Nome |
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NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria, file e27ce427-b4cc-2581-e053-d805fe0acbaa
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370
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Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues., file e27ce426-d5c3-2581-e053-d805fe0acbaa
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262
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Thymopentin down-regulates both activity and expression of iNOS in blood cells of Sézary syndrome patients, file e27ce427-b229-2581-e053-d805fe0acbaa
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256
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Amodiaquine analogues containing NO-donor substructures: Synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria, file e27ce426-bdc3-2581-e053-d805fe0acbaa
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250
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New nitric oxide or hydrogen sulfide releasing aspirins, file e27ce426-d99c-2581-e053-d805fe0acbaa
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245
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Tandem Mass Spectrometry of Nitric Oxide and Hydrogen Sulfide Releasing Aspirins: A Hint into Activity Behavior, file e27ce42b-105c-2581-e053-d805fe0acbaa
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233
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Leishmanicidal Activity of Novel Synthetic Furoxan and Benzofuroxan Derivatives, file e27ce429-8b1b-2581-e053-d805fe0acbaa
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219
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Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity, file e27ce42c-26e7-2581-e053-d805fe0acbaa
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219
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Searching for new NO-donor aspirin-like molecules: furoxanylacyl derivatives of salicylic acid and related furazans, file e27ce426-dd5a-2581-e053-d805fe0acbaa
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203
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Phenylsulfonylfuroxans as Modulators of Multidrug-Resistance-Associated Protein-1 and P-Glycoprotein, file e27ce426-c64d-2581-e053-d805fe0acbaa
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196
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Doxorubicin-antioxidant multitarget drugs, file e27ce426-f93b-2581-e053-d805fe0acbaa
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144
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Synthesis and Biological Evaluation of N2-Substituted 2,4-Diamino-6-cyclohexylmethoxy-5-nitrosopyrimidines and Related 5-Cyano-NNO-azoxy Derivatives as Cyclin-Dependent Kinase 2 (CDK2) Inhibitors, file e27ce429-3fcd-2581-e053-d805fe0acbaa
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127
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Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors, file e27ce42c-8704-2581-e053-d805fe0acbaa
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126
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Thermosensitive nanocomposite hydrogels for intravitreal delivery of cefuroxime, file e27ce42e-c902-2581-e053-d805fe0acbaa
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122
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Molecular dynamics simulations reveal the determinants of cyclin-dependent kinase 2 inhibition by 5-nitrosopyrimidine derivatives, file e27ce42f-a0c5-2581-e053-d805fe0acbaa
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113
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Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis, file e27ce429-b98b-2581-e053-d805fe0acbaa
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105
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Synthesis, physico-chemical characterization, andbiological activities of new carnosine derivatives stablein human serum as potential neuroprotective agents, file e27ce426-c650-2581-e053-d805fe0acbaa
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103
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Anti-pseudomonas activity of 3-nitro-4-phenylfuroxan, file e27ce42d-8dfe-2581-e053-d805fe0acbaa
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98
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Mitochondrial delivery of phenol substructure triggers mitochondrial depolarization and apoptosis of cancer cells, file e27ce42c-f044-2581-e053-d805fe0acbaa
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84
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New tetrahydroisoquinoline derivatives overcome pgp activity in brain-blood barrier and glioblastoma multiforme in vitro, file e27ce42c-d292-2581-e053-d805fe0acbaa
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77
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A multi-photoresponsive molecular-hybrid for dual-modal photoinactivation of cancer cells, file e27ce427-03dc-2581-e053-d805fe0acbaa
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76
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New praziquantel derivatives containing NO-donor furoxans and related furazans as active agents against Schistosoma mansoni, file e27ce427-03db-2581-e053-d805fe0acbaa
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74
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New nitric oxide or hydrogen sulfide releasing aspirins, file e27ce426-d99d-2581-e053-d805fe0acbaa
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72
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Doxorubicin-antioxidant multitarget drugs, file e27ce426-f93a-2581-e053-d805fe0acbaa
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70
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One molecule two goals: A selective P-glycoprotein modulator increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells, file e27ce431-6e5a-2581-e053-d805fe0acbaa
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70
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Phenylsulfonylfuroxans as Modulators of Multidrug-Resistance-Associated Protein-1 and P-Glycoprotein, file e27ce426-c64c-2581-e053-d805fe0acbaa
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59
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A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity, file e27ce426-b440-2581-e053-d805fe0acbaa
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57
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Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity, file e27ce426-c49d-2581-e053-d805fe0acbaa
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50
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Synthesis and in vitro antimicrobial activities of new (cyano-NNO-azoxy)pyrazole derivatives, file e27ce426-bdcc-2581-e053-d805fe0acbaa
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40
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Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells, file e27ce429-141a-2581-e053-d805fe0acbaa
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38
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Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells, file e27ce433-4651-2581-e053-d805fe0acbaa
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37
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New furoxan derivatives for the treatment of ocular hypertension, file e27ce42b-615d-2581-e053-d805fe0acbaa
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36
|
Direct introduction of cyano group on furoxan ring, file e27ce42c-6ab8-2581-e053-d805fe0acbaa
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36
|
Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation, file e27ce42d-c537-2581-e053-d805fe0acbaa
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35
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A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression, file e27ce42a-1088-2581-e053-d805fe0acbaa
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32
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New tetrahydroisoquinoline-based P-glycoprotein modulators: Decoration of the biphenyl core gives selective ligands, file e27ce42d-8df5-2581-e053-d805fe0acbaa
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32
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Furoxan nitric oxide donors disperse Pseudomonas aeruginosa biofilms, accelerate growth, and repress pyoverdine production, file e27ce42b-e9f3-2581-e053-d805fe0acbaa
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31
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Structure-Activity Relationship Studies on Tetrahydroisoquinoline Derivatives: [4′-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol] (MC70) Conjugated through Flexible Alkyl Chains with Furazan Moieties Gives Rise to Potent and Selective Ligands of P-glycoprotein, file e27ce42a-1188-2581-e053-d805fe0acbaa
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28
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New furoxan derivatives for the treatment of ocular hypertension, file e27ce42b-15a7-2581-e053-d805fe0acbaa
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28
|
gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension, file e27ce42c-8ff0-2581-e053-d805fe0acbaa
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25
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Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis, file e27ce429-f403-2581-e053-d805fe0acbaa
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22
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Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity, file e27ce426-c49c-2581-e053-d805fe0acbaa
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21
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Direct introduction of cyano group on furoxan ring, file e27ce42c-3791-2581-e053-d805fe0acbaa
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21
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EFFICIENTLY TARGETING DRUG EFFLUX THROUGH MODULATION OF P-GLYCOPROTEIN ACTIVITY BY SMALL MOLECULES: DESIGN, BIOLOGICAL AND COMPUTATIONAL STUDY., file e27ce42f-0382-2581-e053-d805fe0acbaa
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19
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Synthesis and Biological Evaluation of N2-Substituted 2,4-Diamino-6-cyclohexylmethoxy-5-nitrosopyrimidines and Related 5-Cyano-NNO-azoxy Derivatives as Cyclin-Dependent Kinase 2 (CDK2) Inhibitors, file e27ce429-459c-2581-e053-d805fe0acbaa
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13
|
Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells, file e27ce42e-114b-2581-e053-d805fe0acbaa
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12
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One molecule two goals: A selective P-glycoprotein modulator increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells, file e27ce431-259f-2581-e053-d805fe0acbaa
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6
|
Searching for new NO-donor aspirin-like molecules: furoxanylacyl derivatives of salicylic acid and related furazans, file e27ce427-cd40-2581-e053-d805fe0acbaa
|
4
|
New tetrahydroisoquinoline-based P-glycoprotein modulators: Decoration of the biphenyl core gives selective ligands, file e27ce42c-f046-2581-e053-d805fe0acbaa
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4
|
Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells, file e27ce42e-83c9-2581-e053-d805fe0acbaa
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4
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Overcoming Multidrug Resistance (MDR): Design, Biological Evaluation and Molecular Modelling Studies of 2,4-Substituted Quinazoline Derivatives, file c8082950-d9bb-4ca1-9c4f-ef6f810d1fe9
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3
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A multi-photoresponsive molecular-hybrid for dual-modal photoinactivation of cancer cells, file e27ce428-589d-2581-e053-d805fe0acbaa
|
3
|
New furoxan derivatives for the treatment of ocular hypertension, file e27ce42b-615c-2581-e053-d805fe0acbaa
|
3
|
Furoxan nitric oxide donors disperse Pseudomonas aeruginosa biofilms, accelerate growth, and repress pyoverdine production, file e27ce42b-e9f2-2581-e053-d805fe0acbaa
|
3
|
NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria, file e27ce433-5823-2581-e053-d805fe0acbaa
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3
|
Comparative Study of Different H2S Donors as Vasodilators and Attenuators of Superoxide-Induced Endothelial Damage, file e80b50e2-8b98-45e7-9ee5-3d72ab9566e8
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3
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Unsymmetrically Substituted Furoxans. Part 19. Methyl and Phenylfuroxansulfonic Acids and Related Sulfonamides, file e27ce426-b5e7-2581-e053-d805fe0acbaa
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2
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Amodiaquine analogues containing NO-donor substructures: Synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria, file e27ce426-bdc4-2581-e053-d805fe0acbaa
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2
|
Synthesis, physico-chemical characterization, andbiological activities of new carnosine derivatives stablein human serum as potential neuroprotective agents, file e27ce426-c64f-2581-e053-d805fe0acbaa
|
2
|
Doxorubicin-antioxidant multitarget drugs, file e27ce426-f93c-2581-e053-d805fe0acbaa
|
2
|
New praziquantel derivatives containing NO-donor furoxans and related furazans as active agents against Schistosoma mansoni, file e27ce428-5897-2581-e053-d805fe0acbaa
|
2
|
gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension, file e27ce42c-3c79-2581-e053-d805fe0acbaa
|
2
|
A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity, file e27ce426-b43f-2581-e053-d805fe0acbaa
|
1
|
Synthesis and in vitro antimicrobial activities of new (cyano-NNO-azoxy)pyrazole derivatives, file e27ce426-bdcb-2581-e053-d805fe0acbaa
|
1
|
Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity, file e27ce426-c49b-2581-e053-d805fe0acbaa
|
1
|
New nitric oxide or hydrogen sulfide releasing aspirins, file e27ce426-d99e-2581-e053-d805fe0acbaa
|
1
|
Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues., file e27ce427-ccc5-2581-e053-d805fe0acbaa
|
1
|
Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells, file e27ce429-1d06-2581-e053-d805fe0acbaa
|
1
|
NO-Donor Dihydroartemisinin Derivatives as Multitarget Agents for the Treatment of Cerebral Malaria, file e27ce42a-8cbe-2581-e053-d805fe0acbaa
|
1
|
Direct introduction of cyano group on furoxan ring, file e27ce42c-22a4-2581-e053-d805fe0acbaa
|
1
|
Anti-pseudomonas activity of 3-nitro-4-phenylfuroxan, file e27ce42d-8dff-2581-e053-d805fe0acbaa
|
1
|
Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation, file e27ce42d-c53a-2581-e053-d805fe0acbaa
|
1
|
Molecular dynamics simulations reveal the determinants of cyclin-dependent kinase 2 inhibition by 5-nitrosopyrimidine derivatives, file e27ce42f-037e-2581-e053-d805fe0acbaa
|
1
|
Totale |
4645 |