ARENA, Sabrina
ARENA, Sabrina
ONCOLOGIA
213 Design, characterization and preclinical validation of a combinatorial CAR-based immunotherapy against colorectal cancer with HER2 amplification
2022-01-01 Cortese, Marco; Torchiaro, Erica; Leto, Simonetta; Petti, Consalvo; D'Andrea, Alice; Degree, Master; Invrea, Federica; Arena, Sabrina; Medico, Enzo
223P Artificial intelligence-based pathomics biomarker predict primary resistance to first-line treatment in metastatic colorectal cancers
2023-01-01 Mauri, G.; Giannini, V.; Nicoletti, G.; Lazzari, L.; Sartore Bianchi, A.; Marmorino, F.; Randon, G.; Nieva Munoz, M.; Saoudi Gonzalez, N.; Puccini, A.; Berrino, E.; Marchiò, C.; Di Como, M.; Aquilano, M.C.; Arena, S.; Torri, V.; Siena, S.; Bardelli, A.; Regge, D.; Marsoni, S.
A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin
2019-01-01 Arena, Sabrina; Corti, Giorgio; Durinikova, Erika; Montone, Monica; Reilly, Nicole M; Russo, Mariangela; Lorenzato, Annalisa; Arcella, Pamela; Lazzari, Luca; Rospo, Giuseppe; Pagani, Massimiliano; Cancelliere, Carlotta; Negrino, Carola; Isella, Claudio; Bartolini, Alice; Cassingena, Andrea; Amatu, Alessio; Mauri, Gianluca; Sartore-Bianchi, Andrea; Mittica, Gloria; Medico, Enzo; Marsoni, Silvia; Linnebacher, Michael; Abrignani, Sergio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto
Abstract 2148: MM-151 elicits broad and unique inhibition of cells harboring EGFR extracellular domain mutations — results of multiscale experiments with genome-edited cell lines
2016-01-01 Wang, Hongfang; Carey, Shawn P.; Burenkova, Olga; Tang, Jian; Gerami-Moayed, Nastaran; Arena, Sabrina; Bardelli, Alberto; Nering, Rachel; Kearns, Jeffrey D.
Abstract 2149: The anti-EGFR antibody mixture Sym004 overcomes acquired resistance to cetuximab in colorectal cancer
2016-01-01 Sanchez-Martin, Francisco J.; Dalmases, Alba; Bellosillo, Beatriz; Argiles, Guillem; Gelabert, Mariona; Cañadas, Israel; Vidal, Joana; Siravegna, Giulia; Arena, Sabrina; Koefoed, Klaus; Visa, Laura; Arpí, Oriol; Horak, Ivan D.; Iglesias, Mar; Stroh, Christopher; Kragh, Michael; Rovira, Ana; Albanell, Joan; Bardelli, Alberto; Tabernero, Josep; Montagut, Clara
Abstract 2913: Emergence of RAS or EGFR mutant clones affects duration of response to EGFR blockade in colorectal cancers
2017-01-01 Arena, Sabrina; Emburgh, Beth Van; Siravegna, Giulia; Lazzari, Luca; Crisafulli, Giovanni; Corti, Giorgio; Mussolin, Benedetta; Baldi, Federica; Buscarino, Michela; Bartolini, Alice; Valtorta, Emanuele; Vidal, Joana; Bellosillo, Beatriz; Germano, Giovanni; Pietrantonio, Filippo; Ponzetti, Agostino; Albanell, Joan; Siena, Salvatore; Sartore-Bianchi, Andrea; Nicolantonio, Federica Di; Montagut, Clara; Bardelli, Alberto
Abstract 3588: Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer
2015-01-01 Lazzari, Luca; Arena, Sabrina; Bellosillo, Beatriz; Siravegna, Giulia; Martínez, Alejandro; Cañadas, Israel; Ferruz, Noelia; Russo, Mariangela; Misale, Sandra; González, Iria; Iglesias, Mar; Gavilan, Elena; Corti, Giorgio; Hobor, Sebastijan; Crisafulli, Giovanni; Salido, Marta; Sánchez, Juan; Dalmases, Alba; Bellmunt, Joaquim; De Fabritiis, Gianni; Rovira, Ana; Di Nicolantonio, Federica; Albanell, Joan; Bardelli, Alberto; Montagut, Clara
Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification
2024-01-01 Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta M.; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo
Abstract 5900: Tolerance to colibactin correlates with response to chemotherapeutic agents in colorectal cancer
2023-01-01 Sogari, Alberto; Rovera, Emanuele; Reilly, Nicole Megan; Lamba, Simona; Russo, Mariangela; Lorenzato, Annalisa; Durinikova, Erika; Trusolino, Livio; Arena, Sabrina; Donalisio, Manuela; Nicolantonio, Federica Di; Lembo, David; Bardelli, Alberto
Abstract A120: Adaptive mutability of colorectal cancers in response to targeted therapies
2019-01-01 RUSSO, MARIANGELA; Crisafulli, Giovanni; Sogari, Alberto; Reilly, Nicole Megan; Arena, Sabrina; Lamba, Simona; Bartolini, Alice; Amodio, Vito; Magrì, Alessandro; Novara, Luca; Sarotto, Ivana; Nagel, Zachary; Piett, Cortt; Amatu, Alessio; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Bardelli, Alberto
Abstract B110: Heterogeneous genetic alterations emerge during acquired resistance to anti-EGFR therapy in colorectal cancer
2013-01-01 Arena, Sabrina; Misale, Sandra; Lamba, Simona; Siravegna, Giulia; Lallo, Alice; Hobor, Sebastijan; Russo, Mariangela; Buscarino, Michela; Sartore-Bianchi, Andrea; Bencardino, Katia; Amatu, Alessio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto
Abstract B33: The oligoclonal antibody MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancer cells harboring EGFR extracellular domain mutations
2016-01-01 Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex; Montagut, Clara; Nicolantonio, Federica Di; Nering, Rachel; Bardelli, Alberto
Abstract C94: Heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer are sensitive to concomitant inhibition of EGFR and MEK
2013-01-01 Misale, Sandra; Arena, Sabrina; Lamba, Simona; Siravegna, Giulia; Lallo, Alice; Hobor, Sebastijan; Russo, Mariangela; Buscarino, Michela; Sartore-Bianchi, Andrea; Bencardino, Katia; Amatu, Alessio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto
Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer
2019-01-01 Lazzari, Luca; Corti, Giorgio; Isella, Claudio; Montone, Monica; Arcella, Pamela; Zanella, Eugenia; Novara, Luca; Barbosa, Fabiane; Cassingena, Andrea; Cancelliere, Carlotta; Medico, Enzo; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Linnebacher, Michael; Bardelli, Alberto; Arena, Sabrina
Abstract LB058: A transcriptome-wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer
2023-01-01 Grasso, Gaia; Marriella, Elisa; Miotto, Martina; Buzo, Kristi; Reilly, Nicole M.; Andrei, Pietro; Vitiello, Pietro P.; Crisafulli, Giovanni; Arena, Sabrina; Rospo, Giuseppe; Corti, Giorgio; Lorenzato, Annalisa; Cancelliere, Carlotta; Barault, Ludovic; Gionfriddo, Giulia; Linnebacher, Michael; Russo, Mariangela; Nicolantonio, Federica Di; Bardelli, Alberto
Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer
2016-01-01 Van Emburgh, Beth O; Arena, Sabrina; Siravegna, Giulia; Lazzari, Luca; Crisafulli, Giovanni; Corti, Giorgio; Mussolin, Benedetta; Baldi, Federica; Buscarino, Michela; Bartolini, Alice; Valtorta, Emanuele; Vidal, Joana; Bellosillo, Beatriz; Germano, Giovanni; Pietrantonio, Filippo; Ponzetti, Agostino; Albanell, Joan; Siena, Salvatore; Sartore-Bianchi, Andrea; Di Nicolantonio, Federica; Montagut, Clara; Bardelli, Alberto
Active PI3K Pathway Causes an Invasive Phenotype Which Can Be Reversed or Promoted by Blocking the Pathway at Divergent Nodes.
2012-01-01 Wallin JJ;Guan J;Edgar KA;Zhou W;Francis R;Torres AC;Haverty PM;Eastham-Anderson J;Arena S;Bardelli A;Griffin S;Goodall JE;Grimshaw KM;Hoeflich KP;Torrance C;Belvin M;Friedman LS
Adaptive mutability of colorectal cancers in response to targeted therapies
2019-01-01 Russo M.; Crisafulli G.; Sogari A.; Reilly N.M.; Arena S.; Lamba S.; Bartolini A.; Amodio V.; Magri A.; Novara L.; Sarotto I.; Nagel Z.D.; Piett C.G.; Amatu A.; Sartore-Bianchi A.; Siena S.; Bertotti A.; Trusolino L.; Corigliano M.; Gherardi M.; Lagomarsino M.C.; Di Nicolantonio F.; Bardelli A.
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab.
2010-01-01 De Roock, W;* Jonker, Dj;* Di Nicolantonio, F; * Sartore-Bianchi, A; Tu, D; Siena, S; Lamba, S; Arena, S; Frattini, M; Piessevaux, H; Van Cutsem, E; O'Callaghan, Cj; Khambata-Ford, S; Zalcberg, Jr; Simes, J; Karapetis, Cs; Bardelli, A; Tejpar, S. (*co-first authorship)
Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer
2014-01-01 S. Misale;S. Arena;S. Lamba;G. Siravegna;A. Lallo;S. Hobor;M. Russo;M. Buscarino;L. Lazzari;A. Sartore-Bianchi;K. Bencardino;A. Amatu;C. Lauricella;E. Valtorta;S. Siena;F. Di Nicolantonio;A. Bardelli
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 213 Design, characterization and preclinical validation of a combinatorial CAR-based immunotherapy against colorectal cancer with HER2 amplification | 2022 | Cortese, Marco; Torchiaro, Erica; Leto, Simonetta; Petti, Consalvo; D'Andrea, Alice; Degree, Master; Invrea, Federica; Arena, Sabrina; Medico, Enzo | |
| 223P Artificial intelligence-based pathomics biomarker predict primary resistance to first-line treatment in metastatic colorectal cancers | 2023 | Mauri, G.; Giannini, V.; Nicoletti, G.; Lazzari, L.; Sartore Bianchi, A.; Marmorino, F.; Randon, G.; Nieva Munoz, M.; Saoudi Gonzalez, N.; Puccini, A.; Berrino, E.; Marchiò, C.; Di Como, M.; Aquilano, M.C.; Arena, S.; Torri, V.; Siena, S.; Bardelli, A.; Regge, D.; Marsoni, S. | |
| A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin | 2019 | Arena, Sabrina; Corti, Giorgio; Durinikova, Erika; Montone, Monica; Reilly, Nicole M; Russo, Mariangela; Lorenzato, Annalisa; Arcella, Pamela; Lazzari, Luca; Rospo, Giuseppe; Pagani, Massimiliano; Cancelliere, Carlotta; Negrino, Carola; Isella, Claudio; Bartolini, Alice; Cassingena, Andrea; Amatu, Alessio; Mauri, Gianluca; Sartore-Bianchi, Andrea; Mittica, Gloria; Medico, Enzo; Marsoni, Silvia; Linnebacher, Michael; Abrignani, Sergio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto | |
| Abstract 2148: MM-151 elicits broad and unique inhibition of cells harboring EGFR extracellular domain mutations — results of multiscale experiments with genome-edited cell lines | 2016 | Wang, Hongfang; Carey, Shawn P.; Burenkova, Olga; Tang, Jian; Gerami-Moayed, Nastaran; Arena, Sabrina; Bardelli, Alberto; Nering, Rachel; Kearns, Jeffrey D. | |
| Abstract 2149: The anti-EGFR antibody mixture Sym004 overcomes acquired resistance to cetuximab in colorectal cancer | 2016 | Sanchez-Martin, Francisco J.; Dalmases, Alba; Bellosillo, Beatriz; Argiles, Guillem; Gelabert, Mariona; Cañadas, Israel; Vidal, Joana; Siravegna, Giulia; Arena, Sabrina; Koefoed, Klaus; Visa, Laura; Arpí, Oriol; Horak, Ivan D.; Iglesias, Mar; Stroh, Christopher; Kragh, Michael; Rovira, Ana; Albanell, Joan; Bardelli, Alberto; Tabernero, Josep; Montagut, Clara | |
| Abstract 2913: Emergence of RAS or EGFR mutant clones affects duration of response to EGFR blockade in colorectal cancers | 2017 | Arena, Sabrina; Emburgh, Beth Van; Siravegna, Giulia; Lazzari, Luca; Crisafulli, Giovanni; Corti, Giorgio; Mussolin, Benedetta; Baldi, Federica; Buscarino, Michela; Bartolini, Alice; Valtorta, Emanuele; Vidal, Joana; Bellosillo, Beatriz; Germano, Giovanni; Pietrantonio, Filippo; Ponzetti, Agostino; Albanell, Joan; Siena, Salvatore; Sartore-Bianchi, Andrea; Nicolantonio, Federica Di; Montagut, Clara; Bardelli, Alberto | |
| Abstract 3588: Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer | 2015 | Lazzari, Luca; Arena, Sabrina; Bellosillo, Beatriz; Siravegna, Giulia; Martínez, Alejandro; Cañadas, Israel; Ferruz, Noelia; Russo, Mariangela; Misale, Sandra; González, Iria; Iglesias, Mar; Gavilan, Elena; Corti, Giorgio; Hobor, Sebastijan; Crisafulli, Giovanni; Salido, Marta; Sánchez, Juan; Dalmases, Alba; Bellmunt, Joaquim; De Fabritiis, Gianni; Rovira, Ana; Di Nicolantonio, Federica; Albanell, Joan; Bardelli, Alberto; Montagut, Clara | |
| Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification | 2024 | Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta M.; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo | |
| Abstract 5900: Tolerance to colibactin correlates with response to chemotherapeutic agents in colorectal cancer | 2023 | Sogari, Alberto; Rovera, Emanuele; Reilly, Nicole Megan; Lamba, Simona; Russo, Mariangela; Lorenzato, Annalisa; Durinikova, Erika; Trusolino, Livio; Arena, Sabrina; Donalisio, Manuela; Nicolantonio, Federica Di; Lembo, David; Bardelli, Alberto | |
| Abstract A120: Adaptive mutability of colorectal cancers in response to targeted therapies | 2019 | RUSSO, MARIANGELA; Crisafulli, Giovanni; Sogari, Alberto; Reilly, Nicole Megan; Arena, Sabrina; Lamba, Simona; Bartolini, Alice; Amodio, Vito; Magrì, Alessandro; Novara, Luca; Sarotto, Ivana; Nagel, Zachary; Piett, Cortt; Amatu, Alessio; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Bardelli, Alberto | |
| Abstract B110: Heterogeneous genetic alterations emerge during acquired resistance to anti-EGFR therapy in colorectal cancer | 2013 | Arena, Sabrina; Misale, Sandra; Lamba, Simona; Siravegna, Giulia; Lallo, Alice; Hobor, Sebastijan; Russo, Mariangela; Buscarino, Michela; Sartore-Bianchi, Andrea; Bencardino, Katia; Amatu, Alessio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto | |
| Abstract B33: The oligoclonal antibody MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancer cells harboring EGFR extracellular domain mutations | 2016 | Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex; Montagut, Clara; Nicolantonio, Federica Di; Nering, Rachel; Bardelli, Alberto | |
| Abstract C94: Heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer are sensitive to concomitant inhibition of EGFR and MEK | 2013 | Misale, Sandra; Arena, Sabrina; Lamba, Simona; Siravegna, Giulia; Lallo, Alice; Hobor, Sebastijan; Russo, Mariangela; Buscarino, Michela; Sartore-Bianchi, Andrea; Bencardino, Katia; Amatu, Alessio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto | |
| Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer | 2019 | Lazzari, Luca; Corti, Giorgio; Isella, Claudio; Montone, Monica; Arcella, Pamela; Zanella, Eugenia; Novara, Luca; Barbosa, Fabiane; Cassingena, Andrea; Cancelliere, Carlotta; Medico, Enzo; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Linnebacher, Michael; Bardelli, Alberto; Arena, Sabrina | |
| Abstract LB058: A transcriptome-wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer | 2023 | Grasso, Gaia; Marriella, Elisa; Miotto, Martina; Buzo, Kristi; Reilly, Nicole M.; Andrei, Pietro; Vitiello, Pietro P.; Crisafulli, Giovanni; Arena, Sabrina; Rospo, Giuseppe; Corti, Giorgio; Lorenzato, Annalisa; Cancelliere, Carlotta; Barault, Ludovic; Gionfriddo, Giulia; Linnebacher, Michael; Russo, Mariangela; Nicolantonio, Federica Di; Bardelli, Alberto | |
| Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer | 2016 | Van Emburgh, Beth O; Arena, Sabrina; Siravegna, Giulia; Lazzari, Luca; Crisafulli, Giovanni; Corti, Giorgio; Mussolin, Benedetta; Baldi, Federica; Buscarino, Michela; Bartolini, Alice; Valtorta, Emanuele; Vidal, Joana; Bellosillo, Beatriz; Germano, Giovanni; Pietrantonio, Filippo; Ponzetti, Agostino; Albanell, Joan; Siena, Salvatore; Sartore-Bianchi, Andrea; Di Nicolantonio, Federica; Montagut, Clara; Bardelli, Alberto | |
| Active PI3K Pathway Causes an Invasive Phenotype Which Can Be Reversed or Promoted by Blocking the Pathway at Divergent Nodes. | 2012 | Wallin JJ;Guan J;Edgar KA;Zhou W;Francis R;Torres AC;Haverty PM;Eastham-Anderson J;Arena S;Bardelli A;Griffin S;Goodall JE;Grimshaw KM;Hoeflich KP;Torrance C;Belvin M;Friedman LS | |
| Adaptive mutability of colorectal cancers in response to targeted therapies | 2019 | Russo M.; Crisafulli G.; Sogari A.; Reilly N.M.; Arena S.; Lamba S.; Bartolini A.; Amodio V.; Magri A.; Novara L.; Sarotto I.; Nagel Z.D.; Piett C.G.; Amatu A.; Sartore-Bianchi A.; Siena S.; Bertotti A.; Trusolino L.; Corigliano M.; Gherardi M.; Lagomarsino M.C.; Di Nicolantonio F.; Bardelli A. | |
| Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. | 2010 | De Roock, W;* Jonker, Dj;* Di Nicolantonio, F; * Sartore-Bianchi, A; Tu, D; Siena, S; Lamba, S; Arena, S; Frattini, M; Piessevaux, H; Van Cutsem, E; O'Callaghan, Cj; Khambata-Ford, S; Zalcberg, Jr; Simes, J; Karapetis, Cs; Bardelli, A; Tejpar, S. (*co-first authorship) | |
| Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer | 2014 | S. Misale;S. Arena;S. Lamba;G. Siravegna;A. Lallo;S. Hobor;M. Russo;M. Buscarino;L. Lazzari;A. Sartore-Bianchi;K. Bencardino;A. Amatu;C. Lauricella;E. Valtorta;S. Siena;F. Di Nicolantonio;A. Bardelli |