Sfoglia per Autore
Alternative BCR/ABL splice variants in Philadelphia chromosome-positive leukemias result in novel tumor-specific fusion proteins that may represent potential targets for immunotherapy approaches
2007-01-01 VOLPE G; CIGNETTI A; PANUZZO C; KUKA M; VITAGGIO K; BRANCACCIO M; PERRONE G; RINALDI M; PRATO G; FAVA M; GEUNA M; PAUTASSO M; CASNICI C; SIGNORI E; TONON G; TARONE G; MARELLI O; FAZIO VM; SAGLIO G
The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment
2008-01-01 Rolny C; Capparuccia L; Casazza A; Mazzone M; Vallario A; Cignetti A; Medico E; Carmeliet P; Comoglio PM; Tamagnone L.
Clonal CD8+ TCR-Vbeta expanded populations with effector memory phenotype in Churg Strauss syndrome
2008-01-01 Giuseppe Guida; Antonella Vallario; Stefania Stella; Monica Boita; Paola Circosta; Sara Mariani; Giuseppina Prato; Enrico Heffler; Roberta Bergia; Antonino Sottile; Giovanni Rolla; Alessandro Cignetti
Molecular and Functional Analysis of Peripheral Lymphocytes in Churg Strauss Syndrome Reveals Several Monoclonal Expansions of CD8+Cells with a Th1/Proinflammatory Profile
2012-01-01 Boita M; Circosta P; Guida G; Elia AR; Heffler E; Geuna M; Tarella C; Rolla G; Cignetti A
Current use and potential role of procalcitonin in the diagnostic work up and follow up of febrile neutropenia in hematological patients
2017-01-01 Bruno, Benedetto; Busca, Alessandro; Vallero, Stefano; Raviolo, Stefania; Mordini, Nicola; Nassi, Luca; Cignetti, Alessandro; Audisio, Ernesta; Festuccia, Moreno; Corsetti, Alessandra; Depaoli, Lorella; Faraci, Maura; Micalizzi, Concetta; Corcione, Silvia; Berger, Massimo; Saglio, Francesco; Caropreso, Paola; Mengozzi, Giulio; Squadrone, Vincenzo; De Rosa, Francesco Giuseppe; Giaccone, Luisa
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase inhibitors
2018-01-01 Sainas S., Pippione A. C., Bonanni D., Giorgis Marta, Lupino E. , Circosta P. , Gaidano V. , Cignetti A. , Piccinini M. , Saglio G. , Al-Karadaghi S. , Boschi D., Lolli M.L.
Development of Potent Human Dihydroorotate Dehydrogenase Inhibitors Able to Induces Myeloid Differentiation
2018-01-01 Stefano Sainas, Agnese C. Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco L. Lolli
New human dihydroorotate dehydrogenase inhibitors able to restore myeloid differentiation in AML
2018-01-01 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
PROCEEDINGS OF THE MERCK & ELSEVIER YOUNG CHEMISTSSYMPOSIUM
2018-01-01 Stefano Sainas, Agnese C. Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco L. Lolli
Targeting myeloid differentiation using potent human dihydroorotate dehydrogenase (hDHODH) inhibitors
2018-01-01 Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Giraudo Enrico, Goyal Parveen, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Friemann Rosmarie, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase (hDHODH) inhibitors
2018-01-01 Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Giraudo Enrico, Goyal Parveen, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Friemann Rosmarie, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio
Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms
2018-01-01 Circosta, Paola; Elia, Angela Rita; Landra, Indira; Machiorlatti, Rodolfo; Todaro, Maria; Aliberti, Sabrina; Brusa, Davide; Deaglio, Silvia; Chiaretti, Sabina; Bruna, Riccardo; Gottardi, Daniela; Massaia, Massimo; Giacomo, Filomena Di; Guarini, Anna Rita; Foà, Robin; Kyriakides, Peter W.; Bareja, Rohan; Elemento, Olivier; Chichili, Gurunadh R.; Monteleone, Emanuele; Moore, Paul A.; Johnson, Syd; Bonvini, Ezio; Cignetti, Alessandro; Inghirami, Giorgio
DHODH inhibitors and leukemia: an emergent interest for new myeloid differentiation agents
2018-01-01 Sainas, S; Pippione, AC; Boschi, D; Gaidano, V; Circosta, P; Cignetti, A; Dosio, F; Lolli, ML
A differentiating and apoptotic therapy for acute myeloid leukaemia using potent human dihydroorotate dehydrogenase inhibitors.
2019-01-01 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
Improvement of in vivo pharmacokinetic profile of M433, a potent and innovative hDHODH inhibitor.
2019-01-01 Marta Alberti, Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Donatella Boschi, Marco Lucio Lolli
Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors able to restore in vitro and in vivo myeloid differentiation
2019-01-01 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors
2019-01-01 Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio
Meds433, a New Dihydroorotate Dehydrogenase Inhibitor, Induces Apoptosis and Differentiation in Acute Myeloid Leukemia
2019-01-01 Gaidano, Valentina; Circosta, Paola; Cignetti, Alessandro; Houshmand, Mohammad; Vitale, Nicoletta; Sainas, Stefano; Pippione, Agnese; Marraudino, Marilena; Bonaldo, Brigitta; Giorgis, Marta; Boschi, Donatella; Lolli, Marco Lucio; Saglio, Giuseppe
The inhibition of human DHODH by M433 leads to differentiation and apoptosis in acute myeloid leukemia
2021-01-01 Sainas Stefano, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Gotti Stefano, Saglio Giuseppe., Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety
2021-01-01 Sainas S.; Giorgis M.; Circosta P.; Gaidano V.; Bonanni D.; Pippione A.C.; Bagnati R.; Passoni A.; Qiu Y.; Cojocaru C.F.; Canepa B.; Bona A.; Rolando B.; Mishina M.; Ramondetti C.; Buccinna B.; Piccinini M.; Houshmand M.; Cignetti A.; Giraudo E.; Al-Karadaghi S.; Boschi D.; Saglio G.; Lolli M.L.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Alternative BCR/ABL splice variants in Philadelphia chromosome-positive leukemias result in novel tumor-specific fusion proteins that may represent potential targets for immunotherapy approaches | 2007 | VOLPE G; CIGNETTI A; PANUZZO C; KUKA M; VITAGGIO K; BRANCACCIO M; PERRONE G; RINALDI M; PRATO G; FAVA M; GEUNA M; PAUTASSO M; CASNICI C; SIGNORI E; TONON G; TARONE G; MARELLI O; FAZIO VM; SAGLIO G | |
| The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment | 2008 | Rolny C; Capparuccia L; Casazza A; Mazzone M; Vallario A; Cignetti A; Medico E; Carmeliet P; Comoglio PM; Tamagnone L. | |
| Clonal CD8+ TCR-Vbeta expanded populations with effector memory phenotype in Churg Strauss syndrome | 2008 | Giuseppe Guida; Antonella Vallario; Stefania Stella; Monica Boita; Paola Circosta; Sara Mariani; Giuseppina Prato; Enrico Heffler; Roberta Bergia; Antonino Sottile; Giovanni Rolla; Alessandro Cignetti | |
| Molecular and Functional Analysis of Peripheral Lymphocytes in Churg Strauss Syndrome Reveals Several Monoclonal Expansions of CD8+Cells with a Th1/Proinflammatory Profile | 2012 | Boita M; Circosta P; Guida G; Elia AR; Heffler E; Geuna M; Tarella C; Rolla G; Cignetti A | |
| Current use and potential role of procalcitonin in the diagnostic work up and follow up of febrile neutropenia in hematological patients | 2017 | Bruno, Benedetto; Busca, Alessandro; Vallero, Stefano; Raviolo, Stefania; Mordini, Nicola; Nassi, Luca; Cignetti, Alessandro; Audisio, Ernesta; Festuccia, Moreno; Corsetti, Alessandra; Depaoli, Lorella; Faraci, Maura; Micalizzi, Concetta; Corcione, Silvia; Berger, Massimo; Saglio, Francesco; Caropreso, Paola; Mengozzi, Giulio; Squadrone, Vincenzo; De Rosa, Francesco Giuseppe; Giaccone, Luisa | |
| In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase inhibitors | 2018 | Sainas S., Pippione A. C., Bonanni D., Giorgis Marta, Lupino E. , Circosta P. , Gaidano V. , Cignetti A. , Piccinini M. , Saglio G. , Al-Karadaghi S. , Boschi D., Lolli M.L. | |
| Development of Potent Human Dihydroorotate Dehydrogenase Inhibitors Able to Induces Myeloid Differentiation | 2018 | Stefano Sainas, Agnese C. Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco L. Lolli | |
| New human dihydroorotate dehydrogenase inhibitors able to restore myeloid differentiation in AML | 2018 | Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli | |
| PROCEEDINGS OF THE MERCK & ELSEVIER YOUNG CHEMISTSSYMPOSIUM | 2018 | Stefano Sainas, Agnese C. Pippione, Davide Bonanni, Marta Giorgis, Elisa Lupino, Enrico Giraudo, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Marco Piccinini, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco L. Lolli | |
| Targeting myeloid differentiation using potent human dihydroorotate dehydrogenase (hDHODH) inhibitors | 2018 | Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Giraudo Enrico, Goyal Parveen, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Friemann Rosmarie, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio | |
| In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase (hDHODH) inhibitors | 2018 | Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Giraudo Enrico, Goyal Parveen, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Friemann Rosmarie, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio | |
| Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms | 2018 | Circosta, Paola; Elia, Angela Rita; Landra, Indira; Machiorlatti, Rodolfo; Todaro, Maria; Aliberti, Sabrina; Brusa, Davide; Deaglio, Silvia; Chiaretti, Sabina; Bruna, Riccardo; Gottardi, Daniela; Massaia, Massimo; Giacomo, Filomena Di; Guarini, Anna Rita; Foà, Robin; Kyriakides, Peter W.; Bareja, Rohan; Elemento, Olivier; Chichili, Gurunadh R.; Monteleone, Emanuele; Moore, Paul A.; Johnson, Syd; Bonvini, Ezio; Cignetti, Alessandro; Inghirami, Giorgio | |
| DHODH inhibitors and leukemia: an emergent interest for new myeloid differentiation agents | 2018 | Sainas, S; Pippione, AC; Boschi, D; Gaidano, V; Circosta, P; Cignetti, A; Dosio, F; Lolli, ML | |
| A differentiating and apoptotic therapy for acute myeloid leukaemia using potent human dihydroorotate dehydrogenase inhibitors. | 2019 | Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli | |
| Improvement of in vivo pharmacokinetic profile of M433, a potent and innovative hDHODH inhibitor. | 2019 | Marta Alberti, Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Donatella Boschi, Marco Lucio Lolli | |
| Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors able to restore in vitro and in vivo myeloid differentiation | 2019 | Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli | |
| Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors | 2019 | Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio | |
| Meds433, a New Dihydroorotate Dehydrogenase Inhibitor, Induces Apoptosis and Differentiation in Acute Myeloid Leukemia | 2019 | Gaidano, Valentina; Circosta, Paola; Cignetti, Alessandro; Houshmand, Mohammad; Vitale, Nicoletta; Sainas, Stefano; Pippione, Agnese; Marraudino, Marilena; Bonaldo, Brigitta; Giorgis, Marta; Boschi, Donatella; Lolli, Marco Lucio; Saglio, Giuseppe | |
| The inhibition of human DHODH by M433 leads to differentiation and apoptosis in acute myeloid leukemia | 2021 | Sainas Stefano, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Gotti Stefano, Saglio Giuseppe., Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio | |
| Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety | 2021 | Sainas S.; Giorgis M.; Circosta P.; Gaidano V.; Bonanni D.; Pippione A.C.; Bagnati R.; Passoni A.; Qiu Y.; Cojocaru C.F.; Canepa B.; Bona A.; Rolando B.; Mishina M.; Ramondetti C.; Buccinna B.; Piccinini M.; Houshmand M.; Cignetti A.; Giraudo E.; Al-Karadaghi S.; Boschi D.; Saglio G.; Lolli M.L. |
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