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Mostrati risultati da 46 a 79 di 79
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A Braf kinase-inactive mutant induces lung adenocarcinoma 2017 Nieto P.; Ambrogio C.; Esteban-Burgos L.; Gomez-Lopez G.; Blasco M.T.; Yao Z.; Marais R.; Rosen N.; Chiarle R.; Pisano D.G.; Barbacid M.; Santamaria D.
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells 2017 Compagno, Mara; Wang, Qi; Pighi, Chiara; Cheong, Taek-Chin; Meng, Fei-Long; Poggio, Teresa; Yeap, Leng-Siew; Karaca, Elif; Blasco, Rafael B.; Langellotto, Fernanda; Ambrogio, Chiara; Voena, Claudia; Wiestner, Adrian; Kasar, Siddha N.; Brown, Jennifer R.; Sun, Jing; Wu, Catherine J.; Gostissa, Monica; Alt, Frederick W.; Chiarle, Roberto
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma 2016 Ambrogio C.; Gomez-Lopez G.; Falcone M.; Vidal A.; Nadal E.; Crosetto N.; Blasco R.B.; Fernandez-Marcos P.J.; Sanchez-Cespedes M.; Ren X.; Wang Z.; Ding K.; Hidalgo M.; Serrano M.; Villanueva A.; Santamaraa D.; Barbacid M.
Redundant and non-redundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice 2016 Choudhari, Ramesh; Minero, Valerio Giacomo; Menotti, Matteo; Pulito, Roberta; Brakebusch, Cord; Compagno, Mara; Voena, Claudia; Ambrogio, Chiara; Chiarle, Roberto
Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency 2016 Ceccon, M; Merlo, M E Boggio; Mologni, L.; Poggio, T.; Varesio, L.M.; Menotti, M.; Bombelli, S.; Rigolio, R.; Manazza, A.D.; Di Giacomo, F.; Ambrogio, C.; Giudici, G.; Casati, C.; Mastini, C.; Compagno, M.; Turner, S.D.; Gambacorti-Passerini, C.; Chiarle, R. ; Voena, C.
Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice 2015 Lopez-Contreras A.J.; Specks J.; Barlow J.H.; Ambrogio C.; Desler C.; Vikingsson S.; Rodrigo-Perez S.; Green H.; Rasmussen L.J.; Murga M.; Nussenzweig A.; Fernandez-Capetillo O.
Efficacy of a Cancer Vaccine against ALK-Rearranged Lung Tumors 2015 Voena, Claudia; Menotti, Matteo; Mastini, Cristina; Di Giacomo, Filomena; Longo, Dario Livio; Castella, Barbara; Merlo, Maria Elena Boggio; Ambrogio, Chiara; Wang, Qi; Minero, Valerio Giacomo; Poggio, Teresa; Martinengo, Cinzia; D'Amico, Lucia; Panizza, Elena; Mologni, Luca; Cavallo, Federica; Altruda, Fiorella; Butaney, Mohit; Capelletti, Marzia; Inghirami, Giorgio; Jänne, Pasi A; Chiarle, Roberto
Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage 2015 Garcia-Beccaria M.; Martinez P.; Mendez-Pertuz M.; Martinez S.; Blanco-Aparicio C.; Canamero M.; Mulero F.; Ambrogio C.; Flores J.M.; Megias D.; Barbacid M.; Pastor J.; Blasco M.A.
Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts 2014 Ambrogio, Chiara*; Carmona, Francisco J.; Vidal, August; Falcone, Mattia; Nieto, Patricia; Romero, Octavio A.; Puertas, Sara; Vizoso, Miguel; Nadal, Ernest; Poggio, Teresa; Sánchez-Céspedes, Montserrat; Esteller, Manel; Mulero, Francisca; Voena, Claudia; Chiarle, Roberto; Barbacid, Mariano; Santamaría, David; Villanueva, Alberto
ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis 2014 Martinengo, Cinzia; Poggio, Teresa; Menotti, Matteo; Scalzo, Maria Stella; Mastini, Cristina; Ambrogio, Chiara; Pellegrino, Elisa; Riera, Ludovica; Piva, Roberto; Ribatti, Domenico; Pastorino, Fabio; Perri, Patrizia; Ponzoni, Mirco; Wang, Qi; Voena, Claudia; Chiarle, Roberto
Simple and Rapid InVivo Generation of Chromosomal Rearrangements using CRISPR/Cas9 Technology 2014 Blasco, Rafael B; Karaca, Elif; Ambrogio, Chiara; Cheong, Taek-Chin; Karayol, Emre; Minero, Valerio G.; Voena, Claudia; Chiarle, Roberto
Lentiviral-based approach for the validation of cancer therapeutic targets in vivo 2014 Ambrogio C.; Stern P.; Scuoppo C.; Kranz H.; Barbacid M.; Santamaria D.
The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1. 2013 Voena C;Di Giacomo F;Panizza E;D'Amico L;Boccalatte FE;Pellegrino E;Todaro M;Recupero D;Tabbò F;Ambrogio C;Martinengo C;Bonello L;Pulito R;Hamm J;Chiarle R;Cheng M;Ruggeri B;Medico E;Inghirami G
PPP4R2 regulates neuronal cell differentiation and survival, functionally cooperating with SMN. 2012 Bosio Y; Berto G; Camera P; Bianchi F; Ambrogio C; Claus P; Di Cunto F
Selective Therapeutic Targeting of the Anaplastic Lymphoma Kinase With Liposomal siRNA Induces Apoptosis and Inhibits Angiogenesis in Neuroblastoma. 2011 Di Paolo D; Ambrogio C; Pastorino F; Brignole C; Martinengo C; Carosio R; Loi M; Pagnan G; Emionite L; Cilli M; Ribatti D; Allen TM; Chiarle R; Ponzoni M; Perri P.
Involvement of Grb2 adaptor protein in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated signaling and anaplastic large cell lymphoma growth. 2010 Riera L; Lasorsa E; Ambrogio C; Surrenti N; Voena C; Chiarle R.
Expression of IFNgammaR2 mutated in a dileucine internalization motif reinstates IFNgamma signaling and apoptosis in human T lymphocytes 2010 Boselli D; Ragimbeau J; Orlando L; Cappello P; Capello M; Ambrogio C; Chiarle R; Marsili G; Battistini A; Giovarelli M; Pellegrini S; Novelli F.
MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling. 2010 Gonzalo P; Guadamillas MC; Hernández-Riquer MV; Pollán A; Grande-García A; Bartolomé RA; Vasanji A; Ambrogio C; Chiarle R; Teixidó J; Risteli J; Apte SS; del Pozo MA; Arroyo AG.
NPM-ALK oncogenic tyrosine kinase controls T-cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells 2009 Ambrogio C; Martinengo C; Voena C; Tondat F; Riera L; di Celle PF; Inghirami G; Chiarle R.
Leukocyte transmigration is modulated by chemokine-mediated PI3Kgamma-dependent phosphorylation of vimentin 2009 Barberis L; Pasquali C; Bertschy-Meier D; Cuccurullo A; Costa C; Ambrogio C; Vilbois F; Chiarle R; Wymann M; Altruda F; Rommel C; Hirsch E.
The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation 2008 Ambrogio C; Voena C; Manazza AD; Martinengo C; Costa C; Kirchhausen T; Hirsch E; Inghirami G; Chiarle R.
The anaplastic lymphoma kinase in the pathogenesis of cancer 2008 R. CHIARLE; C. VOENA; C. AMBROGIO; R. PIVA; G. INGHIRAMI
Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner 2008 Crosetto N.; Bienko M.; Hibbert R.G.; Perica T.; Ambrogio C.; Kensche T.; Hofmann K.; Sixma T.K.; Dikic I.
The anaplastic lymphoma kinase is an effective oncoantigen for lymphoma vaccination 2008 Chiarle R; Martinengo C; Mastini C; Ambrogio C; D’Escamard V; Forni G; Inghirami G
TTC3 protein inhibits neuronal differentiation through RhoA and CITRON dependent mechanism 2008 GE Berto; P Camera; C Ambrogio; CS Dotti; F Di Cunto
TTC3 protein inhibits neuronal differentiation through a RhoA dependent mechanism 2008 GE Berto; P Camera; C Ambrogio; F Di Cunto
The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration 2007 VOENA C; CONTE C; AMBROGIO C; BOERI ERBA E; BOCCALATTE F; MOHAMMED S; JENSEN ON; PALESTRO G; INGHIRAMI G; CHIARLE R
Molecola perturbation of IFNγR2 internalization reinstates T cell sensitività to the IFNγ/STAT1 signaling pathway in vitro and in vivo. 5th 2007 Boselli D; Ragimbeau J; Orlando L; Cappello P; Bernabei P; Ambrogio C; Chiarle R; Pellegrini S; Giovarelli M; Novelli F.
The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase 2007 BERTO G; CAMERA P; FUSCO C; IMARISIO S; AMBROGIO C; CHIARLE R; SILENGO L; DI CUNTO F
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma 2007 COSTA C; BARBERIS L; AMBROGIO C; MANAZZA AD; PATRUCCO E; AZZOLINO O; NEILSEN PO; CIRAOLO E; ALTRUDA F; PRESTWICH GD; CHIARLE R; WYMANN M; RIDLEY A; HIRSCH E
The Tyrosine Phosphatase SHP2 Interacts with NPM-ALK and Regulates Anaplastic Lymphoma Cell Growth and Migration. 2006 Voena C; Conte C; Ambrogio C; Boeri Erba E; Boccalatte F; Mohammed S; Jensen ON; Inghirami G; Chiarle R.
Ablation of oncogenic ALK is a viable therapeutic approach fAblation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas 2006 PIVA R; CHIARLE R; MANAZZA AD; TAULLI R; SIMMONS W; AMBROGIO C; D'ESCAMARD V; PELLEGRINO E; PONZETTO C; PALESTRO G; INGHIRAMI G
Identification of genomic and proteomic signatures in lymphomas by inducible shRNA 2005 R Piva; E Pellegrino; M Mattioli; C Voena; C Conte; F Boccalatte; C Ambrogio; A Manazza; A Neri; R Chiarle; G Inghirami
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 2005 AMBROGIO C; VOENA C; MANAZZA AD; PIVA R; RIERA L; BARBERIS L; COSTA C; TARONE G; DEFILIPPI P; HIRSCH E; ERBA EB; MOHAMMED S; JENSEN ON; PALESTRO G; INGHIRAMI G; CHIARLE R.
Mostrati risultati da 46 a 79 di 79
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