MARTINO, ELENA
MARTINO, ELENA
SCIENZA E TECNOLOGIA DEL FARMACO
A new pro-apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor
2021-01-01 Sainas Sainas, Paola Circosta, Noemi Villella, Elena Martino, Agnese Chiara Pippione, Mohammad Houshmand, Marta Giorgis, Valentina Gaidano, Alessandro Cignetti, Caterina Peraldo Neia, Giovanna Chiorino, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli.
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent
2024-01-01 Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M.; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L.; Miggiano, Riccardo
Design and synthesis of a library of pyrazolo[1,5-a]pyridine fluorophores for developing new fluorescent probes
2021-01-01 Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Donatella Boschi, Bente Frølund, Marco Lucio Lolli
Design of new human Dihydroorotate Dehydrogenase inhibitors: amide bioisosterism in MEDS433 optimization
2021-01-01 Martino Elena, Villella Noemi, Vigato Chiara, Cerrina Matteo, Bersani Matteo, Giorgis Marta, Sainas Stefano, Boschi Donatella, Lolli Marco Lucio
Develop of new fluorescent probe to target hDHODH enzyme
2022-01-01 Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Agnese Chiara Pippione, Marta Giorgis, Donatella Boschi, Bente Frølund, Marco Lucio Lolli
Improving the fluorescent profile of pyrazolo [1,5-a]pyridine fluorophores for developing new fluorescent probes
2022-01-01 Elena Martino, Noemi Villella, Stefano Sainas, Francesco Bavo, Claudio Garino, Simona Mattiussi, Agnese Chiara Pippione, Marta Giorgis, Donatella Boschi, Bente Frølund, Marco Lucio Lolli.
Investigation of the central core of MEDS433: A Bioisosteric voyage into the Amide's Role
2024-01-01 Elena Martino, Stefano Sainas, Iole Manella, Marta Alberti, Marta Giorgis, Paola Circosta, Donatella Boschi and Marco Lucio Lolli
Investigation of the central core of MEDS433: A Bioisosteric voyage into the Amide's Role.
2024-01-01 Elena Martino, Stefano Sainas, Marta Alberti, Iole Mannella, Marta Giorgis, Paola Circosta, Donatella Boschi, Marco Lucio Lolli
Radiosynthesis of [18F]brequinar for in vivo PET imaging of hDHODH for potential studies of acute myeloid leukemia and cancers
2024-01-01 Sainas, Stefano; Banka, Vinay Kumar; Martino, Elena; Wang, Jiacheng; Lolli, Marco Lucio; Ding, Yu-Shin
Synthesis of [18F] Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase
2019-01-01 Elena Martino, Stefano Sainas, Agnese Chiara Pippione, Donatella Boschi, Yu-Shin Ding, Marco Lucio Lolli
Synthesis of [18F]Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase
2019-01-01 Elena Martino, Stefano Sainas, Agnese C. Pippione, Donatella Boschi, Yu-Shin Ding, Marco L. Lolli.
Synthesis of [18F]Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase
2019-01-01 Elena Martino, Stefano Sainas, Agnese C. Pippione, Donatella Boschi, Yu- Shin Ding, Marco L. Lolli
Turning the light on with pyrazolo[1,5-A]pyridine: exploring it’s fluorescent properties for the design of new fluorosteric compounds
2023-01-01 Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Marta Giorgis, Bente Frølund, Marco Lucio Lolli
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
A new pro-apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor | 2021 | Sainas Sainas, Paola Circosta, Noemi Villella, Elena Martino, Agnese Chiara Pippione, Mohammad Houshmand, Marta Giorgis, Valentina Gaidano, Alessandro Cignetti, Caterina Peraldo Neia, Giovanna Chiorino, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli. | |
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent | 2024 | Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M.; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L.; Miggiano, Riccardo | |
Design and synthesis of a library of pyrazolo[1,5-a]pyridine fluorophores for developing new fluorescent probes | 2021 | Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Donatella Boschi, Bente Frølund, Marco Lucio Lolli | |
Design of new human Dihydroorotate Dehydrogenase inhibitors: amide bioisosterism in MEDS433 optimization | 2021 | Martino Elena, Villella Noemi, Vigato Chiara, Cerrina Matteo, Bersani Matteo, Giorgis Marta, Sainas Stefano, Boschi Donatella, Lolli Marco Lucio | |
Develop of new fluorescent probe to target hDHODH enzyme | 2022 | Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Agnese Chiara Pippione, Marta Giorgis, Donatella Boschi, Bente Frølund, Marco Lucio Lolli | |
Improving the fluorescent profile of pyrazolo [1,5-a]pyridine fluorophores for developing new fluorescent probes | 2022 | Elena Martino, Noemi Villella, Stefano Sainas, Francesco Bavo, Claudio Garino, Simona Mattiussi, Agnese Chiara Pippione, Marta Giorgis, Donatella Boschi, Bente Frølund, Marco Lucio Lolli. | |
Investigation of the central core of MEDS433: A Bioisosteric voyage into the Amide's Role | 2024 | Elena Martino, Stefano Sainas, Iole Manella, Marta Alberti, Marta Giorgis, Paola Circosta, Donatella Boschi and Marco Lucio Lolli | |
Investigation of the central core of MEDS433: A Bioisosteric voyage into the Amide's Role. | 2024 | Elena Martino, Stefano Sainas, Marta Alberti, Iole Mannella, Marta Giorgis, Paola Circosta, Donatella Boschi, Marco Lucio Lolli | |
Radiosynthesis of [18F]brequinar for in vivo PET imaging of hDHODH for potential studies of acute myeloid leukemia and cancers | 2024 | Sainas, Stefano; Banka, Vinay Kumar; Martino, Elena; Wang, Jiacheng; Lolli, Marco Lucio; Ding, Yu-Shin | |
Synthesis of [18F] Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase | 2019 | Elena Martino, Stefano Sainas, Agnese Chiara Pippione, Donatella Boschi, Yu-Shin Ding, Marco Lucio Lolli | |
Synthesis of [18F]Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase | 2019 | Elena Martino, Stefano Sainas, Agnese C. Pippione, Donatella Boschi, Yu-Shin Ding, Marco L. Lolli. | |
Synthesis of [18F]Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase | 2019 | Elena Martino, Stefano Sainas, Agnese C. Pippione, Donatella Boschi, Yu- Shin Ding, Marco L. Lolli | |
Turning the light on with pyrazolo[1,5-A]pyridine: exploring it’s fluorescent properties for the design of new fluorosteric compounds | 2023 | Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Marta Giorgis, Bente Frølund, Marco Lucio Lolli |