OLIARO BOSSO, Simonetta
OLIARO BOSSO, Simonetta
SCIENZA E TECNOLOGIA DEL FARMACO
4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase
2015-01-01 Ferrante, Terenzio; Barge, Alessandro; Albezzano, Claudia; Ballestrazzi Clara; Balliano, Gianni; Oliaro-Bosso, Simonetta
A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27)
2012-01-01 Layer Jacob V; Barnes Brett M; Yamasaki Yuji; Barbuch Robert; Li Lingtao; Taramino Silvia; Oliaro-Bosso Simonetta; Balliano Gianni; Bard Martin
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach
2009-01-01 S. Oliaro-Bosso; S. Taramino; Y. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach.
2004-01-01 OLIARO-BOSSO S.; SCALDAFERRI M.; TARAMINO S.; F. VIOLA; G. BALLIANO
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach.
2005-01-01 Balliano G.; Oliaro-Bosso S.; Taramino S.; Viola F
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3)
2019-01-01 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro Bosso, Marco Lucio Lolli, Donatella Boschi
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3)
2019-01-01 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi
Characterization of C-4 demethylation complex of cholesterol biosynthesis
2012-01-01 Brozzu Andrea; Oliaro-Bosso Simonetta; Zonari Daniele; Viola Franca; Poirier Donald; Cunningham David; Herman Gail; Jokela Heili; Poutanen Matti; Balliano Gianni
Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job
2015-01-01 Ferrante, Terenzio; Remani, Elisa; Baratta, Erica; Poirier, Donald; Balliano, Gianni; Oliaro-Bosso, Simonetta
Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer
2016-01-01 Lolli, Marco; Cena, Clara; Giraudo, Alessandro; Marini, Elisabetta; Pippione, Agnese; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Sadiq, Maria; Pors, Klaus; Boschi, Donatella; Braga, Rudolpho; Andrade, Carolina.
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals
2011-01-01 S. Taramino; B. Teske; S. Oliaro-Bosso; F. Viola; M. Bard; G. Balliano
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals
2010-01-01 Silvia Taramino; Brian Teske; Simonetta Oliaro-Bosso; Franca Viola; Martin Bard; Gianni Balliano
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo
2011-01-01 Claudia Meda; Simonetta Oliaro-Bosso; Marina Visentin; Carlo Cerato; Valmira Lena; Federico Bussolino; Gianni Balliano; Franca Viola; Enrico Giraudo
Effects of new hydroxyazoles inhibitors of AKR1C3 on vitality of prostate and colorectal cancer cell lines
2019-01-01 Valentina Boscaro, Donatella Boschi, Simonetta Oliaro-Bosso, Martina Daga, Marco Lolli, Agnese Chiara Pippione, Margherita Gallicchio
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis
2007-01-01 S. Oliaro-Bosso; S. Taramino; I. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis.
2007-01-01 S. Oliaro-Bosso; S. Taramino; I. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris
2012-01-01 Viola Franca; Balliano Gianni; Ruf Armin; Taramino Silvia; di Bartolo Giuseppe; Oliaro-Bosso Simonetta
HYDROXYLATED HETEROCYCLES AS BIOISOSTERES OF THE CARBOXYLIC FUNCTION: DESIGN OF NEW AKR1C3 INHIBITORS ACTIVE IN PROSTATE CANCER
2023-01-01 Agnese C. Pippione, Stefano Sainas, Chiara Vigato, Iole Mannella, Irene Castellino, Sandra Kovachka, Mariia Iakovleva, Barbara Rolando, Tomasz Wrobel, Osman A. Mirza, Karla Frydenvang, Francesca Spyrakis, Simonetta Oliaro-Bosso, Marco L. Lolli, Donatella Boschi
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex
2009-01-01 S. Taramino; M. Valachovic; S. Oliaro-Bosso; F. Viola; B. Teske; M. Bard; G. Balliano
Multiple-targeting ligands for AKR1C3 enzyme and androgen receptor to target prostate cancer
2021-01-01 Agnese Chiara Pippione, Zuhal Kilic-Kurt, Stefano Sainas, Iole Mannella, Barbara Rolando, Sandra Kovachka, Francesca Spyrakis, Annamaria Buschini, Serena Montalbano, Simonetta Oliaro Bosso, Marco Lolli, Donatella Boschi
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase | 2015 | Ferrante, Terenzio; Barge, Alessandro; Albezzano, Claudia; Ballestrazzi Clara; Balliano, Gianni; Oliaro-Bosso, Simonetta | |
| A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27) | 2012 | Layer Jacob V; Barnes Brett M; Yamasaki Yuji; Barbuch Robert; Li Lingtao; Taramino Silvia; Oliaro-Bosso Simonetta; Balliano Gianni; Bard Martin | |
| Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach | 2009 | S. Oliaro-Bosso; S. Taramino; Y. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano | |
| Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. | 2004 | OLIARO-BOSSO S.; SCALDAFERRI M.; TARAMINO S.; F. VIOLA; G. BALLIANO | |
| Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. | 2005 | Balliano G.; Oliaro-Bosso S.; Taramino S.; Viola F | |
| Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) | 2019 | Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro Bosso, Marco Lucio Lolli, Donatella Boschi | |
| Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) | 2019 | Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi | |
| Characterization of C-4 demethylation complex of cholesterol biosynthesis | 2012 | Brozzu Andrea; Oliaro-Bosso Simonetta; Zonari Daniele; Viola Franca; Poirier Donald; Cunningham David; Herman Gail; Jokela Heili; Poutanen Matti; Balliano Gianni | |
| Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job | 2015 | Ferrante, Terenzio; Remani, Elisa; Baratta, Erica; Poirier, Donald; Balliano, Gianni; Oliaro-Bosso, Simonetta | |
| Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer | 2016 | Lolli, Marco; Cena, Clara; Giraudo, Alessandro; Marini, Elisabetta; Pippione, Agnese; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Sadiq, Maria; Pors, Klaus; Boschi, Donatella; Braga, Rudolpho; Andrade, Carolina. | |
| Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals | 2011 | S. Taramino; B. Teske; S. Oliaro-Bosso; F. Viola; M. Bard; G. Balliano | |
| Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals | 2010 | Silvia Taramino; Brian Teske; Simonetta Oliaro-Bosso; Franca Viola; Martin Bard; Gianni Balliano | |
| Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo | 2011 | Claudia Meda; Simonetta Oliaro-Bosso; Marina Visentin; Carlo Cerato; Valmira Lena; Federico Bussolino; Gianni Balliano; Franca Viola; Enrico Giraudo | |
| Effects of new hydroxyazoles inhibitors of AKR1C3 on vitality of prostate and colorectal cancer cell lines | 2019 | Valentina Boscaro, Donatella Boschi, Simonetta Oliaro-Bosso, Martina Daga, Marco Lolli, Agnese Chiara Pippione, Margherita Gallicchio | |
| Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis | 2007 | S. Oliaro-Bosso; S. Taramino; I. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano | |
| Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. | 2007 | S. Oliaro-Bosso; S. Taramino; I. Ferrari; G. Ermondi; G. Caron; F. Viola; G. Balliano | |
| Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris | 2012 | Viola Franca; Balliano Gianni; Ruf Armin; Taramino Silvia; di Bartolo Giuseppe; Oliaro-Bosso Simonetta | |
| HYDROXYLATED HETEROCYCLES AS BIOISOSTERES OF THE CARBOXYLIC FUNCTION: DESIGN OF NEW AKR1C3 INHIBITORS ACTIVE IN PROSTATE CANCER | 2023 | Agnese C. Pippione, Stefano Sainas, Chiara Vigato, Iole Mannella, Irene Castellino, Sandra Kovachka, Mariia Iakovleva, Barbara Rolando, Tomasz Wrobel, Osman A. Mirza, Karla Frydenvang, Francesca Spyrakis, Simonetta Oliaro-Bosso, Marco L. Lolli, Donatella Boschi | |
| Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex | 2009 | S. Taramino; M. Valachovic; S. Oliaro-Bosso; F. Viola; B. Teske; M. Bard; G. Balliano | |
| Multiple-targeting ligands for AKR1C3 enzyme and androgen receptor to target prostate cancer | 2021 | Agnese Chiara Pippione, Zuhal Kilic-Kurt, Stefano Sainas, Iole Mannella, Barbara Rolando, Sandra Kovachka, Francesca Spyrakis, Annamaria Buschini, Serena Montalbano, Simonetta Oliaro Bosso, Marco Lolli, Donatella Boschi |