GASTALDI, SIMONE
GASTALDI, SIMONE
SCIENZA E TECNOLOGIA DEL FARMACO
Covalent NLRP3 inhibitors: design strategies, synthesis and pharmacological characterization
2018-01-01 Gastaldi S., Introvigne M.L., Marino M., Marini E., Bertinaria M. Giorgis M.
Design and synthesis of encorafenib-based BRAF-V600E degraders
2022-01-01 Federica Blua, Marco Marino, Simone Gastaldi, Federica Maione, Eleonora Gianquinto, Federica Di Nicolantonio, Massimo Bertinaria
Design and synthesis of INF195, a new NLRP3 Inflammasome Inhibitor with ex vivo cardioprotective effect
2024-01-01 Francesca Boccato, Simone Gastaldi, Magalì Giordano, Elisabetta Marini, Francesca Spyrakis, Pasquale Pagliaro, Claudia Penna, Massimo Bertinaria
EVALUATION OF THE ANTIPYROPTOTIC ACTIVITY OF NEW INFLAMMASOME INHIBITORS
2021-01-01 Boscaro Valentina, Gastaldi Simone, Bertinaria Massimo, Gallicchio Margherita
In silico study of NLRP3: towards selective inhibition with small molecules
2019-01-01 Alejandro Gómez García, Simone Gastaldi, Giulia Fumero, Massimo Bertinaria, José Luis Medina Franco
In the search for new NLRP3 inhibitors: chemical modulation of the 1-(piperidin-4-yl)-1,3-dihydro-2 Hbenzo[d]imidazole-2-one scaffold
2021-01-01 Simone Gastaldi, Valentina Boscaro, Eleonora Gianquinto, Christina F. Sandall, Marta Giorgis, Elisabetta Marini, Federica Blua, Margherita Gallicchio, Francesca Spyrakis, Justin A. MacDonald, Massimo Bertinaria
Inhibition of NLRP3 ATPase activity: a new strategy to fight chronic inflammatory diseases
2019-01-01 Simone Gastaldi, Federica Blua, Marta Giorgis, Elisabetta Marini, Massimo Bertinaria
NEW NON-COVALENT INHIBITORS OF NLRP3 INFLAMMASOME ATPASE ACTIVITY
2019-01-01 Gastaldi, S; Marino, M.; Giorgis, M.; Marini, E.; Boscaro, V.; Gallicchio, M.; Bertinaria, M.
Pharmacological characterization of new NLRP3 inflammasome inhibitors.
2019-01-01 Valentina Boscaro, Simone Gastaldi, Marco Marino, Marta Giorgis, Elisabetta Marini, Massimo Bertinaria, Margherita Gallicchio
Targeting NLRP3 inflammasome: development of new covalent and non-covalent inhibitors of ATPase activity
2019-01-01 Elisabetta Marini, Simone Gastaldi, Marta Giorgis, Marco Marino, Valentina Boscaro, Margherita Gallicchio, Massimo Bertinaria
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Covalent NLRP3 inhibitors: design strategies, synthesis and pharmacological characterization | 2018 | Gastaldi S., Introvigne M.L., Marino M., Marini E., Bertinaria M. Giorgis M. | |
| Design and synthesis of encorafenib-based BRAF-V600E degraders | 2022 | Federica Blua, Marco Marino, Simone Gastaldi, Federica Maione, Eleonora Gianquinto, Federica Di Nicolantonio, Massimo Bertinaria | |
| Design and synthesis of INF195, a new NLRP3 Inflammasome Inhibitor with ex vivo cardioprotective effect | 2024 | Francesca Boccato, Simone Gastaldi, Magalì Giordano, Elisabetta Marini, Francesca Spyrakis, Pasquale Pagliaro, Claudia Penna, Massimo Bertinaria | |
| EVALUATION OF THE ANTIPYROPTOTIC ACTIVITY OF NEW INFLAMMASOME INHIBITORS | 2021 | Boscaro Valentina, Gastaldi Simone, Bertinaria Massimo, Gallicchio Margherita | |
| In silico study of NLRP3: towards selective inhibition with small molecules | 2019 | Alejandro Gómez García, Simone Gastaldi, Giulia Fumero, Massimo Bertinaria, José Luis Medina Franco | |
| In the search for new NLRP3 inhibitors: chemical modulation of the 1-(piperidin-4-yl)-1,3-dihydro-2 Hbenzo[d]imidazole-2-one scaffold | 2021 | Simone Gastaldi, Valentina Boscaro, Eleonora Gianquinto, Christina F. Sandall, Marta Giorgis, Elisabetta Marini, Federica Blua, Margherita Gallicchio, Francesca Spyrakis, Justin A. MacDonald, Massimo Bertinaria | |
| Inhibition of NLRP3 ATPase activity: a new strategy to fight chronic inflammatory diseases | 2019 | Simone Gastaldi, Federica Blua, Marta Giorgis, Elisabetta Marini, Massimo Bertinaria | |
| NEW NON-COVALENT INHIBITORS OF NLRP3 INFLAMMASOME ATPASE ACTIVITY | 2019 | Gastaldi, S; Marino, M.; Giorgis, M.; Marini, E.; Boscaro, V.; Gallicchio, M.; Bertinaria, M. | |
| Pharmacological characterization of new NLRP3 inflammasome inhibitors. | 2019 | Valentina Boscaro, Simone Gastaldi, Marco Marino, Marta Giorgis, Elisabetta Marini, Massimo Bertinaria, Margherita Gallicchio | |
| Targeting NLRP3 inflammasome: development of new covalent and non-covalent inhibitors of ATPase activity | 2019 | Elisabetta Marini, Simone Gastaldi, Marta Giorgis, Marco Marino, Valentina Boscaro, Margherita Gallicchio, Massimo Bertinaria |