Massimo; Rovati, G. Enrico*; Sala, Angelo | |
| Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease | 2017 | Cocco, Mattia; Pellegrini, Carolina; Martínez-Banaclocha, Helios; Giorgis, Marta; Marini, Elisabetta; Costale, Annalisa; Miglio, Gianluca; Fornai, Matteo; Antonioli, Luca; López-Castejón, Gloria; Tapia-Abellán, Ana; Angosto, Diego; Hafner-Bratkovič, Iva; Regazzoni, Luca; Blandizzi, Corrado; Pelegrín, Pablo; Bertinaria, Massimo | |
| Cardiac Epi-Metabolic Signature Revealed by Integrated Omics Approach in Diabetic Patients: Rescue by Active DNA Demethylation via TET-TDG Complex Reactivation | 2016 | Spallotta, F; Cencioni, C; Atlante, S; Garella, D; Cocco, M; Mori, M; Mastrocola, R; Kuenne, C; Guenther, S; Nanni, S; Azzimato, V; Zukunft, S; Kornberger, A; Di Stilo, A; Aragno, M; Martelli, F; Farsetti, A; Fleming, I; Braun, T; Beiras-Fernandez, A; Botta, B; Collino, M; Bertinaria, M; Zeiher, Am; Gaetano, C. | |
| Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors | 2016 | Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández de Gortari, Eli; Medina Franco, José L.; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo | |
| In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition | 2016 | Malvina Hoxha; Buccellati, Carola; Capra, Valérie; Garella, Davide; Cena, Clara; Rolando, Barbara; Fruttero, Roberta; Carnevali, Silvia; Sala, Angelo; Rovati, G.Enrico; Bertinaria, Massimo. | |
| Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia/reperfusion injury by activation of RISK and mitochondrial pathways | 2016 | Mastrocola, Raffaella; Penna, Claudia; Tullio, Francesca; Femminò, Saveria; Nigro, Debora; Chiazza, Fausto; Serpe, Loredana; Collotta, Debora; Alloatti, Giuseppe; Cocco, Mattia; Bertinaria, Massimo; Pagliaro, Pasquale; Aragno, Manuela; Collino, Massimo | |
| Targeting of NLRP3 Inflammasome With a Novel Selective Inhibitor as a Suitable Strategy for the Pharmacological Treatment of Bowel Inflammation | 2016 | Pellegrini C.; Fornai M.; Colucci R.; Lopez-Castejon G.; Cocco M.; Garella D.; Bertinaria M.; Blandizzi C.; Antonioli L | |
| Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors | 2016 | Cocco, Mattia; Miglio, Gianluca; Giorgis, Marta; Garella, Davide; Marini, Elisabetta; Costale, Annalisa; Regazzoni, Luca; Vistoli, Giulio; Orioli, Marica; Massulaha-Ahmed, Raïhane; Détraz-Durieux, Isabelle; Groslambert, Marine; Py, Bénédicte F.; Bertinaria, Massimo | |
| NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria | 2015 | Bertinaria, Massimo; Orjuela-Sanchez, Pamela; Marini, Elisabetta; Guglielmo, Stefano; Hofer, Anthony; Martins, Yuri C.; Zanini, Graziela M.; Frangos, John A.; Gasco, Alberto; Fruttero, Roberta; Carvalho, Leonardo J. M. |
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