Sfoglia per Autore
ERK inhibitor LY3214996-based treatment strategies for RAS-driven lung cancer
2021-01-01 Köhler, Jens; Zhao, Yutong; Li, Jiaqi; Gokhale, Prafulla C; Tiv, Hong L; Knott, Aine R; Wilkens, Margaret K; Soroko, Kara M; Lin, Mika; Ambrogio, Chiara; Musteanu, Monica; Ogino, Atsuko; Choi, Jihyun; Bahcall, Magda; Bertram, Arrien A; Chambers, Emily S; Paweletz, Cloud P; Bhagwat, Shripad V; Manro, Jason R; Tiu, Ramon V; Janne, Pasi A
Discoveries in the redox regulation of KRAS
2021-01-01 Maximilian Kramer-Drauberg; Chiara Ambrogio
Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non-Small Cell Lung Cancer
2022-01-01 Ricciuti, Biagio; Son, Jieun; Okoro, Jeffrey J; Mira, Alessia; Patrucco, Enrico; Eum, Yoonji; Wang, Xinan; Paranal, Raymond; Wang, Haiyun; Lin, Mika; Haikala, Heidi M; Li, Jiaqi; Xu, Yue; Alessi, Joao Victor; Chhoeu, Chhayheng; Redig, Amanda J; Köhler, Jens; Dholakia, Kshiti H; Chen, Yunhan; Richard, Elodie; Nokin, Marie-Julie; Santamaria, David; Gokhale, Prafulla C; Awad, Mark M; Jänne, Pasi A; Ambrogio, Chiara
Dissecting the clinicopathologic, genomic, and immunophenotypic correlates of KRASG12D-mutated non-small-cell lung cancer
2022-01-01 Ricciuti, B; Alessi, J V; Elkrief, A; Wang, X; Cortellini, A; Li, Y Y; Vaz, V R; Gupta, H; Pecci, F; Barrichello, A; Lamberti, G; Nguyen, T; Lindsay, J; Sharma, B; Felt, K; Rodig, S J; Nishino, M; Sholl, L M; Barbie, D A; Negrao, M V; Zhang, J; Cherniack, A D; Heymach, J V; Meyerson, M; Ambrogio, C; Jänne, P A; Arbour, K C; Pinato, D J; Skoulidis, F; Schoenfeld, A J; Awad, M M; Luo, J
Tyrosine phosphatases regulate resistance to ALK inhibitors in ALK+ anaplastic large cell lymphoma
2022-01-01 Karaca Atabay, Elif; Mecca, Carmen; Wang, Qi; Ambrogio, Chiara; Mota, Ines; Prokoph, Nina; Mura, Giulia; Martinengo, Cinzia; Patrucco, Enrico; Leonardi, Giulia; Hossa, Jessica; Pich, Achille; Mologni, Luca; Gambacorti-Passerini, Carlo B; Brugieres, Laurence; Geoerger, Birgit; Turner, Suzanne D; Voena, Claudia; Cheong, Taek-Chin; Chiarle, Roberto
How to manage KRAS G12C-mutated advanced non-small-cell lung cancer
2022-01-01 Ricciuti, Biagio; Mira, Alessia; Andrini, Elisa; Scaparone, Pietro; Michelina, Sandra Vietti; Pecci, Federica; Cantini, Luca; De Giglio, Andrea; Lamberti, Giuseppe; Ambrogio, Chiara; Metro, Giulio
Genomic Profiling Identifies Putative Pathogenic Alterations in NSCLC Brain Metastases
2022-01-01 Nicoś, Marcin; Harbers, Luuk; Patrucco, Enrico; Kramer-Drauberg, Maximilian; Zhang, Xiaolu; Voena, Claudia; Kowalczyk, Anna; Bożyk, Aleksandra; Pęksa, Rafał; Jarosz, Bożena; Szumiło, Justyna; Simonetti, Michele; Żuk, Monika; Wasąg, Bartosz; Reszka, Katarzyna; Duchnowska, Renata; Milanowski, Janusz; Chiarle, Roberto; Bienko, Magda; Krawczyk, Paweł; Jassem, Jacek; Ambrogio, Chiara; Crosetto, Nicola
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis
2022-01-01 Costamagna, Andrea; Natalini, Dora; Leal, Maria del Pilar Camacho; Simoni, Matilde; Gozzelino, Luca; Cappello, Paola; Novelli, Francesco; Ambrogio, Chiara; Defilippi, Paola; Turco, Emilia; Giovannetti, Elisa; Hirsch, Emilio; Cabodi, Sara; Martini, Miriam
How far we have come targeting BRAF-mutant non-small cell lung cancer (NSCLC)
2022-01-01 Tabbo F.; Pisano C.; Mazieres J.; Mezquita L.; Nadal E.; Planchard D.; Pradines A.; Santamaria D.; Swalduz A.; Ambrogio C.; Novello S.; Ortiz-Cuaran S.
Regulation of CD45 phosphatase by oncogenic ALK in anaplastic large cell lymphoma
2022-01-01 Mura, Giulia; Karaca Atabay, Elif; Menotti, Matteo; Martinengo, Cinzia; Ambrogio, Chiara; Giacomello, Gloria; Arigoni, Maddalena; Olivero, Martina; Calogero, Raffaele A; Chiarle, Roberto; Voena, Claudia
Resistance to KRAS G12C Inhibition in Non-small Cell Lung Cancer
2023-01-01 Di Federico, Alessandro; Ricciotti, Ilaria; Favorito, Valentina; Michelina, Sandra Vietti; Scaparone, Pietro; Metro, Giulio; De Giglio, Andrea; Pecci, Federica; Lamberti, Giuseppe; Ambrogio, Chiara; Ricciuti, Biagio
YAP and TAZ orchestrate adaptive resistance to KRAS inhibitors
2023-01-01 Alessia Mira; Chiara Ambrogio
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma
2023-01-01 Mastini, Cristina; Campisi, Marco; Patrucco, Enrico; Mura, Giulia; Ferreira, Antonio; Costa, Carlotta; Ambrogio, Chiara; Germena, Giulia; Martinengo, Cinzia; Peola, Silvia; Mota, Ines; Vissio, Elena; Molinaro, Luca; Arigoni, Maddalena; Olivero, Martina; Calogero, Raffaele; Prokoph, Nina; Tabbò, Fabrizio; Shoji, Brent; Brugieres, Laurence; Geoerger, Birgit; Turner, Suzanne D; Cuesta-Mateos, Carlos; D'Aliberti, Deborah; Mologni, Luca; Piazza, Rocco; Gambacorti-Passerini, Carlo; Inghirami, Giorgio G; Chiono, Valeria; Kamm, Roger D; Hirsch, Emilio; Koch, Raphael; Weinstock, David M; Aster, Jon C; Voena, Claudia; Chiarle, Roberto
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer
2023-01-01 Entrialgo-Cadierno, Rodrigo; Cueto-Ureña, Cristina; Welch, Connor; Feliu, Iker; Macaya, Irati; Vera, Laura; Morales, Xabier; Michelina, Sandra Vietti; Scaparone, Pietro; Lopez, Ines; Darbo, Elodie; Erice, Oihane; Vallejo, Adrian; Moreno, Haritz; Goñi-Salaverri, Ainhoa; Lara-Astiaso, David; Halberg, Nils; Cortes-Dominguez, Ivan; Guruceaga, Elizabeth; Ambrogio, Chiara; Lecanda, Fernando; Vicent, Silve
Exploiting signaling rewiring in cancer cells with co-existing oncogenic drivers
2023-01-01 Chiarle, Roberto; Ambrogio, Chiara
ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
2023-01-01 Bergaggio, Elisa; Tai, Wei-Tien; Aroldi, Andrea; Mecca, Carmen; Landoni, Elisa; Nüesch, Manuel; Mota, Ines; Metovic, Jasna; Molinaro, Luca; Ma, Leyuan; Alvarado, Diego; Ambrogio, Chiara; Voena, Claudia; Blasco, Rafael B; Li, Tongqing; Klein, Daryl; Irvine, Darrell J; Papotti, Mauro; Savoldo, Barbara; Dotti, Gianpietro; Chiarle, Roberto
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer
2023-01-01 Mota, Ines; Patrucco, Enrico; Mastini, Cristina; Mahadevan, Navin R; Thai, Tran C; Bergaggio, Elisa; Cheong, Taek-Chin; Leonardi, Giulia; Karaca-Atabay, Elif; Campisi, Marco; Poggio, Teresa; Menotti, Matteo; Ambrogio, Chiara; Longo, Dario L; Klaeger, Susan; Keshishian, Hasmik; Sztupinszki, Zsófia M; Szallasi, Zoltan; Keskin, Derin B; Duke-Cohan, Jonathan S; Reinhold, Bruce; Carr, Steven A; Wu, Catherine J; Moynihan, Kelly D; Irvine, Darrell J; Barbie, David A; Reinherz, Ellis L; Voena, Claudia; Awad, Mark M; Blasco, Rafael B; Chiarle, Roberto
Biological and targeting differences between the rare KRAS A146T and canonical KRAS mutants in gastric cancer models
2024-01-01 Puliga, Elisabetta; De Bellis, Chiara; Vietti Michelina, Sandra; Capeloa, Tania; Migliore, Cristina; Orrù, Claudia; Baiocchi, Gian Luca; De Manzoni, Giovanni; Pietrantonio, Filippo; Reddavid, Rossella; Fumagalli Romario, Uberto; Ambrogio, Chiara; Corso, Simona; Giordano, Silvia
Novel RAF‐directed approaches to overcome current clinical limits and block the RAS/RAF node
2024-01-01 Scardaci, Rossella; Berlinska, Ewa; Scaparone, Pietro; Vietti Michelina, Sandra; Garbo, Edoardo; Novello, Silvia; Santamaria, David; Ambrogio, Chiara
Cancer Hallmarks: Piecing the Puzzle Together
2024-01-01 Alcolea, Maria P.; Alonso-Curbelo, Direna; Ambrogio, Chiara; Bullman, Susan; Correia, Ana Luísa; Ernst, Aurélie; Halbrook, Christopher J.; Kelly, Gemma L.; Lund, Amanda W.; Quail, Daniela F.; Ruscetti, Marcus; Shema, Efrat; Stromnes, Ingunn M.; Tam, Wai Leong
The Anti-Programmed Cell Death Protein-1/ Programmed Death-Ligand 1 Me-Too Drugs Tsunami: Hard To Be Millennials Among Baby Boomers
In corso di stampa Ferrara, Roberto; Ricciuti, Biagio; Ambrogio, Chiara; Trapani, Dario
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| ERK inhibitor LY3214996-based treatment strategies for RAS-driven lung cancer | 2021 | Köhler, Jens; Zhao, Yutong; Li, Jiaqi; Gokhale, Prafulla C; Tiv, Hong L; Knott, Aine R; Wilkens, Margaret K; Soroko, Kara M; Lin, Mika; Ambrogio, Chiara; Musteanu, Monica; Ogino, Atsuko; Choi, Jihyun; Bahcall, Magda; Bertram, Arrien A; Chambers, Emily S; Paweletz, Cloud P; Bhagwat, Shripad V; Manro, Jason R; Tiu, Ramon V; Janne, Pasi A | |
| Discoveries in the redox regulation of KRAS | 2021 | Maximilian Kramer-Drauberg; Chiara Ambrogio | |
| Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non-Small Cell Lung Cancer | 2022 | Ricciuti, Biagio; Son, Jieun; Okoro, Jeffrey J; Mira, Alessia; Patrucco, Enrico; Eum, Yoonji; Wang, Xinan; Paranal, Raymond; Wang, Haiyun; Lin, Mika; Haikala, Heidi M; Li, Jiaqi; Xu, Yue; Alessi, Joao Victor; Chhoeu, Chhayheng; Redig, Amanda J; Köhler, Jens; Dholakia, Kshiti H; Chen, Yunhan; Richard, Elodie; Nokin, Marie-Julie; Santamaria, David; Gokhale, Prafulla C; Awad, Mark M; Jänne, Pasi A; Ambrogio, Chiara | |
| Dissecting the clinicopathologic, genomic, and immunophenotypic correlates of KRASG12D-mutated non-small-cell lung cancer | 2022 | Ricciuti, B; Alessi, J V; Elkrief, A; Wang, X; Cortellini, A; Li, Y Y; Vaz, V R; Gupta, H; Pecci, F; Barrichello, A; Lamberti, G; Nguyen, T; Lindsay, J; Sharma, B; Felt, K; Rodig, S J; Nishino, M; Sholl, L M; Barbie, D A; Negrao, M V; Zhang, J; Cherniack, A D; Heymach, J V; Meyerson, M; Ambrogio, C; Jänne, P A; Arbour, K C; Pinato, D J; Skoulidis, F; Schoenfeld, A J; Awad, M M; Luo, J | |
| Tyrosine phosphatases regulate resistance to ALK inhibitors in ALK+ anaplastic large cell lymphoma | 2022 | Karaca Atabay, Elif; Mecca, Carmen; Wang, Qi; Ambrogio, Chiara; Mota, Ines; Prokoph, Nina; Mura, Giulia; Martinengo, Cinzia; Patrucco, Enrico; Leonardi, Giulia; Hossa, Jessica; Pich, Achille; Mologni, Luca; Gambacorti-Passerini, Carlo B; Brugieres, Laurence; Geoerger, Birgit; Turner, Suzanne D; Voena, Claudia; Cheong, Taek-Chin; Chiarle, Roberto | |
| How to manage KRAS G12C-mutated advanced non-small-cell lung cancer | 2022 | Ricciuti, Biagio; Mira, Alessia; Andrini, Elisa; Scaparone, Pietro; Michelina, Sandra Vietti; Pecci, Federica; Cantini, Luca; De Giglio, Andrea; Lamberti, Giuseppe; Ambrogio, Chiara; Metro, Giulio | |
| Genomic Profiling Identifies Putative Pathogenic Alterations in NSCLC Brain Metastases | 2022 | Nicoś, Marcin; Harbers, Luuk; Patrucco, Enrico; Kramer-Drauberg, Maximilian; Zhang, Xiaolu; Voena, Claudia; Kowalczyk, Anna; Bożyk, Aleksandra; Pęksa, Rafał; Jarosz, Bożena; Szumiło, Justyna; Simonetti, Michele; Żuk, Monika; Wasąg, Bartosz; Reszka, Katarzyna; Duchnowska, Renata; Milanowski, Janusz; Chiarle, Roberto; Bienko, Magda; Krawczyk, Paweł; Jassem, Jacek; Ambrogio, Chiara; Crosetto, Nicola | |
| Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis | 2022 | Costamagna, Andrea; Natalini, Dora; Leal, Maria del Pilar Camacho; Simoni, Matilde; Gozzelino, Luca; Cappello, Paola; Novelli, Francesco; Ambrogio, Chiara; Defilippi, Paola; Turco, Emilia; Giovannetti, Elisa; Hirsch, Emilio; Cabodi, Sara; Martini, Miriam | |
| How far we have come targeting BRAF-mutant non-small cell lung cancer (NSCLC) | 2022 | Tabbo F.; Pisano C.; Mazieres J.; Mezquita L.; Nadal E.; Planchard D.; Pradines A.; Santamaria D.; Swalduz A.; Ambrogio C.; Novello S.; Ortiz-Cuaran S. | |
| Regulation of CD45 phosphatase by oncogenic ALK in anaplastic large cell lymphoma | 2022 | Mura, Giulia; Karaca Atabay, Elif; Menotti, Matteo; Martinengo, Cinzia; Ambrogio, Chiara; Giacomello, Gloria; Arigoni, Maddalena; Olivero, Martina; Calogero, Raffaele A; Chiarle, Roberto; Voena, Claudia | |
| Resistance to KRAS G12C Inhibition in Non-small Cell Lung Cancer | 2023 | Di Federico, Alessandro; Ricciotti, Ilaria; Favorito, Valentina; Michelina, Sandra Vietti; Scaparone, Pietro; Metro, Giulio; De Giglio, Andrea; Pecci, Federica; Lamberti, Giuseppe; Ambrogio, Chiara; Ricciuti, Biagio | |
| YAP and TAZ orchestrate adaptive resistance to KRAS inhibitors | 2023 | Alessia Mira; Chiara Ambrogio | |
| Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma | 2023 | Mastini, Cristina; Campisi, Marco; Patrucco, Enrico; Mura, Giulia; Ferreira, Antonio; Costa, Carlotta; Ambrogio, Chiara; Germena, Giulia; Martinengo, Cinzia; Peola, Silvia; Mota, Ines; Vissio, Elena; Molinaro, Luca; Arigoni, Maddalena; Olivero, Martina; Calogero, Raffaele; Prokoph, Nina; Tabbò, Fabrizio; Shoji, Brent; Brugieres, Laurence; Geoerger, Birgit; Turner, Suzanne D; Cuesta-Mateos, Carlos; D'Aliberti, Deborah; Mologni, Luca; Piazza, Rocco; Gambacorti-Passerini, Carlo; Inghirami, Giorgio G; Chiono, Valeria; Kamm, Roger D; Hirsch, Emilio; Koch, Raphael; Weinstock, David M; Aster, Jon C; Voena, Claudia; Chiarle, Roberto | |
| The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer | 2023 | Entrialgo-Cadierno, Rodrigo; Cueto-Ureña, Cristina; Welch, Connor; Feliu, Iker; Macaya, Irati; Vera, Laura; Morales, Xabier; Michelina, Sandra Vietti; Scaparone, Pietro; Lopez, Ines; Darbo, Elodie; Erice, Oihane; Vallejo, Adrian; Moreno, Haritz; Goñi-Salaverri, Ainhoa; Lara-Astiaso, David; Halberg, Nils; Cortes-Dominguez, Ivan; Guruceaga, Elizabeth; Ambrogio, Chiara; Lecanda, Fernando; Vicent, Silve | |
| Exploiting signaling rewiring in cancer cells with co-existing oncogenic drivers | 2023 | Chiarle, Roberto; Ambrogio, Chiara | |
| ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells | 2023 | Bergaggio, Elisa; Tai, Wei-Tien; Aroldi, Andrea; Mecca, Carmen; Landoni, Elisa; Nüesch, Manuel; Mota, Ines; Metovic, Jasna; Molinaro, Luca; Ma, Leyuan; Alvarado, Diego; Ambrogio, Chiara; Voena, Claudia; Blasco, Rafael B; Li, Tongqing; Klein, Daryl; Irvine, Darrell J; Papotti, Mauro; Savoldo, Barbara; Dotti, Gianpietro; Chiarle, Roberto | |
| ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer | 2023 | Mota, Ines; Patrucco, Enrico; Mastini, Cristina; Mahadevan, Navin R; Thai, Tran C; Bergaggio, Elisa; Cheong, Taek-Chin; Leonardi, Giulia; Karaca-Atabay, Elif; Campisi, Marco; Poggio, Teresa; Menotti, Matteo; Ambrogio, Chiara; Longo, Dario L; Klaeger, Susan; Keshishian, Hasmik; Sztupinszki, Zsófia M; Szallasi, Zoltan; Keskin, Derin B; Duke-Cohan, Jonathan S; Reinhold, Bruce; Carr, Steven A; Wu, Catherine J; Moynihan, Kelly D; Irvine, Darrell J; Barbie, David A; Reinherz, Ellis L; Voena, Claudia; Awad, Mark M; Blasco, Rafael B; Chiarle, Roberto | |
| Biological and targeting differences between the rare KRAS A146T and canonical KRAS mutants in gastric cancer models | 2024 | Puliga, Elisabetta; De Bellis, Chiara; Vietti Michelina, Sandra; Capeloa, Tania; Migliore, Cristina; Orrù, Claudia; Baiocchi, Gian Luca; De Manzoni, Giovanni; Pietrantonio, Filippo; Reddavid, Rossella; Fumagalli Romario, Uberto; Ambrogio, Chiara; Corso, Simona; Giordano, Silvia | |
| Novel RAF‐directed approaches to overcome current clinical limits and block the RAS/RAF node | 2024 | Scardaci, Rossella; Berlinska, Ewa; Scaparone, Pietro; Vietti Michelina, Sandra; Garbo, Edoardo; Novello, Silvia; Santamaria, David; Ambrogio, Chiara | |
| Cancer Hallmarks: Piecing the Puzzle Together | 2024 | Alcolea, Maria P.; Alonso-Curbelo, Direna; Ambrogio, Chiara; Bullman, Susan; Correia, Ana Luísa; Ernst, Aurélie; Halbrook, Christopher J.; Kelly, Gemma L.; Lund, Amanda W.; Quail, Daniela F.; Ruscetti, Marcus; Shema, Efrat; Stromnes, Ingunn M.; Tam, Wai Leong | |
| The Anti-Programmed Cell Death Protein-1/ Programmed Death-Ligand 1 Me-Too Drugs Tsunami: Hard To Be Millennials Among Baby Boomers | In corso di stampa | Ferrara, Roberto; Ricciuti, Biagio; Ambrogio, Chiara; Trapani, Dario |
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