KOPECKA, Joanna
 Distribuzione geografica
Continente #
NA - Nord America 5.660
EU - Europa 3.242
AS - Asia 2.733
AF - Africa 74
SA - Sud America 51
OC - Oceania 34
Continente sconosciuto - Info sul continente non disponibili 8
Totale 11.802
Nazione #
US - Stati Uniti d'America 5.507
CN - Cina 1.903
IT - Italia 995
SE - Svezia 391
IE - Irlanda 355
AT - Austria 251
FR - Francia 233
DE - Germania 214
UA - Ucraina 156
JP - Giappone 135
FI - Finlandia 119
GB - Regno Unito 118
HK - Hong Kong 114
IN - India 105
PL - Polonia 101
VN - Vietnam 97
KR - Corea 85
CA - Canada 79
DK - Danimarca 73
MX - Messico 73
TW - Taiwan 65
SG - Singapore 64
TR - Turchia 43
RU - Federazione Russa 40
BE - Belgio 33
NL - Olanda 33
SN - Senegal 33
AU - Australia 30
ES - Italia 29
IR - Iran 23
BR - Brasile 20
TH - Thailandia 19
GR - Grecia 18
RO - Romania 18
CH - Svizzera 17
ID - Indonesia 17
MY - Malesia 14
CO - Colombia 13
ZA - Sudafrica 12
NO - Norvegia 11
EG - Egitto 9
IL - Israele 8
AR - Argentina 7
MO - Macao, regione amministrativa speciale della Cina 7
PT - Portogallo 7
AM - Armenia 6
BY - Bielorussia 6
EU - Europa 6
PE - Perù 6
AE - Emirati Arabi Uniti 5
CZ - Repubblica Ceca 5
HU - Ungheria 5
TN - Tunisia 5
MU - Mauritius 4
NZ - Nuova Zelanda 4
PH - Filippine 4
SA - Arabia Saudita 4
SI - Slovenia 4
BG - Bulgaria 3
DZ - Algeria 3
EC - Ecuador 3
IQ - Iraq 3
NG - Nigeria 3
SK - Slovacchia (Repubblica Slovacca) 3
UZ - Uzbekistan 3
BA - Bosnia-Erzegovina 2
CL - Cile 2
JO - Giordania 2
LB - Libano 2
PK - Pakistan 2
SD - Sudan 2
A1 - Anonimo 1
AP - ???statistics.table.value.countryCode.AP??? 1
AZ - Azerbaigian 1
HR - Croazia 1
LU - Lussemburgo 1
MA - Marocco 1
MM - Myanmar 1
MW - Malawi 1
PR - Porto Rico 1
PS - Palestinian Territory 1
SC - Seychelles 1
Totale 11.802
Città #
Chandler 649
Fairfield 489
Beijing 439
Houston 366
Dublin 353
Ashburn 352
Torino 326
Ann Arbor 314
Woodbridge 259
Vienna 232
Wilmington 216
Seattle 183
Cambridge 175
Shanghai 153
Nyköping 144
Dearborn 135
Guangzhou 126
Redwood City 125
Turin 110
Pisa 108
Villeurbanne 105
Medford 103
Princeton 98
Nanjing 81
New York 81
Hangzhou 71
Jacksonville 70
Warsaw 65
Dong Ket 59
Wuhan 59
Fremont 58
Taipei 43
Changsha 42
Central 39
San Diego 39
Boston 36
Tokyo 36
Shenyang 35
Milan 34
Hefei 31
Toronto 29
Boardman 27
Xian 27
Chengdu 26
Rome 25
Chongqing 24
Seoul 24
Tianjin 24
Zhengzhou 24
Istanbul 23
Jinan 22
Hebei 21
London 21
Phoenix 21
Fuzhou 19
Helsinki 19
Los Angeles 19
San Mateo 19
Brussels 18
Mountain View 18
Buffalo 17
Central District 16
Norwalk 16
Changchun 15
Chennai 15
Pune 15
San Giuliano Milanese 15
Upper Marlboro 15
Washington 15
Chicago 14
Florence 14
Singapore 14
Kunming 13
Paris 13
Shenzhen 13
Birmingham 12
Ottawa 12
Falls Church 11
Guiyang 11
Nanchang 11
Siena 11
Silver Spring 11
Athens 10
Hong Kong 10
Jakarta 10
Moscow 10
Piemonte 10
Xiamen 10
Bari 9
Detroit 9
Harbin 9
Hyderabad 9
Mexico 9
Qingdao 9
Bangkok 8
Leawood 8
Nanning 8
Osaka 8
San Jose 8
Adelaide 7
Totale 7.349
Nome #
Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets 1.383
Hypoxia as a driver of resistance to immunotherapy 468
Bromodomain inhibition exerts its therapeutic potential in malignant pleural mesothelioma by promoting immunogenic cell death and changing the tumor immune-environment 451
Temozolomide down-regulates P-glycoprotein in human blood-brain barrier cells by disrupting Wnt3-signalling. 290
REGULATION OF HIF-1 alpha IN TP53 DISRUPTED CHRONIC LYMPHOCYTIC LEUKEMIA CELLS AND ITS POTENTIAL ROLE AS A THERAPEUTIC TARGET 276
Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts 264
Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance. 259
Cholesterol metabolism: At the cross road between cancer cells and immune environment 259
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors 246
PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy 242
The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells 241
Potential diagnostic and prognostic role of micro-environment in malignant pleural mesothelioma 238
ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma 226
Loss of C/EBP-β LIP drives cisplatin resistance in malignant pleural mesothelioma 225
Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 210
An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells 209
Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R) 190
Insights in the chemical components of liposomes responsible for P-glycoprotein inhibition. 188
Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells 173
Liposomal Nitrooxy-Doxorubicin: One Step over Caelyx in Drug-Resistant Human Cancer Cells 166
Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: A combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors 162
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer 161
Small nucleolar RNAs determine resistance to doxorubicin in human osteosarcoma 154
Effects of chrysotile exposure in human bronchial epithelial cells: Insights into the pathogenic mechanisms of asbestos-related diseases 152
Zoledronic Acid Restores Doxorubicin Chemosensitivity and Immunogenic Cell Death in Multidrug-Resistant Human Cancer Cells 151
Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway 151
The cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells. 137
Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma 137
Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells 128
HIF-1α is overexpressed in leukemic cells from TP53-disrupted patients and is a promising therapeutic target in chronic lymphocytic leukemia 128
Curcumin-loaded solid lipid nanoparticles bypass p-glycoprotein mediated doxorubicin resistance in triple negative breast cancer cells 128
ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer 126
Temozolomide down-regulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/GSK3/β-catenin pathway 118
Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells 115
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma 107
Mitochondria-Targeted Doxorubicin: A New Therapeutic Strategy against Doxorubicin-Resistant Osteosarcoma 104
P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors 102
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells 101
Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance 101
New tetrahydroisoquinoline derivatives overcome pgp activity in brain-blood barrier and glioblastoma multiforme in vitro 101
Cancer immunotherapy resistance based on immune checkpoints inhibitors: Targets, biomarkers, and remedies 97
Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition. 95
Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma 94
Mitochondrial delivery of phenol substructure triggers mitochondrial depolarization and apoptosis of cancer cells 93
Regulation of HIF-1α in TP53 Disrupted Chronic Lymphocytic Leukemia Cells and Its Potential Role as a Therapeutic Target 93
Cardiac glycosides as new modulators of cholesterol metabolism 87
Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells 86
Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death 84
Endothelial Cells Promote Osteogenesis by Establishing a Functional and Metabolic Coupling With Human Mesenchymal Stem Cells 83
Pleiotropic Effects of Cardioactive Glycosides. 82
Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons 77
Digoxin and ouabain induce the efflux of cholesterol via LXR signalling and the synthesis of ATP in cardiomyocytes. 76
IL17A Depletion Affects the Metabolism of Macrophages Treated with Gemcitabine 76
Nitrooxy-doxorubicin: A New Weapon Against Multidrug Resistance. 73
HIF-1 alpha Upregulation in TP53 Disrupted Chronic Lymphocytic Leukemia Cells and Its Potential Role As a Therapeutic Target 72
ω-3 long chain polyunsaturated fatty acids as sensitizing agents and multidrug resistance revertants in cancer therapy 70
Mechanisms of Vgamma9Vdelta2 T cell activation by soluble metabolites generated by the mevalonate pathway. 70
The Hypoxia-Inducible Factor-1 alpha Is Constitutively Upregulated in TP53 Disrupted CLL Cells: A Potential Target to Overcome Fludarabine Resistance 69
Two repeated low doses of doxorubicin are more effective than one single high dose against tumors overexpressing P-glycoprotein 67
Temozolomide epigenetically down-regulates Wnt3a-dependent signaling and P- glycoprotein in glioblastoma stem cells 65
Digoxin and oubain increase the synthesis of cholesterol in human liver cells 65
Mitochondrial metabolism: Inducer or therapeutic target in tumor immune-resistance? 65
Liposomal doxorubicin reverses drug-resistance by inhibiting P-glycoprotein in human cancer cells 64
Cardiac glycosides modulate cholesterol metabolism via SREBP-2 and LXR activation 64
Regulation of HIF-1α in TP53 disrupted chronic lymphocytic leukemia cells and its potential role as a therapeutic target 64
Cardioactive glycosides induce the efflux of cholesterol by upregulating ABCA1 62
Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein-Mediated Resistance to Temozolomide in Glioblastoma 61
Mrp1-collateral sensitizers as a novel therapeutic approach in resistant cancer therapy: An in vitro and in vivo study in lung resistant tumor 60
The Role of C/EBP-β LIP in Multidrug Resistance 59
Targeting hif-1α regulatory pathways as a strategy to hamper tumor-microenvironment interactions in cll 58
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells 57
REGULATION OF HIF-1 IN TP53 DISRUPTED CLL CELLS AND ITS INHIBITION AS A STRATEGY TO OVERCOME FLUDARABINE RESISTANCE 56
Endothelial heme dynamics drive cancer cell metabolism by shaping the tumor microenvironment 55
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma 55
Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1 54
Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein 53
Modulation of doxorubicin resistance by the glucose 6-phosphate dehydrogenase activity 51
Targeting mitochondrial oncometabolites: A new approach to overcome drug resistance in cancer 47
REGULATION OF HIF-1 alpha IN TP53 DISRUPTED CHRONIC LYMPHOCYTIC LEUKEMIA CELLS AND ITS POTENTIAL ROLE AS A THERAPEUTIC TARGET 46
Liposome-encapsulated doxorubicin reverses drug resistance by inhibiting P-glycoprotein in human cancer cells. 45
The “LDL-masked doxorubicin”: an effective strategy for drug delivery across hypoxic blood brain barrier 44
Click ferrocenyl-erlotinib conjugates active against erlotinib-resistant non-small cell lung cancer cells in vitro 44
Regulation of HIF-1α in TP53 disrupted chronic lymphocytic leukemia cells and its potential role as a therapeutic target 43
Modulation of doxorubicin resistance by the glucose 6-phosphate dehydrogenase activity 42
Pleiotropic effects of liposomal nanoparticles on ABCB1 in cancer cells 40
Targeting mevalonate pathway down-regulates ABCB1, reversing chemoresistance and immunoresistance in human cancer cells. 37
Structure-Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands 37
Modulation of doxorubicin resistance by the glucose 6-phosphate dehydrogenase activity 34
Modulation of doxorubicin resistance by the glucose 6-phosphate dehydrogenase activity 34
Nanoparticle- and liposome-carried drugs: new strategies for active targeting and drug delivery across blood-brain barrier. 31
Immune dysfunctions affecting bone marrow Vγ9Vδ2 T cells in multiple myeloma: Role of immune checkpoints and disease status 30
The role of extracellular vesicles in the transfer of drug resistance competences to cancer cells 29
Multifunctional thiosemicarbazones targeting sigma receptors: in vitro and in vivo antitumor activities in pancreatic cancer models 28
mTORC2 Is Activated under Hypoxia and Could Support Chronic Myeloid Leukemia Stem Cells 24
Electronic Coupling in 1,2,3-Triazole Bridged Ferrocenes and Its Impact on Reactive Oxygen Species Generation and Deleterious Activity in Cancer Cells 22
Autocrine 17-β-estradiol/estrogen receptor-α loop determines the response to immune-checkpoint inhibitors in non-small cell lung cancer 21
Malignant mesothelioma 21
Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer 19
Targeted Self-Emulsifying Drug Delivery Systems to Restore Docetaxel Sensitivity in Resistant Tumors 14
The role of Extracellular Vesicles in glycolytic and lipid metabolic reprogramming of cancer cells: Consequences for drug resistance 4
Totale 12.116
Categoria #
all - tutte 29.473
article - articoli 0
book - libri 0
conference - conferenze 4.315
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.788


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019479 0 0 0 0 0 0 0 0 0 139 221 119
2019/20201.529 52 45 68 155 107 236 157 134 158 174 125 118
2020/20212.161 106 232 144 165 211 156 199 172 178 187 176 235
2021/20222.132 121 103 111 218 89 118 159 148 139 190 426 310
2022/20232.335 217 181 84 184 189 503 204 158 255 83 134 143
2023/20241.727 200 216 133 150 143 335 166 170 56 158 0 0
Totale 12.134