VIGNA, Elisa
VIGNA, Elisa
ONCOLOGIA
"Active" cancer immunotherapy by anti-Met antibody gene transfer
2008-01-01 Vigna E; Pacchiana G; Mazzone M; Chiriaco C; Fontani L; Basilico C; Pennacchietti S; Comoglio PM
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.
1992-01-01 HARTMANN G ;NALDINI L ;WEIDNER KM ;SACHS M ;VIGNA E ;COMOGLIO PM ;BIRCHMEIER W
A highly potent and specific MET therapeutic protein antagonist with both ligand-dependent and ligand-independent activity.
2013-01-01 Olwill SA;Joffroy C;Gille H;Vigna E;Matschiner G;Allersdorfer A;Lunde BM;Jaworski J;Burrows JF;Chiriaco C;Christian HJ;Hülsmeyer M;Trentmann S;Jensen K;Hohlbaum AM;Audoly L
A receptor-antibody hybrid hampering MET-driven metastatic spread
2021-01-01 Modica C.; Basilico C.; Chiriaco C.; Borrelli N.; Comoglio P.M.; Vigna E.
Anti-Differentiation Effect of Oncogenic Met Receptor in Terminally-Differentiated Myotubes
2015-01-01 Valentina Sala;Simona Gallo;Stefano Gatti;Elisa Vigna;Antonio Ponzetto;Tiziana Crepaldi
Anti-met fab-fc for the treatment of a tumor and/or metastasis
2019-01-01 VIGNA ELISA; BASILICO CRISTINA; TIZIANA CREPALDI; COMOGLIO PAOLO MARIA
Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products
2007-01-01 COMOGLIO Paolo Maria; VIGNA Elisa; GIORDANO Silvia
Antibody Fragments, Compositions And Uses Thereof - granted patent (USA)
2019-01-01 Elisa Vigna; Paolo Michieli; Paolo Maria Comoglio
Biological activation of pro-HGF (hepatocyte growth factor) by urokinase is controlled by a stoichiometric reaction.
1995-01-01 NALDINI L ;VIGNA E ;BARDELLI A ;FOLLENZI A ;GALIMI F ;COMOGLIO PM
Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib
2016-01-01 Sala, Valentina; Gallo, Simona; Gatti, Stefano; Medico, Enzo; Vigna, Elisa; Cantarella, Daniela; Fontani, Lara; Natale, Massimo; Cimino, James; Morello, Mara; Comoglio, Paolo Maria; Ponzetto, Antonio; Crepaldi, Tiziana
CD44v6 as innovative sarcoma target for CAR-redirected CIK cells
2018-01-01 Leuci, V.; Casucci, G.M.; Grignani, G.; Rotolo, R.; Rossotti, U.; Vigna, E.; Gammaitoni, L.; Mesiano, G.; Fiorino, E.; Donini, C.; Pisacane, A.; ambrosio, L.D.; Pignochino, Y.; Aglietta, M.; Bondanza, A.; Sangiolo, D.
Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters.
2005-01-01 Amendola M;Venneri MA;Biffi A;Vigna E;Naldini L
CSPG4-specific CAR.CIK lymphocytes as a novel therapy for the treatment of multiple soft tissue sarcoma histotypes
2020-01-01 Leuci, Valeria; Donini, Chiara; Grignani, Giovanni; Rotolo, Ramona; Mesiano, Giulia; Fiorino, Erika; Gammaitoni, Loretta; D'Ambrosio, Lorenzo; Merlini, Alessandra; Landoni, Elisa; Medico, Enzo; Capellero, Sonia; Giraudo, Lidia; Cattaneo, Giulia; Iaia, Ilenia; Pignochino, Ymera; Basiricò, Marco; Vigna, Elisa; Pisacane, Alberto; Fagioli, Franca; Ferrone, Soldano; Aglietta, Massimo; Gianpietro, Dotti; Sangiolo, Dario
Dual Constant Domain-Fab: A novel strategy to improve half-life and potency of a Met therapeutic antibody
2016-01-01 Cignetto, Simona; Modica, Chiara; Chiriaco, Cristina; Fontani, Lara; Milla, Paola; Michieli, Paolo; Comoglio, Paolo M.; Vigna, Elisa
Efficacy of CAR-T immunotherapy in MET overexpressing tumors not eligible for anti-MET targeted therapy
2022-01-01 Chiriaco, Cristina; Donini, Chiara; Cortese, Marco; Ughetto, Stefano; Modica, Chiara; Martinelli, Ilaria; Proment, Alessia; Vitali, Letizia; Fontani, Lara; Casucci, Monica; Comoglio, Paolo Maria; Giordano, Silvia; Sangiolo, Dario; Leuci, Valeria; Vigna, Elisa
Efficient Tet-dependent expression of human factor IX in vivo by a new self-regulating lentiviral vector.
2005-01-01 Vigna E;Amendola M;Benedicenti F;Simmons AD;Follenzi A;Naldini L
Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor
2021-01-01 Desole C.; Gallo S.; Vitacolonna A.; Vigna E.; Basilico C.; Montarolo F.; Zuppini F.; Casanova E.; Miggiano R.; Ferraris D.M.; Bertolotto A.; Comoglio P.M.; Crepaldi T.
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.
1992-01-01 NALDINI L ;TAMAGNONE L ;VIGNA E ;SACHS M ;HARTMANN G ;BIRCHMEIER W ;DAIKUHARA Y ;TSUBOUCHI H ;BLASI F ;COMOGLIO PM
Genetic Ablation of the MET Oncogene Defines a Crucial Role of the HGF/MET Axis in Cell-Autonomous Functions Driving Tumor Dissemination
2023-01-01 Chiara Modica; Marco Cortese; Francesca Bersani; Andrea Maria Lombardi; Francesca Napoli; Luisella Righi; Riccardo Taulli; Cristina Basilico; Elisa Vigna
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.
1991-01-01 NALDINI L ;VIGNA E ;NARSIMHAN RP ;GAUDINO G ;ZARNEGAR R ;MICHALOPOULOS GK ;COMOGLIO PM
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| "Active" cancer immunotherapy by anti-Met antibody gene transfer | 2008 | Vigna E; Pacchiana G; Mazzone M; Chiriaco C; Fontani L; Basilico C; Pennacchietti S; Comoglio PM | |
| A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. | 1992 | HARTMANN G ;NALDINI L ;WEIDNER KM ;SACHS M ;VIGNA E ;COMOGLIO PM ;BIRCHMEIER W | |
| A highly potent and specific MET therapeutic protein antagonist with both ligand-dependent and ligand-independent activity. | 2013 | Olwill SA;Joffroy C;Gille H;Vigna E;Matschiner G;Allersdorfer A;Lunde BM;Jaworski J;Burrows JF;Chiriaco C;Christian HJ;Hülsmeyer M;Trentmann S;Jensen K;Hohlbaum AM;Audoly L | |
| A receptor-antibody hybrid hampering MET-driven metastatic spread | 2021 | Modica C.; Basilico C.; Chiriaco C.; Borrelli N.; Comoglio P.M.; Vigna E. | |
| Anti-Differentiation Effect of Oncogenic Met Receptor in Terminally-Differentiated Myotubes | 2015 | Valentina Sala;Simona Gallo;Stefano Gatti;Elisa Vigna;Antonio Ponzetto;Tiziana Crepaldi | |
| Anti-met fab-fc for the treatment of a tumor and/or metastasis | 2019 | VIGNA ELISA; BASILICO CRISTINA; TIZIANA CREPALDI; COMOGLIO PAOLO MARIA | |
| Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products | 2007 | COMOGLIO Paolo Maria; VIGNA Elisa; GIORDANO Silvia | |
| Antibody Fragments, Compositions And Uses Thereof - granted patent (USA) | 2019 | Elisa Vigna; Paolo Michieli; Paolo Maria Comoglio | |
| Biological activation of pro-HGF (hepatocyte growth factor) by urokinase is controlled by a stoichiometric reaction. | 1995 | NALDINI L ;VIGNA E ;BARDELLI A ;FOLLENZI A ;GALIMI F ;COMOGLIO PM | |
| Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib | 2016 | Sala, Valentina; Gallo, Simona; Gatti, Stefano; Medico, Enzo; Vigna, Elisa; Cantarella, Daniela; Fontani, Lara; Natale, Massimo; Cimino, James; Morello, Mara; Comoglio, Paolo Maria; Ponzetto, Antonio; Crepaldi, Tiziana | |
| CD44v6 as innovative sarcoma target for CAR-redirected CIK cells | 2018 | Leuci, V.; Casucci, G.M.; Grignani, G.; Rotolo, R.; Rossotti, U.; Vigna, E.; Gammaitoni, L.; Mesiano, G.; Fiorino, E.; Donini, C.; Pisacane, A.; ambrosio, L.D.; Pignochino, Y.; Aglietta, M.; Bondanza, A.; Sangiolo, D. | |
| Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters. | 2005 | Amendola M;Venneri MA;Biffi A;Vigna E;Naldini L | |
| CSPG4-specific CAR.CIK lymphocytes as a novel therapy for the treatment of multiple soft tissue sarcoma histotypes | 2020 | Leuci, Valeria; Donini, Chiara; Grignani, Giovanni; Rotolo, Ramona; Mesiano, Giulia; Fiorino, Erika; Gammaitoni, Loretta; D'Ambrosio, Lorenzo; Merlini, Alessandra; Landoni, Elisa; Medico, Enzo; Capellero, Sonia; Giraudo, Lidia; Cattaneo, Giulia; Iaia, Ilenia; Pignochino, Ymera; Basiricò, Marco; Vigna, Elisa; Pisacane, Alberto; Fagioli, Franca; Ferrone, Soldano; Aglietta, Massimo; Gianpietro, Dotti; Sangiolo, Dario | |
| Dual Constant Domain-Fab: A novel strategy to improve half-life and potency of a Met therapeutic antibody | 2016 | Cignetto, Simona; Modica, Chiara; Chiriaco, Cristina; Fontani, Lara; Milla, Paola; Michieli, Paolo; Comoglio, Paolo M.; Vigna, Elisa | |
| Efficacy of CAR-T immunotherapy in MET overexpressing tumors not eligible for anti-MET targeted therapy | 2022 | Chiriaco, Cristina; Donini, Chiara; Cortese, Marco; Ughetto, Stefano; Modica, Chiara; Martinelli, Ilaria; Proment, Alessia; Vitali, Letizia; Fontani, Lara; Casucci, Monica; Comoglio, Paolo Maria; Giordano, Silvia; Sangiolo, Dario; Leuci, Valeria; Vigna, Elisa | |
| Efficient Tet-dependent expression of human factor IX in vivo by a new self-regulating lentiviral vector. | 2005 | Vigna E;Amendola M;Benedicenti F;Simmons AD;Follenzi A;Naldini L | |
| Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor | 2021 | Desole C.; Gallo S.; Vitacolonna A.; Vigna E.; Basilico C.; Montarolo F.; Zuppini F.; Casanova E.; Miggiano R.; Ferraris D.M.; Bertolotto A.; Comoglio P.M.; Crepaldi T. | |
| Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. | 1992 | NALDINI L ;TAMAGNONE L ;VIGNA E ;SACHS M ;HARTMANN G ;BIRCHMEIER W ;DAIKUHARA Y ;TSUBOUCHI H ;BLASI F ;COMOGLIO PM | |
| Genetic Ablation of the MET Oncogene Defines a Crucial Role of the HGF/MET Axis in Cell-Autonomous Functions Driving Tumor Dissemination | 2023 | Chiara Modica; Marco Cortese; Francesca Bersani; Andrea Maria Lombardi; Francesca Napoli; Luisella Righi; Riccardo Taulli; Cristina Basilico; Elisa Vigna | |
| Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. | 1991 | NALDINI L ;VIGNA E ;NARSIMHAN RP ;GAUDINO G ;ZARNEGAR R ;MICHALOPOULOS GK ;COMOGLIO PM |