Nome |
# |
Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets, file e27ce42e-d58d-2581-e053-d805fe0acbaa
|
588
|
PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy, file e27ce42b-c899-2581-e053-d805fe0acbaa
|
348
|
Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells, file e27ce427-0e8f-2581-e053-d805fe0acbaa
|
267
|
Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance., file e27ce426-e3dd-2581-e053-d805fe0acbaa
|
252
|
Hypoxia as a driver of resistance to immunotherapy, file e27ce434-cd27-2581-e053-d805fe0acbaa
|
232
|
An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells, file e27ce427-135c-2581-e053-d805fe0acbaa
|
209
|
Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: A combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors, file e27ce428-b23e-2581-e053-d805fe0acbaa
|
209
|
The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells, file e27ce42b-bd7f-2581-e053-d805fe0acbaa
|
209
|
Bromodomain inhibition exerts its therapeutic potential in malignant pleural mesothelioma by promoting immunogenic cell death and changing the tumor immune-environment, file e27ce42c-95cd-2581-e053-d805fe0acbaa
|
207
|
ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma, file e27ce430-5e1a-2581-e053-d805fe0acbaa
|
198
|
Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells, file e27ce427-7e97-2581-e053-d805fe0acbaa
|
174
|
Potential diagnostic and prognostic role of micro-environment in malignant pleural mesothelioma, file e27ce42e-9574-2581-e053-d805fe0acbaa
|
165
|
Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5, file e27ce42e-d3fb-2581-e053-d805fe0acbaa
|
164
|
Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma, file e27ce427-01c1-2581-e053-d805fe0acbaa
|
163
|
Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells, file e27ce426-c1e6-2581-e053-d805fe0acbaa
|
140
|
Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance., file e27ce426-e3df-2581-e053-d805fe0acbaa
|
139
|
Effects of chrysotile exposure in human bronchial epithelial cells: Insights into the pathogenic mechanisms of asbestos-related diseases, file e27ce42a-6fc6-2581-e053-d805fe0acbaa
|
128
|
Cancer immunotherapy resistance based on immune checkpoints inhibitors: Targets, biomarkers, and remedies, file e27ce431-25b2-2581-e053-d805fe0acbaa
|
127
|
Cholesterol metabolism: At the cross road between cancer cells and immune environment, file e27ce431-b03a-2581-e053-d805fe0acbaa
|
123
|
Curcumin-loaded solid lipid nanoparticles bypass p-glycoprotein mediated doxorubicin resistance in triple negative breast cancer cells, file e27ce42f-cff3-2581-e053-d805fe0acbaa
|
122
|
Structure-Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands, file e27ce434-3b84-2581-e053-d805fe0acbaa
|
121
|
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer, file e27ce42d-6f16-2581-e053-d805fe0acbaa
|
117
|
Small nucleolar RNAs determine resistance to doxorubicin in human osteosarcoma, file e27ce430-5250-2581-e053-d805fe0acbaa
|
115
|
The Role of C/EBP-β LIP in Multidrug Resistance, file e27ce427-0e93-2581-e053-d805fe0acbaa
|
101
|
Liposomal Nitrooxy-Doxorubicin: One Step over Caelyx in Drug-Resistant Human Cancer Cells, file e27ce426-f58a-2581-e053-d805fe0acbaa
|
94
|
Mitochondrial delivery of phenol substructure triggers mitochondrial depolarization and apoptosis of cancer cells, file e27ce42c-f044-2581-e053-d805fe0acbaa
|
94
|
ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer, file e27ce42e-b0f3-2581-e053-d805fe0acbaa
|
94
|
HIF-1α is overexpressed in leukemic cells from TP53-disrupted patients and is a promising therapeutic target in chronic lymphocytic leukemia, file e27ce42e-ef9d-2581-e053-d805fe0acbaa
|
92
|
Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death, file e27ce430-524d-2581-e053-d805fe0acbaa
|
92
|
Temozolomide down-regulates P-glycoprotein in human blood-brain barrier cells by disrupting Wnt3-signalling., file e27ce426-fff7-2581-e053-d805fe0acbaa
|
88
|
Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance, file e27ce431-4653-2581-e053-d805fe0acbaa
|
87
|
Mrp1-collateral sensitizers as a novel therapeutic approach in resistant cancer therapy: An in vitro and in vivo study in lung resistant tumor, file e27ce430-524f-2581-e053-d805fe0acbaa
|
86
|
Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons, file e27ce430-f4d6-2581-e053-d805fe0acbaa
|
84
|
New tetrahydroisoquinoline derivatives overcome pgp activity in brain-blood barrier and glioblastoma multiforme in vitro, file e27ce42c-d292-2581-e053-d805fe0acbaa
|
81
|
P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors, file e27ce42a-ca7f-2581-e053-d805fe0acbaa
|
80
|
Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R), file e27ce430-5e17-2581-e053-d805fe0acbaa
|
79
|
Mitochondria-Targeted Doxorubicin: A New Therapeutic Strategy against Doxorubicin-Resistant Osteosarcoma, file e27ce42a-6983-2581-e053-d805fe0acbaa
|
77
|
Insights in the chemical components of liposomes responsible for P-glycoprotein inhibition., file e27ce426-fffc-2581-e053-d805fe0acbaa
|
76
|
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma, file e27ce433-72ec-2581-e053-d805fe0acbaa
|
75
|
HIF-1α is overexpressed in leukemic cells from TP53-disrupted patients and is a promising therapeutic target in chronic lymphocytic leukemia, file e27ce430-5244-2581-e053-d805fe0acbaa
|
66
|
IL17A Depletion Affects the Metabolism of Macrophages Treated with Gemcitabine, file e27ce432-2881-2581-e053-d805fe0acbaa
|
64
|
Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway, file e27ce42a-321f-2581-e053-d805fe0acbaa
|
63
|
Targeting mitochondrial oncometabolites: A new approach to overcome drug resistance in cancer, file e27ce432-400e-2581-e053-d805fe0acbaa
|
59
|
Targeting hif-1α regulatory pathways as a strategy to hamper tumor-microenvironment interactions in cll, file e27ce432-7ca5-2581-e053-d805fe0acbaa
|
59
|
Endothelial heme dynamics drive cancer cell metabolism by shaping the tumor microenvironment, file e27ce434-10e6-2581-e053-d805fe0acbaa
|
59
|
Two repeated low doses of doxorubicin are more effective than one single high dose against tumors overexpressing P-glycoprotein, file e27ce427-0e91-2581-e053-d805fe0acbaa
|
58
|
Ï-3 long chain polyunsaturated fatty acids as sensitizing agents and multidrug resistance revertants in cancer therapy, file e27ce42c-47ec-2581-e053-d805fe0acbaa
|
48
|
Zoledronic Acid Restores Doxorubicin Chemosensitivity
and Immunogenic Cell Death in Multidrug-Resistant
Human Cancer Cells, file e27ce426-e647-2581-e053-d805fe0acbaa
|
47
|
Loss of C/EBP-β LIP drives cisplatin resistance in malignant pleural mesothelioma, file e27ce42c-ef0d-2581-e053-d805fe0acbaa
|
46
|
Endothelial Cells Promote Osteogenesis by Establishing a Functional and Metabolic Coupling With Human Mesenchymal Stem Cells, file e27ce433-dfb2-2581-e053-d805fe0acbaa
|
43
|
Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: A combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors, file e27ce428-b23d-2581-e053-d805fe0acbaa
|
42
|
Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma, file e27ce432-dd86-2581-e053-d805fe0acbaa
|
40
|
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma, file e27ce434-bfe8-2581-e053-d805fe0acbaa
|
40
|
Regulation of HIF-1α in TP53 Disrupted Chronic Lymphocytic Leukemia Cells and Its Potential Role as a Therapeutic Target, file e27ce42e-24b0-2581-e053-d805fe0acbaa
|
39
|
Targeted Self-Emulsifying Drug Delivery Systems to Restore Docetaxel Sensitivity in Resistant Tumors, file e27ce434-b37f-2581-e053-d805fe0acbaa
|
39
|
Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts, file e27ce42e-af48-2581-e053-d805fe0acbaa
|
34
|
Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer, file 4633b8e9-c249-47ff-bdf1-56a6ad4a863b
|
33
|
Temozolomide down-regulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/GSK3/β-catenin pathway, file e27ce426-fff9-2581-e053-d805fe0acbaa
|
33
|
Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition., file e27ce426-f662-2581-e053-d805fe0acbaa
|
29
|
Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1, file e27ce42a-b8e0-2581-e053-d805fe0acbaa
|
29
|
Potential diagnostic and prognostic role of micro-environment in malignant pleural mesothelioma, file e27ce42e-85f8-2581-e053-d805fe0acbaa
|
28
|
The cross-talk between canonical and non-canonical Wnt-dependent
pathways regulates P-glycoprotein expression in human blood-brain barrier cells., file e27ce426-f604-2581-e053-d805fe0acbaa
|
26
|
Strategies to Overcome Resistance to Immune-Based Therapies in Osteosarcoma, file 266c22c8-4cf4-4132-83e2-aeb30738158d
|
25
|
Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells, file e27ce426-c24d-2581-e053-d805fe0acbaa
|
25
|
Multifunctional thiosemicarbazones targeting sigma receptors: in vitro and in vivo antitumor activities in pancreatic cancer models, file e27ce434-10e4-2581-e053-d805fe0acbaa
|
25
|
Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: A combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors, file e27ce428-b815-2581-e053-d805fe0acbaa
|
24
|
Cholesterol metabolism: At the cross road between cancer cells and immune environment, file e27ce431-2d61-2581-e053-d805fe0acbaa
|
24
|
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors, file e27ce433-469a-2581-e053-d805fe0acbaa
|
22
|
The role of extracellular vesicles in the transfer of drug resistance competences to cancer cells, file e27ce435-8f2c-2581-e053-d805fe0acbaa
|
22
|
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors, file e27ce42c-ef0f-2581-e053-d805fe0acbaa
|
20
|
Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein-Mediated Resistance to Temozolomide in Glioblastoma, file e27ce42d-7691-2581-e053-d805fe0acbaa
|
20
|
Electronic Coupling in 1,2,3-Triazole Bridged Ferrocenes and Its Impact on Reactive Oxygen Species Generation and Deleterious Activity in Cancer Cells, file e27ce435-a927-2581-e053-d805fe0acbaa
|
16
|
Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma, file e27ce42e-1c89-2581-e053-d805fe0acbaa
|
15
|
Long-Chain Acyl Coenzyme A Dehydrogenase, a Key Player in Metabolic Rewiring/Invasiveness in Experimental Tumors and Human Mesothelioma Cell Lines, file 34984ba2-bf1a-4d9d-8451-8ee380efcf90
|
14
|
Multifunctional thiosemicarbazones targeting sigma receptors: in vitro and in vivo antitumor activities in pancreatic cancer models, file e27ce434-3b88-2581-e053-d805fe0acbaa
|
14
|
mTORC2 Is Activated under Hypoxia and Could Support Chronic Myeloid Leukemia Stem Cells, file 8017d10f-3b03-4dec-bf4e-aacfc7c50603
|
12
|
Ï-3 long chain polyunsaturated fatty acids as sensitizing agents and multidrug resistance revertants in cancer therapy, file e27ce42c-a90f-2581-e053-d805fe0acbaa
|
10
|
Immune dysfunctions affecting bone marrow Vγ9Vδ2 T cells in multiple myeloma: Role of immune checkpoints and disease status, file 198819b3-8c00-465b-8a3e-8935cefc4fb0
|
9
|
Bromodomain inhibition exerts its therapeutic potential in malignant pleural mesothelioma by promoting immunogenic cell death and changing the tumor immune-environment, file e27ce42c-8aea-2581-e053-d805fe0acbaa
|
8
|
The multiple combination of Paclitaxel, Ramucirumab and Elacridar reverses the paclitaxel-mediated resistance in gastric cancer cell lines, file 8245f947-b847-4a68-8cbe-3654a453fa3e
|
7
|
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors, file e27ce42c-a984-2581-e053-d805fe0acbaa
|
7
|
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma, file e27ce42e-af46-2581-e053-d805fe0acbaa
|
6
|
Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein, file 57b43d5d-ce0a-4dd8-8465-0b7ba33c5dc2
|
5
|
Loss of C/EBP-β LIP drives cisplatin resistance in malignant pleural mesothelioma, file e27ce42c-f345-2581-e053-d805fe0acbaa
|
5
|
Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma, file e27ce42e-0506-2581-e053-d805fe0acbaa
|
5
|
Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5, file e27ce42e-99a1-2581-e053-d805fe0acbaa
|
5
|
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma, file e27ce432-55c5-2581-e053-d805fe0acbaa
|
5
|
Autocrine 17-β-estradiol/estrogen receptor-α loop determines the response to immune-checkpoint inhibitors in non-small cell lung cancer, file 4fd1d643-3fe1-48cc-9a70-14974c325626
|
4
|
The role of Extracellular Vesicles in glycolytic and lipid metabolic reprogramming of cancer cells: Consequences for drug resistance, file c7056d9a-fc89-447c-b865-5021aef8cd8d
|
4
|
Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance., file e27ce426-e3e0-2581-e053-d805fe0acbaa
|
3
|
Liposomal Nitrooxy-Doxorubicin: One Step over Caelyx in Drug-Resistant Human Cancer Cells, file e27ce426-f589-2581-e053-d805fe0acbaa
|
3
|
Editorial: Novel therapeutic approaches to target drug resistant tumors, file 176faa64-27c5-4abb-b187-b18aeefc75cf
|
2
|
Pleiotropic Effects of Cardioactive Glycosides., file e27ce426-ca97-2581-e053-d805fe0acbaa
|
2
|
Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein-Mediated Resistance to Temozolomide in Glioblastoma, file e27ce42d-6f15-2581-e053-d805fe0acbaa
|
2
|
Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts, file e27ce42e-a490-2581-e053-d805fe0acbaa
|
2
|
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors, file e27ce432-5653-2581-e053-d805fe0acbaa
|
2
|
Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells, file 3d48f008-ded1-48bc-9f2a-15704caa3aa9
|
1
|
4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells, file 4eb75aeb-a5b3-4a36-be79-e159e301f10c
|
1
|
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells, file e27ce426-cac0-2581-e053-d805fe0acbaa
|
1
|
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells, file e27ce426-cac1-2581-e053-d805fe0acbaa
|
1
|
Totale |
7.299 |