MARTINO, ELENA

MARTINO, ELENA  

SCIENZA E TECNOLOGIA DEL FARMACO  

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A new pro-apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor 2021 Sainas Sainas, Paola Circosta, Noemi Villella, Elena Martino, Agnese Chiara Pippione, Mohammad Houshmand, Marta Giorgis, Valentina Gaidano, Alessandro Cignetti, Caterina Peraldo Neia, Giovanna Chiorino, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli.
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent 2024 Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M.; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L.; Miggiano, Riccardo
Design and synthesis of a library of pyrazolo[1,5-a]pyridine fluorophores for developing new fluorescent probes 2021 Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Donatella Boschi, Bente Frølund, Marco Lucio Lolli
Design of new human Dihydroorotate Dehydrogenase inhibitors: amide bioisosterism in MEDS433 optimization 2021 Martino Elena, Villella Noemi, Vigato Chiara, Cerrina Matteo, Bersani Matteo, Giorgis Marta, Sainas Stefano, Boschi Donatella, Lolli Marco Lucio
Develop of new fluorescent probe to target hDHODH enzyme 2022 Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Agnese Chiara Pippione, Marta Giorgis, Donatella Boschi, Bente Frølund, Marco Lucio Lolli
Improving the fluorescent profile of pyrazolo [1,5-a]pyridine fluorophores for developing new fluorescent probes 2022 Elena Martino, Noemi Villella, Stefano Sainas, Francesco Bavo, Claudio Garino, Simona Mattiussi, Agnese Chiara Pippione, Marta Giorgis, Donatella Boschi, Bente Frølund, Marco Lucio Lolli.
Insight in Quinazoline-based HDAC Inhibitors as Anti-cancer Agents 2024 Martino, Elena; Thakur, Shruti; Kumar, Arun; Yadav, Ashok Kumar; Boschi, Donatella; Kumar, Deepak; Lolli, Marco
Investigation of the central core of MEDS433: A Bioisosteric voyage into the Amide's Role 2024 Elena Martino, Stefano Sainas, Iole Manella, Marta Alberti, Marta Giorgis, Paola Circosta, Donatella Boschi and Marco Lucio Lolli
Investigation of the central core of MEDS433: A Bioisosteric voyage into the Amide's Role. 2024 Elena Martino, Stefano Sainas, Marta Alberti, Iole Mannella, Marta Giorgis, Paola Circosta, Donatella Boschi, Marco Lucio Lolli
Radiosynthesis of [18F]brequinar for in vivo PET imaging of hDHODH for potential studies of acute myeloid leukemia and cancers 2024 Sainas, Stefano; Banka, Vinay Kumar; Martino, Elena; Wang, Jiacheng; Lolli, Marco Lucio; Ding, Yu-Shin
Synthesis of [18F] Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase 2019 Elena Martino, Stefano Sainas, Agnese Chiara Pippione, Donatella Boschi, Yu-Shin Ding, Marco Lucio Lolli
Synthesis of [18F]Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase 2019 Elena Martino, Stefano Sainas, Agnese C. Pippione, Donatella Boschi, Yu-Shin Ding, Marco L. Lolli.
Synthesis of [18F]Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase 2019 Elena Martino, Stefano Sainas, Agnese C. Pippione, Donatella Boschi, Yu- Shin Ding, Marco L. Lolli
Turning the light on with pyrazolo[1,5-A]pyridine: exploring it’s fluorescent properties for the design of new fluorosteric compounds 2023 Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Marta Giorgis, Bente Frølund, Marco Lucio Lolli