OLIARO BOSSO, Simonetta

OLIARO BOSSO, Simonetta  

SCIENZA E TECNOLOGIA DEL FARMACO  

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Titolo Data di pubblicazione Autore(i) File
4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase 2015 Ferrante, Terenzio; Barge, Alessandro; Albezzano, Claudia; Ballestrazzi Clara; Balliano, Gianni; Oliaro-Bosso, Simonetta
A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27) 2012 Layer Jacob V; Barnes Brett M; Yamasaki Yuji; Barbuch Robert; Li Lingtao; Taramino Silvia; Oliaro-Bosso Simonetta; Balliano Gianni; Bard Martin
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 2009 S. Oliaro-Bosso; S. Taramino; Y. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 2004 OLIARO-BOSSO S.; SCALDAFERRI M.; TARAMINO S.; F. VIOLA; G. BALLIANO
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 2005 Balliano G.; Oliaro-Bosso S.; Taramino S.; Viola F
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 2019 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi
Application of an in-house Bioisosteric Approach to the Design of Innovative Inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3) 2019 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro Bosso, Marco Lucio Lolli, Donatella Boschi
Characterization of C-4 demethylation complex of cholesterol biosynthesis 2012 Brozzu Andrea; Oliaro-Bosso Simonetta; Zonari Daniele; Viola Franca; Poirier Donald; Cunningham David; Herman Gail; Jokela Heili; Poutanen Matti; Balliano Gianni
Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job 2015 Ferrante, Terenzio; Remani, Elisa; Baratta, Erica; Poirier, Donald; Balliano, Gianni; Oliaro-Bosso, Simonetta
Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer 2016 Lolli, Marco; Cena, Clara; Giraudo, Alessandro; Marini, Elisabetta; Pippione, Agnese; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Sadiq, Maria; Pors, Klaus; Boschi, Donatella; Braga, Rudolpho; Andrade, Carolina.
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 2011 S. Taramino; B. Teske; S. Oliaro-Bosso; F. Viola; M. Bard; G. Balliano
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 2010 Silvia Taramino; Brian Teske; Simonetta Oliaro-Bosso; Franca Viola; Martin Bard; Gianni Balliano
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 2011 Claudia Meda; Simonetta Oliaro-Bosso; Marina Visentin; Carlo Cerato; Valmira Lena; Federico Bussolino; Gianni Balliano; Franca Viola; Enrico Giraudo
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 2007 S. Oliaro-Bosso; S. Taramino; I. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 2007 S. Oliaro-Bosso; S. Taramino; I. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 2012 Viola Franca; Balliano Gianni; Ruf Armin; Taramino Silvia; di Bartolo Giuseppe; Oliaro-Bosso Simonetta
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 2009 S. Taramino; M. Valachovic; S. Oliaro-Bosso; F. Viola; B. Teske; M. Bard; G. Balliano
Multiple-targeting ligands for AKR1C3 enzyme and androgen receptor to target prostate cancer 2021 Agnese Chiara Pippione, Zuhal Kilic-Kurt, Stefano Sainas, Iole Mannella, Barbara Rolando, Sandra Kovachka, Francesca Spyrakis, Annamaria Buschini, Serena Montalbano, Simonetta Oliaro Bosso, Marco Lolli, Donatella Boschi
Mutagenesi sito-specifica per lo studio di analogie strutturali tra squalene-opene ciclasi e ossidosqualene ciclasi. 2004 S. Oliaro-Bosso; M. Scaldaferri; F. Viola; G. Balliano
NEW HYDROXYAZOLES INHIBITORS OF AKR1C3 OBTAINED FROM NSAIDS BY SCAFFOLD HOPPING APPROACH AGAINST CASTRATE RESISTANT PROSTATE CANCER 2016 Boschi, Donatella; Pippione, Agnese Chiara; Giraudo, Alessandro; Carnovale, Irene Maria; Zorniotti, Sonia; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Marini, Elisabetta; Pors, Klaus; Festuccia, Claudio; Monache, Simona Delle; Zaffaroni, Nadia; Braga, Rodolpho Campos; Lucio Lolli, Marco