HOUSHMAND, MOHAMMAD

HOUSHMAND, MOHAMMAD  

SCIENZE CLINICHE E BIOLOGICHE  

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A differentiating and apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor 2021 Stefano Sainas, Paola Circosta, Marta Giorgis, Agnese Chiara Pippione, Marilena Marraudino, Mohammad Houshmand, Brigitta Bonaldo, Valentina Gaidano, Alessandro Cignetti, Stefano Gotti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
A new pro-apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor 2021 Sainas Sainas, Paola Circosta, Noemi Villella, Elena Martino, Agnese Chiara Pippione, Mohammad Houshmand, Marta Giorgis, Valentina Gaidano, Alessandro Cignetti, Caterina Peraldo Neia, Giovanna Chiorino, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli.
Apoptotic and differentiating therapy for AML using potent human dihydroorotate dehydrogenase inhibitor 2021 Sainas Sainas, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lolli
Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia 2021 -
Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia 2022 Houshmand, Mohammad; Vitale, Nicoletta; Orso, Francesca; Cignetti, Alessandro; Molineris, Ivan; Gaidano, Valentina; Sainas, Stefano; Giorgis, Marta; Boschi, Donatella; Fava, Carmen; Passoni, Alice; Gai, Marta; Geuna, Massimo; Sora, Federica; Iurlo, Alessandra; Abruzzese, Elisabetta; Breccia, Massimo; Mulas, Olga; Caocci, Giovanni; Castagnetti, Fausto; Taverna, Daniela; Oliviero, Salvatore; Pane, Fabrizio; Lolli, Marco Lucio; Circosta, Paola; Saglio, Giuseppe
Hydroxylated heterocycles as a bioisosteric tool to Modulate the carboxylic function into design potent human Dihydroorotate Dehydrogenase inhibitors 2021 Stefano Sainas, Paola Circosta, Agnese Chiara Pippione, Mohammad Houshmand, Marta Giorgis, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Donatella Boschi, Marco Lucio Lolli
Meds433, a New Dihydroorotate Dehydrogenase Inhibitor, Induces Apoptosis and Differentiation in Acute Myeloid Leukemia 2019 Gaidano, Valentina; Circosta, Paola; Cignetti, Alessandro; Houshmand, Mohammad; Vitale, Nicoletta; Sainas, Stefano; Pippione, Agnese; Marraudino, Marilena; Bonaldo, Brigitta; Giorgis, Marta; Boschi, Donatella; Lolli, Marco Lucio; Saglio, Giuseppe
Nanocarriers as magic bullets in the treatment of leukemia 2020 Houshmand M.; Garello F.; Circosta P.; Stefania R.; Aime S.; Saglio G.; Giachino C.
Shedding Light on Targeting Chronic Myeloid Leukemia Stem Cells 2021 Houshmand, Mohammad; Kazemi, Alireza; Anjam Najmedini, Ali; Ali, Muhammad Shahzad; Gaidano, Valentina; Cignetti, Alessandro; Fava, Carmen; Cilloni, Daniela; Saglio, Giuseppe; Circosta, Paola
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety 2021 Sainas S.; Giorgis M.; Circosta P.; Gaidano V.; Bonanni D.; Pippione A.C.; Bagnati R.; Passoni A.; Qiu Y.; Cojocaru C.F.; Canepa B.; Bona A.; Rolando B.; Mishina M.; Ramondetti C.; Buccinna B.; Piccinini M.; Houshmand M.; Cignetti A.; Giraudo E.; Al-Karadaghi S.; Boschi D.; Saglio G.; Lolli M.L.
Targeting chronic myeloid leukemia stem/progenitor cells using venetoclax-loaded immunoliposome 2021 Houshmand M.; Garello F.; Stefania R.; Gaidano V.; Cignetti A.; Spinelli M.; Fava C.; Zarif M.N.; Galimberti S.; Pungolino E.; Annunziata M.; Luciano L.; Specchia G.; Bocchia M.; Binotto G.; Bonifacio M.; Martino B.; Pregno P.; Stagno F.; Iurlo A.; Russo S.; Aime S.; Circosta P.; Saglio G.
The inhibition of human DHODH by M433 leads to differentiation and apoptosis in acute myeloid leukemia 2021 Sainas Stefano, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Gotti Stefano, Saglio Giuseppe., Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio
The synergism between DHODH inhibitors and dipyridamole leads to metabolic lethality in acute myeloid leukemia 2021 Gaidano V.; Houshmand M.; Vitale N.; Carra G.; Morotti A.; Tenace V.; Rapelli S.; Sainas S.; Pippione A.C.; Giorgis M.; Boschi D.; Lolli M.L.; Cilloni D.; Cignetti A.; Saglio G.; Circosta P.